Results 1 to 10 of about 741,453 (284)
The p53 gene expression and its developmental regulation in schistosomes [PDF]
We have studied the gene expression, especially of the oncoproteins, and its regulation in schistosomes. Schistosomes have a complex life cycle with defined dimorphic lifestyle. The parasite are so far unique in biology in expressing oncogene products in
Manami Tanaka +2 more
doaj +4 more sources
Developmental regulation of GABAergic gene expression in forebrain cholinergic neurons
Acetylcholine and GABA are often co-released, including from VIP-expressing neurons of the cortex, cortically-projecting neurons of the globus pallidus externus and basal forebrain, and hippocampal-projecting neurons of the medial septum.
Adam J. Granger +4 more
doaj +3 more sources
Thermal and developmental regulation of gene expression in Trypanosoma cruzi [PDF]
C. M. A. Soares +6 more
doaj +4 more sources
Maternal diabetes and obesity in pregnancy are well-known risk factors for structural birth defects, including neural tube defects and congenital heart defects.
Man Zhang +4 more
doaj +1 more source
Maternal diabetes in early pregnancy increases the risk for birth defects in the offspring, particularly heart, and neural tube defects. While elevated glucose levels are characteristic for diabetic pregnancies, these are also accompanied by ...
Claudia Kappen +3 more
doaj +1 more source
Broad spectrum of CRISPR-induced edits in an embryonic lethal gene
Mendelian genetics poses practical limitations on the number of mutant genes that can be investigated simultaneously for their roles in embryonic development in the mouse.
Kayla T. B. Fuselier +2 more
doaj +1 more source
Summary: The ARID1A subunit of SWI/SNF chromatin remodeling complexes is a potent tumor suppressor. Here, a degron is applied to detect rapid loss of chromatin accessibility at thousands of loci where ARID1A acts to generate accessible minidomains of ...
Seraina BlĂĽmli +13 more
doaj +1 more source
Differential responses to maternal diabetes in embryo and visceral yolk sac
Introduction: Maternal diabetes during pregnancy is well known to be associated with a higher risk for structural birth defects in the offspring. Recent searches for underlying mechanisms have largely focused on aberrant processes in the embryo itself ...
J. Michael Salbaum +3 more
doaj +1 more source
Developmental Regulation of Angiotensinogen Gene Expression in Sheep [PDF]
It has been suggested that the liver is not the main source of angiotensinogen during fetal life in rats, but that the kidney is an important site of fetal angiotensinogen synthesis. In an effort to determine if this phenomenon is specific to the rat or applicable to other species, we compared the ontogenic changes in hepatic and renal angiotensinogen ...
Olson, Ann Louise +2 more
openaire +2 more sources
Global Gene Expression Profiling of Individual Human Oocytes and Embryos Demonstrates Heterogeneity in Early Development [PDF]
Early development in humans is characterised by low and variable embryonic viability, reflected in low fecundity and high rates of miscarriage, relative to other mammals.
Brison, Daniel R. +4 more
core +5 more sources

