Splayed : a chromatin remodeler regulating tissue specific gene silencing and developmental timing [PDF]
A number of mechanisms that contribute to epigenetic regulation of gene expression have been described in plants. The concert actions of these mechanisms contribute to proper patterning of gene expression within organs and tissues, therefore insuring ...
Fal, Kateryna
core +1 more source
Since its discovery more than 25 years ago, great progress has been made in our understanding of the unfolded protein response (UPR), a homeostatic mechanism that adjusts endoplasmic reticulum (ER) function to satisfy the physiological demands of the ...
G. Elif Karagöz +2 more
doaj +1 more source
A compartmentalized regulator of developmental gene expression in Bacillus subtilis [PDF]
We have identified a new Bacillus subtilis gene, spoVT, whose gene product is homologous to the transcriptional regulator AbrB and serves as a regulator of E sigmaG-controlled gene expression. SpoVT acts both positively and negatively in controlling sigmaG-dependent gene expression, providing an additional level of refinement to forespore gene ...
I, Bagyan, J, Hobot, S, Cutting
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Stochastic neural network models for gene regulatory networks [PDF]
Recent advances in gene-expression profiling technologies provide large amounts of gene expression data. This raises the possibility for a functional understanding of genome dynamics by means of mathematical modelling.
Burrage K. +3 more
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Regulation of Trypanosoma brucei Total and Polysomal mRNA during Development within Its Mammalian Host [PDF]
The gene expression of Trypanosoma brucei has been examined extensively in the blood of mammalian hosts and in forms found in the midgut of its arthropod vector, the tsetse fly.
Ivens, A +40 more
core +1 more source
Mapping Native R-Loops Genome-wide Using a Targeted Nuclease Approach
Summary: R-loops are three-stranded DNA:RNA hybrids that are implicated in many nuclear processes. While R-loops may have physiological roles, the formation of stable, aberrant R-loops has been observed in neurological disorders and cancers.
Qingqing Yan +3 more
doaj +1 more source
Conservation of peripheral nervous system formation mechanisms in divergent ascidian embryos
Ascidians with very similar embryos but highly divergent genomes are thought to have undergone extensive developmental system drift. We compared, in four species (Ciona and Phallusia for Phlebobranchia, Molgula and Halocynthia for Stolidobranchia), gene ...
Joshua F Coulcher +8 more
doaj +1 more source
Dynamic association of NUP98 with the human genome. [PDF]
Faithful execution of developmental gene expression programs occurs at multiple levels and involves many different components such as transcription factors, histone-modification enzymes, and mRNA processing proteins.
Yun Liang +4 more
doaj +1 more source
Differential timing of gene expression regulation between leptocephali of the two Anguilla eel species in the Sargasso Sea [PDF]
The unique life-history characteristics of North Atlantic catadromous eels have long intrigued evolutionary biologists, especially with respect to mechanisms that could explain their persistence as two ecologically very similar but reproductively and ...
Maes, Gregory E. +24 more
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Developmental regulation of proenkephalin gene expression in osteoblasts. [PDF]
Proenkephalin (PENK), a classically defined opioid gene, was originally thought to be expressed almost exclusively in the mature nervous and neuroendocrine systems. In the last few years, it was demonstrated, however, that high levels of PENK messenger RNA and PENK-derived peptides are expressed in embryonic mesenchymal tissues during differentiation ...
H, Rosen +4 more
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