Results 31 to 40 of about 40,656 (278)
Cues from neuroepithelium and surface ectoderm maintain neural crest-free regions within cranial mesenchyme of the developing chick [PDF]
Within the developing vertebrate head, neural crest cells (NCCs) migrate from the dorsal surface of the hindbrain into the mesenchyme adjacent to rhombomeres (r)1 plus r2, r4 and r6 in three segregated streams.
Golding, Jon P. +2 more
core +1 more source
Differentiation of Human Induced Pluripotent Stem Cells to Mammary-like Organoids
Human induced pluripotent stem cells (iPSCs) can give rise to multiple cell types and hold great promise in regenerative medicine and disease-modeling applications.
Ying Qu +8 more
doaj +1 more source
Summary: The mechanism by which morphogenetic signals engage the regulatory networks responsible for early embryonic tissue patterning is incompletely understood.
Himanshu Kaul +8 more
doaj +1 more source
Suppressing Nodal Signaling Activity Predisposes Ectodermal Differentiation of Epiblast Stem Cells
Summary: The molecular mechanism underpinning the specification of the ectoderm, a transient germ-layer tissue, during mouse gastrulation was examined here in a stem cell-based model.
Chang Liu +12 more
doaj +1 more source
Par3 interacts with Prickle3 to generate apical PCP complexes in the vertebrate neural plate
Vertebrate neural tube formation depends on the coordinated orientation of cells in the tissue known as planar cell polarity (PCP). In the Xenopus neural plate, PCP is marked by the enrichment of the conserved proteins Prickle3 and Vangl2 at anterior ...
Ilya Chuykin +2 more
doaj +1 more source
Background: Ectodermal dysplasia is a rare hereditary disease, characterized by defects in the development of two to five tissues derived from the embryonic ectoderm. As a part of the manifestation, oligodontia can occur.
Sonja Zarkovic Gjurin +3 more
doaj +1 more source
Evaluation of Ectodermal Dysplasia
This case series report outlines possible cranio‐maxillofacial deformation consequences associated with ectodermal dysplasia (ED) and embryonic malformations, including dental agenesis. Also described are the oral aspects and rehabilitation. A total of 14 ED patients (7 males and 7 females, aged 5‐45 years) underwent clinical examination before ...
Başkan, Zelal +7 more
openaire +3 more sources
Tooth agenesis is one of the most common orodental anomalies that demonstrate phenotypic and genotypic heterogeneity with a prevalence of 2.5%–7%. Mutations in WNT10A have been proposed to be the most common cause of nonsyndromic tooth agenesis (NSTA ...
Charinya Kanchanasevee +8 more
doaj +1 more source
Role of Smad4 from ocular surface ectoderm in retinal vasculature development [PDF]
"AIM: To investigate how signals from lens regulate retinal vascular development and neovascularization. METHODS: Le-Cre transgenic mouse line was employed to inactivate Smad4 in the surface ectoderm selectively.
Jing Li +3 more
doaj +1 more source
Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm. [PDF]
Echinoderms, which are phylogenetically related to vertebrates and produce large numbers of transparent embryos that can be experimentally manipulated, offer many advantages for the analysis of the gene regulatory networks (GRN) regulating germ layer ...
Alexandra Saudemont +12 more
doaj +1 more source

