Results 11 to 20 of about 40,656 (278)

Ectoderm to mesoderm transition by down-regulation of actomyosin contractility

open access: yesPLoS Biology, 2021
Collective migration of cohesive tissues is a fundamental process in morphogenesis and is particularly well illustrated during gastrulation by the rapid and massive internalization of the mesoderm, which contrasts with the much more modest movements of ...
Leily Kashkooli   +2 more
exaly   +3 more sources

Transcriptional Profiling of Ectoderm Specification to Keratinocyte Fate in Human Embryonic Stem Cells [PDF]

open access: yesPLoS ONE, 2015
In recent years, several studies have shed light into the processes that regulate epidermal specification and homeostasis. We previously showed that a broad-spectrum γ-secretase inhibitor DAPT promoted early keratinocyte specification in human embryonic ...
Lin Hou, Lisa Chung, Hongyu Zhao
exaly   +3 more sources

BMP-dependent patterning of ectoderm tissue material properties modulates lateral mesendoderm cell migration during early zebrafish gastrulation

open access: yesCell Reports
Summary: Cell migration is a fundamental process during embryonic development. Most studies in vivo have focused on the migration of cells using the extracellular matrix (ECM) as their substrate for migration.
Stefania Tavano   +2 more
exaly   +5 more sources

A gene regulatory network underlying the formation of pre-placodal ectoderm in Xenopus laevis

open access: yesBMC Biology, 2018
Background The neural plate border ectoderm gives rise to key developmental structures during embryogenesis, including the neural crest and the preplacodal ectoderm.
Santosh Kumar Maharana   +1 more
doaj   +3 more sources

SARS-CoV-2 pseudoparticles preferentially infect ectoderm in human embryonic tissues [PDF]

open access: yesFrontiers in Cell and Developmental Biology
IntroductionThe early stages of human embryonic development are challenging to study in pregnant women.MethodsA “disease-in-a-dish” model was utilized to investigate SARS-CoV-2 infection of human embryonic stem cells and the three germ layers (ectoderm ...
Ann Song, Ann Song, Prue Talbot
doaj   +2 more sources

Requirement of Smad4 from Ocular Surface Ectoderm for Retinal Development. [PDF]

open access: yesPLoS ONE, 2016
Microphthalmia is characterized by abnormally small eyes and usually retinal dysplasia, accounting for up to 11% of the blindness in children. Right now there is no effective treatment for the disease, and the underlying mechanisms, especially how ...
Jing Li   +10 more
doaj   +2 more sources

BMP4 and FGF strongly induce differentiation of mouse ES cells into oral ectoderm

open access: yesStem Cell Research, 2015
During embryonic development, oral ectoderm differentiates into the adenohypophysis, dental epithelia, salivary glands, and nasal pit. Few reports exist concerning the induction of oral ectoderm from embryonic stem (ES) cells.
Hiroshi Ochiai   +12 more
doaj   +2 more sources

Distinct requirements for cranial ectoderm and mesenchyme-derived wnts in specification and differentiation of osteoblast and dermal progenitors.

open access: yesPLoS Genetics, 2014
The cranial bones and dermis differentiate from mesenchyme beneath the surface ectoderm. Fate selection in cranial mesenchyme requires the canonical Wnt effector molecule β-catenin, but the relative contribution of Wnt ligand sources in this process ...
L Henry Goodnough   +5 more
doaj   +2 more sources

Derivation and characteristics of induced pluripotent stem cells from a patient with acute myelitis

open access: yesFrontiers in Cell and Developmental Biology, 2023
The emergence and development of induced pluripotent stem cells (iPSCs) provides an approach to understand the regulatory mechanisms of cell pluripotency and demonstrates the great potential of iPSCs in disease modeling. Acute myelitis defines a group of
Shuo Cao   +25 more
doaj   +1 more source

Ectodermal dysplasias

open access: yesPortuguese Journal of Dermatology and Venereology, 2022
Ectodermal dysplasias are a heterogeneous group of rare inherited disorders. Molecular findings and clarification of cell signaling processes and ectodermal-mesenchyme interaction enabled the development of a clinical-functional model, which in turn helps to explain clinical signs, with variability in severity, associated non-ectodermal abnormalities ...
João, AL   +3 more
openaire   +3 more sources

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