Results 31 to 40 of about 35,082 (162)

BMP4 and FGF strongly induce differentiation of mouse ES cells into oral ectoderm

Stem Cell Research, 2015
During embryonic development, oral ectoderm differentiates into the adenohypophysis, dental epithelia, salivary glands, and nasal pit. Few reports exist concerning the induction of oral ectoderm from embryonic stem (ES) cells.
Hiroshi Ochiai, Hidetaka Suga, Tomiko Yamada, Mayu Sakakibara, Takatoshi Kasai, Chikafumi Ozone, Koichiro Ogawa, Motomitsu Goto, Ryoichi Banno, Shin Tsunekawa, Yoshihisa Sugimura, Hiroshi Arima, Yutaka Oiso   +12 more
doaj   +1 more source

Requirement of Smad4 from Ocular Surface Ectoderm for Retinal Development. [PDF]

PLoS ONE, 2016
Microphthalmia is characterized by abnormally small eyes and usually retinal dysplasia, accounting for up to 11% of the blindness in children. Right now there is no effective treatment for the disease, and the underlying mechanisms, especially how ...
Jing Li, Shusheng Wang, Chastain Anderson, Fangkun Zhao, Yu Qin, Di Wu, Xinwei Wu, Jia Liu, Xuefei He, Jiangyue Zhao, Jinsong Zhang   +10 more
doaj   +1 more source

Hypohidrotic Ectodermal Dysplasia

International Journal of Trichology, 2012
Ectodermal dysplasias (ED) are a group of inherited disorders characterized by dysplasia of structures of ectodermal origin, clinically classified into hypohidrotic and hidrotic forms. A 21-year-old female presented with history of hypohidrosis, thinning of scalp and eyebrow hair, xerotic skin, and periorbital and perioral wrinkling.
Bansal, Manish, Manchanda, Kajal, Pandey, Shyam Sunder   +2 more
openaire   +6 more sources

Sp6 and Sp8 transcription factors control AER formation and dorsal-ventral patterning in limb development. [PDF]

PLoS Genetics, 2014
The formation and maintenance of the apical ectodermal ridge (AER) is critical for the outgrowth and patterning of the vertebrate limb. The induction of the AER is a complex process that relies on integrated interactions among the Fgf, Wnt, and Bmp ...
Endika Haro, Irene Delgado, Marisa Junco, Yoshihiko Yamada, Ahmed Mansouri, Kerby C Oberg, Marian A Ros   +6 more
doaj   +1 more source

Multidisciplinary interventions in ectodermal dysplasia: A clinical case report

Journal of Family Medicine and Primary Care
Ectodermal dysplasia (ED) is a spectrum of inherited disorders that compromise the development and function of ectodermal structures, like hair, nails, and teeth.
Andres Chaponan-Lavalle, Luis Guillermo Azanedo Garcia, Karla Hernandez Randich, Yolanda Chaponan-Lavalle, Karina Ordaya-Gonzales, Jose Arriola-Montenegro   +5 more
doaj   +1 more source

In vitro Characteristics of Heterogeneous Equine Hoof Progenitor Cell Isolates

Frontiers in Bioengineering and Biotechnology, 2019
Damage to an ectodermal-mesodermal interface like that in the equine hoof and human finger nail bed can permanently alter tissue structure and associated function.
Qingqiu Yang, Vanessa Marigo Rocha Pinto, Wei Duan, Erica E. Paxton, Jenna H. Dessauer, William Ryan, Mandi J. Lopez   +6 more
doaj   +1 more source

Teratogenic Rubella Virus Alters the Endodermal Differentiation Capacity of Human Induced Pluripotent Stem Cells

Cells, 2019
The study of congenital virus infections in humans requires suitable ex vivo platforms for the species-specific events during embryonal development. A prominent example for these infections is rubella virus (RV) which most commonly leads to defects in ...
Nicole C. Bilz, Edith Willscher, Hans Binder, Janik Böhnke, Megan L. Stanifer, Denise Hübner, Steeve Boulant, Uwe G. Liebert, Claudia Claus   +8 more
doaj   +1 more source

Root resorption: Focus on signs and symptoms of importance for avoiding root resorption during orthodontic treatment

Dental Hypotheses, 2014
Introduction: This paper summarizes the different conditions, which have a well-known influence on the resorption of tooth roots, exemplified by trauma and orthodontic treatment.
Inger Kjaer
doaj   +1 more source

Top-Down Inhibition of BMP Signaling Enables Robust Induction of hPSCs Into Neural Crest in Fully Defined, Xeno-free Conditions

Stem Cell Reports, 2017
Defects in neural crest development have been implicated in many human disorders, but information about human neural crest formation mostly depends on extrapolation from model organisms.
James O.S. Hackland, Tom J.R. Frith, Oliver Thompson, Ana Marin Navarro, Martin I. Garcia-Castro, Christian Unger, Peter W. Andrews   +6 more
doaj   +1 more source

Antero-posterior ectoderm patterning by canonical Wnt signaling during ascidian development. [PDF]

PLoS Genetics, 2019
Wnt/β-catenin signaling is an ancient pathway in metazoans and controls various developmental processes, in particular the establishment and patterning of the embryonic primary axis. In vertebrates, a graded Wnt activity from posterior to anterior endows
Stacy Feinberg, Agnès Roure, Julie Piron, Sébastien Darras   +3 more
doaj   +1 more source