Results 11 to 20 of about 741,473 (304)
Development is a complex process involving precise regulation. Developmental regulation may vary in tissues and individuals, and is often altered in disorders.
Yuqiu Zhou, Li Tao, Ying Zhu
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chHDAC11 mRNA Expression During Prenatal and Postnatal Chicken (Gallus gallus) Brain Development
Background: Histone deacetylation plays an essential role in transcriptional regulation of cell cycle progression and other evolutionary processes. Several results confirm the importance of the latest found HDAC11 gene to deacetylate histone core in ...
Farzam Ajamian +4 more
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BUB-1 targets PP2A:B56 to regulate chromosome congression during meiosis I in C. elegans oocytes
Protein Phosphatase 2A (PP2A) is a heterotrimer composed of scaffolding (A), catalytic (C), and regulatory (B) subunits. PP2A complexes with B56 subunits are targeted by Shugoshin and BUBR1 to protect centromeric cohesion and stabilise kinetochore ...
Laura Bel Borja +9 more
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Mutations in the ARID1B subunit of the BAF chromatin remodeling complex are associated with the neurodevelopmental Coffin-Siris syndrome. Here the authors reveal that there is a transition from ARID1A-containing complexes to ARID1B during cranial neural ...
Luca Pagliaroli +14 more
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The regulation of Hox gene expression during animal development [PDF]
Hox genes encode a family of transcriptional regulators that elicit distinct developmental programmes along the head-to-tail axis of animals. The specific regional functions of individual Hox genes largely reflect their restricted expression patterns ...
Alonso, Claudio R, Mallo, Moisés
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Genetic variation in voltage-gated sodium (NaV) channels is a significant contributor to neurodevelopmental disorders. NaV channel alpha subunits are encoded by the SCNxA family and four are predominately expressed in the brain: SCN1A, SCN2A, SCN3A, and ...
Jacqueline Heighway +8 more
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Developmental regulation and expression of the zebrafish connexin43 gene [PDF]
AbstractWe cloned and sequenced the zebrafish (Danio rerio) connexin43 (Cx43α1) gene. The predicted protein sequence shows a high degree of sequence conservation. Transcript analyses revealed multiple transcription start sites and a potential alternative transcript encoding a N‐terminally truncated Cx43α1 protein.
Bishwanath, Chatterjee +12 more
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Since its discovery more than 25 years ago, great progress has been made in our understanding of the unfolded protein response (UPR), a homeostatic mechanism that adjusts endoplasmic reticulum (ER) function to satisfy the physiological demands of the ...
G. Elif Karagöz +2 more
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Phylogeny, expression patterns and regulation of DNA Methyltransferases in early development of the flatfish, Solea senegalensis [PDF]
Background: The identification of DNA methyltransferases (Dnmt) expression patterns during development and their regulation is important to understand the epigenetic mechanisms that modulate larval plasticity in marine fish.
Armesto, Paula +5 more
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Transcription of satellite DNAs in insects [PDF]
Chromatin condensation is an important regulatory mechanism of gene silencing as well as gene activation for the hundreds of functional protein genes harbored in heterochromatic regions of different insect species.
D. Ugarkovic +3 more
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