Results 11 to 20 of about 7,339,069 (294)

Epigenetic regulation during fetal femur development: DNA methylation matters. [PDF]

open access: yesPLoS ONE, 2013
Epigenetic modifications are heritable changes in gene expression without changes in DNA sequence. DNA methylation has been implicated in the control of several cellular processes including differentiation, gene regulation, development, genomic ...
María C de Andrés   +6 more
doaj   +2 more sources

Stochastic neural network models for gene regulatory networks [PDF]

open access: yes, 2003
Recent advances in gene-expression profiling technologies provide large amounts of gene expression data. This raises the possibility for a functional understanding of genome dynamics by means of mathematical modelling.
Tian, T., Burrage, K.
core   +9 more sources

RNA interference is ineffective as a routine method for gene silencing in chick embryos as monitored by fgf8 silencing. [PDF]

open access: yes, 2013
The in vivo accessibility of the chick embryo makes it a favoured model system for experimental developmental biology. Although the range of available techniques now extends to miss-expression of genes through in ovo electroporation, it remains difficult
Bueno i Torrens, David, 1965-   +1 more
core   +6 more sources

Differential responses to maternal diabetes in embryo and visceral yolk sac

open access: yesFrontiers in Cell and Developmental Biology, 2023
Introduction: Maternal diabetes during pregnancy is well known to be associated with a higher risk for structural birth defects in the offspring. Recent searches for underlying mechanisms have largely focused on aberrant processes in the embryo itself ...
J. Michael Salbaum   +3 more
doaj   +1 more source

TempShift Reveals the Sequential Development of Human Neocortex and Skewed Developmental Timing of Down Syndrome Brains

open access: yesBrain Sciences, 2023
Development is a complex process involving precise regulation. Developmental regulation may vary in tissues and individuals, and is often altered in disorders.
Yuqiu Zhou, Li Tao, Ying Zhu
doaj   +1 more source

chHDAC11 mRNA Expression During Prenatal and Postnatal Chicken (Gallus gallus) Brain Development

open access: yesCaspian Journal of Neurological Sciences, 2022
Background: Histone deacetylation plays an essential role in transcriptional regulation of cell cycle progression and other evolutionary processes. Several results confirm the importance of the latest found HDAC11 gene to deacetylate histone core in ...
Farzam Ajamian   +4 more
doaj   +1 more source

BUB-1 targets PP2A:B56 to regulate chromosome congression during meiosis I in C. elegans oocytes

open access: yeseLife, 2020
Protein Phosphatase 2A (PP2A) is a heterotrimer composed of scaffolding (A), catalytic (C), and regulatory (B) subunits. PP2A complexes with B56 subunits are targeted by Shugoshin and BUBR1 to protect centromeric cohesion and stabilise kinetochore ...
Laura Bel Borja   +9 more
doaj   +1 more source

Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in ARID1B-related neurodevelopmental disorders

open access: yesNature Communications, 2021
Mutations in the ARID1B subunit of the BAF chromatin remodeling complex are associated with the neurodevelopmental Coffin-Siris syndrome. Here the authors reveal that there is a transition from ARID1A-containing complexes to ARID1B during cranial neural ...
Luca Pagliaroli   +14 more
doaj   +1 more source

A chicken homeo box gene with developmentally regulated expression [PDF]

open access: yesFEBS Letters, 1989
Several homeo box sequences were isolated from a chicken (Gallus domesticus) genomic library. One phage, λGG7, was chosen for further study and the single homeo box sequence it contains was characterized. The sequence of the homeo box revealed it to be a distant member of the Antp class of homeo boxes.
Fainsod, Abraham, Gruenbaum, Yosef
openaire   +2 more sources

Role of Topoisomerase IIβ in the Expression of Developmentally Regulated Genes [PDF]

open access: yesMolecular and Cellular Biology, 2006
Mice lacking topoisomerase IIbeta (TopIIbeta) are known to exhibit a perinatal death phenotype. In the current study, transcription profiles of the brains of wild-type and top2beta knockout mouse embryos were generated. Surprisingly, only a small number (1 to 4%) of genes were affected in top2beta knockout embryos. However, the expression of nearly 30%
Yi Lisa, Lyu   +5 more
openaire   +2 more sources

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