A chicken homeo box gene with developmentally regulated expression [PDF]
FEBS Letters, 1989 Several homeo box sequences were isolated from a chicken (Gallus domesticus) genomic library. One phage, λGG7, was chosen for further study and the single homeo box sequence it contains was characterized. The sequence of the homeo box revealed it to be a distant member of the Antp class of homeo boxes.
Fainsod, Abraham, Gruenbaum, Yosef
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Developmental regulation of proenkephalin gene expression in osteoblasts. [PDF]
Molecular Endocrinology, 1995 Proenkephalin (PENK), a classically defined opioid gene, was originally thought to be expressed almost exclusively in the mature nervous and neuroendocrine systems. In the last few years, it was demonstrated, however, that high levels of PENK messenger RNA and PENK-derived peptides are expressed in embryonic mesenchymal tissues during differentiation ...
H, Rosen +4 more
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Dynamic association of NUP98 with the human genome. [PDF]
PLoS Genetics, 2013 Faithful execution of developmental gene expression programs occurs at multiple levels and involves many different components such as transcription factors, histone-modification enzymes, and mRNA processing proteins.
Yun Liang +4 more
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Nascent RNA sequencing reveals mechanisms of gene regulation in the human malaria parasite Plasmodium falciparum. [PDF]
, 2017 Gene expression in Plasmodium falciparum is tightly regulated to ensure successful propagation of the parasite throughout its complex life cycle. The earliest transcriptomics studies in P.
Batugedara, Gayani +5 more
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Mapping Native R-Loops Genome-wide Using a Targeted Nuclease Approach
Cell Reports, 2019 Summary: R-loops are three-stranded DNA:RNA hybrids that are implicated in many nuclear processes. While R-loops may have physiological roles, the formation of stable, aberrant R-loops has been observed in neurological disorders and cancers.
Qingqing Yan +3 more
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Conservation of peripheral nervous system formation mechanisms in divergent ascidian embryos
eLife, 2020 Ascidians with very similar embryos but highly divergent genomes are thought to have undergone extensive developmental system drift. We compared, in four species (Ciona and Phallusia for Phlebobranchia, Molgula and Halocynthia for Stolidobranchia), gene ...
Joshua F Coulcher +8 more
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A connection between stress and development in the multicelular prokaryote Streptomyces coelicolor [PDF]
, 2001 Morphological changes leading to aerial mycelium formation and sporulation in the mycelial bacterium Streptomyces coelicolor rely on establishing distinct patterns of gene expression in separate regions of the colony.
Bucca G. +24 more
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HnRNP-like proteins as post-transcriptional regulators [PDF]
, 2014 Plant cells contain a diverse repertoire of RNA-binding proteins (RBPs) that coordinate a network of post-transcriptional regulation. RBPs govern diverse developmental processes by modulating the gene expression of specific transcripts.
Ho, Chai Ling +2 more
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Poly(ADP-ribosyl)ating enzymes cooperate to coordinate development
Scientific Reports, 2022 The transcriptome is subject to rapid and massive changes during the transition between developmental stages. These changes require tight control to avoid the undesired reactivation of gene expression that is only important for previous developmental ...
Guillaume Bordet +2 more
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Stochastic neural network models for gene regulatory networks [PDF]
, 2003 Recent advances in gene-expression profiling technologies provide large amounts of gene expression data. This raises the possibility for a functional understanding of genome dynamics by means of mathematical modelling.
Burrage, K., Tian, T.
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