Results 31 to 40 of about 40,656 (278)

Cues from neuroepithelium and surface ectoderm maintain neural crest-free regions within cranial mesenchyme of the developing chick [PDF]

open access: yes, 2002
Within the developing vertebrate head, neural crest cells (NCCs) migrate from the dorsal surface of the hindbrain into the mesenchyme adjacent to rhombomeres (r)1 plus r2, r4 and r6 in three segregated streams.
Golding, Jon P.   +2 more
core   +1 more source

Differentiation of Human Induced Pluripotent Stem Cells to Mammary-like Organoids

open access: yesStem Cell Reports, 2017
Human induced pluripotent stem cells (iPSCs) can give rise to multiple cell types and hold great promise in regenerative medicine and disease-modeling applications.
Ying Qu   +8 more
doaj   +1 more source

Virtual cells in a virtual microenvironment recapitulate early development-like patterns in human pluripotent stem cell colonies

open access: yesStem Cell Reports, 2023
Summary: The mechanism by which morphogenetic signals engage the regulatory networks responsible for early embryonic tissue patterning is incompletely understood.
Himanshu Kaul   +8 more
doaj   +1 more source

Suppressing Nodal Signaling Activity Predisposes Ectodermal Differentiation of Epiblast Stem Cells

open access: yesStem Cell Reports, 2018
Summary: The molecular mechanism underpinning the specification of the ectoderm, a transient germ-layer tissue, during mouse gastrulation was examined here in a stem cell-based model.
Chang Liu   +12 more
doaj   +1 more source

Par3 interacts with Prickle3 to generate apical PCP complexes in the vertebrate neural plate

open access: yeseLife, 2018
Vertebrate neural tube formation depends on the coordinated orientation of cells in the tissue known as planar cell polarity (PCP). In the Xenopus neural plate, PCP is marked by the enrichment of the conserved proteins Prickle3 and Vangl2 at anterior ...
Ilya Chuykin   +2 more
doaj   +1 more source

Early prosthetic rehabilitation of severe oligodontia with implant–retained overdenture: A case report

open access: yesZdravniški Vestnik, 2020
Background: Ectodermal dysplasia is a rare hereditary disease, characterized by defects in the development of two to five tissues derived from the embryonic ectoderm. As a part of the manifestation, oligodontia can occur.
Sonja Zarkovic Gjurin   +3 more
doaj   +1 more source

Evaluation of Ectodermal Dysplasia

open access: yesThe Kaohsiung Journal of Medical Sciences, 2006
This case series report outlines possible cranio‐maxillofacial deformation consequences associated with ectodermal dysplasia (ED) and embryonic malformations, including dental agenesis. Also described are the oral aspects and rehabilitation. A total of 14 ED patients (7 males and 7 females, aged 5‐45 years) underwent clinical examination before ...
Başkan, Zelal   +7 more
openaire   +3 more sources

Phenotypic and Genotypic Features of Thai Patients With Nonsyndromic Tooth Agenesis and WNT10A Variants

open access: yesFrontiers in Physiology, 2020
Tooth agenesis is one of the most common orodental anomalies that demonstrate phenotypic and genotypic heterogeneity with a prevalence of 2.5%–7%. Mutations in WNT10A have been proposed to be the most common cause of nonsyndromic tooth agenesis (NSTA ...
Charinya Kanchanasevee   +8 more
doaj   +1 more source

Role of Smad4 from ocular surface ectoderm in retinal vasculature development [PDF]

open access: yesInternational Journal of Ophthalmology, 2020
"AIM: To investigate how signals from lens regulate retinal vascular development and neovascularization. METHODS: Le-Cre transgenic mouse line was employed to inactivate Smad4 in the surface ectoderm selectively.
Jing Li   +3 more
doaj   +1 more source

Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm. [PDF]

open access: yesPLoS Genetics, 2010
Echinoderms, which are phylogenetically related to vertebrates and produce large numbers of transparent embryos that can be experimentally manipulated, offer many advantages for the analysis of the gene regulatory networks (GRN) regulating germ layer ...
Alexandra Saudemont   +12 more
doaj   +1 more source

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