Results 11 to 20 of about 34,736 (238)
SARS-CoV-2 pseudoparticles preferentially infect ectoderm in human embryonic tissues [PDF]
IntroductionThe early stages of human embryonic development are challenging to study in pregnant women.MethodsA “disease-in-a-dish” model was utilized to investigate SARS-CoV-2 infection of human embryonic stem cells and the three germ layers (ectoderm ...
Ann Song, Ann Song, Prue Talbot
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Hypohidrotic Ectodermal Dysplasia [PDF]
Ectodermal dysplasias are a heterogeneous group of disorders characterized by developmental dystrophies of ectodermal structures. These tissues include the skin, hair, nails, eccrine glands and teeth.1 Hypohydrotic Ectodermal Dysplasia is the most common type and is usually inherited as an X-linked recessive trait.
Gaurav Pratap, Singh, Vivek, Saxena
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DNA methylation of regulatory and growth-related genes contributes to fetal programming which is important for maintaining the correct development of three germ layers of the embryo that develope into different tissues and organs, and which persists into
Emanuele Capra +11 more
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Vertebrate dentitions arise at various places within the oropharyngeal cavity including the jaws, the palate, or the pharynx. These dentitions develop in a highly organized way, where new tooth germs are progressively added adjacent to the initiator ...
Vladimír Soukup +8 more
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Hypohidrotic Ectodermal Dysplasia
Ectodermal dysplasias (ED) are a group of inherited disorders characterized by dysplasia of structures of ectodermal origin, clinically classified into hypohidrotic and hidrotic forms. A 21-year-old female presented with history of hypohidrosis, thinning of scalp and eyebrow hair, xerotic skin, and periorbital and perioral wrinkling.
Bansal, Manish +2 more
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Differentiation of Human Induced Pluripotent Stem Cells to Mammary-like Organoids
Human induced pluripotent stem cells (iPSCs) can give rise to multiple cell types and hold great promise in regenerative medicine and disease-modeling applications.
Ying Qu +8 more
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Summary: The mechanism by which morphogenetic signals engage the regulatory networks responsible for early embryonic tissue patterning is incompletely understood.
Himanshu Kaul +8 more
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Suppressing Nodal Signaling Activity Predisposes Ectodermal Differentiation of Epiblast Stem Cells
Summary: The molecular mechanism underpinning the specification of the ectoderm, a transient germ-layer tissue, during mouse gastrulation was examined here in a stem cell-based model.
Chang Liu +12 more
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Par3 interacts with Prickle3 to generate apical PCP complexes in the vertebrate neural plate
Vertebrate neural tube formation depends on the coordinated orientation of cells in the tissue known as planar cell polarity (PCP). In the Xenopus neural plate, PCP is marked by the enrichment of the conserved proteins Prickle3 and Vangl2 at anterior ...
Ilya Chuykin +2 more
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Background: Ectodermal dysplasia is a rare hereditary disease, characterized by defects in the development of two to five tissues derived from the embryonic ectoderm. As a part of the manifestation, oligodontia can occur.
Sonja Zarkovic Gjurin +3 more
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