Results 31 to 40 of about 741,473 (304)

DNA methylation-free Arabidopsis reveals crucial roles of DNA methylation in regulating gene expression and development

Nature Communications, 2022
Our understanding of the extent of involvement of DNA methylation in genome-wide gene regulation and plant developmental control is incomplete. Here, the authors knock out all five known DNA methyltransferases and show the developmental and gene ...
Li He, Huan Huang, Mariem Bradai, Cheng Zhao, Yin You, Jun Ma, Lun Zhao, Rosa Lozano-Durán, Jian-Kang Zhu   +8 more
doaj   +1 more source

mRNA Cap Methylation in Pluripotency and Differentiation

Cell Reports, 2016
The mRNA cap recruits factors essential for transcript processing and translation initiation. We report that regulated mRNA cap methylation is a feature of embryonic stem cell (ESC) differentiation. Expression of the mRNA cap methyltransferase activating
Laura Grasso, Olga Suska, Lindsay Davidson, Thomas Gonatopoulos-Pournatzis, Ritchie Williamson, Lize Wasmus, Simone Wiedlich, Mark Peggie, Marios P. Stavridis, Victoria H. Cowling   +9 more
doaj   +1 more source

Transcriptome sequencing and developmental regulation of gene expression in Anopheles aquasalis. [PDF]

PLoS Neglected Tropical Diseases, 2014
BACKGROUND:Anopheles aquasalis is a major malaria vector in coastal areas of South and Central America where it breeds preferentially in brackish water.
André L Costa-da-Silva, Osvaldo Marinotti, José M C Ribeiro, Maria C P Silva, Adriana R Lopes, Michele S Barros, Anderson Sá-Nunes, Bianca B Kojin, Eneas Carvalho, Lincoln Suesdek, Mário Alberto C Silva-Neto, Anthony A James, Margareth L Capurro   +12 more
doaj   +1 more source

RNA interference in marine and freshwater sponges [PDF]

, 2011
Background: The marine sponge Tethya wilhelma and the freshwater sponge Ephydatia muelleri are emerging model organisms to study evolution, gene regulation, development, and physiology in non-bilaterian animal systems. Thus far, functional methods (i.e.,
Cieniewicz, Brandon, Danka, Elizabeth S., Haen, Karri M., Hammel, Jörg U., Hill, April L., Hill, Malcolm S., Knight, Scott W., Lavrov, Dennis V., Nickel, Michael, Posfai, Dora, Rivera, Ajna S., Winters, Ian P., Wörheide, Gert   +12 more
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csal1 Is Controlled by a Combination of FGF and Wnt Signals in Developing Limb Buds [PDF]

, 2002
While some of the signaling molecules that govern establishment of the limb axis have been characterized, little is known about the downstream effector genes that interpret these signals.
Akita, Andrea E Münsterberg, Capdevila, Chang, Chen, Crossley, de Celis, de Celis, Dealy, Dollé, Drossopoulou, Echelard, Elizabeth R Farrell, Hamburger, Henrique, Hirsinger, Hollemann, Izpisúa-Belmonte, Johnson, Jürgens, Kengaku, Kohlhase, Kohlhase, Koster, Krauss, Kühnlein, Kühnlein, Lamb, Laufer, Lecuit, Lopezmartinez, Martin, Münsterberg, Nellen, Niswander, Niswander, Ott, Parr, Riddle, Riddle, Schwabe, Smith, Sturtevant, Summerbell, Takahashi, Tickle, Tickle, Vogel, Wagner-Bernholz, Yang, Zou   +50 more
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Sphingosine Phosphate Lyase Expression Is Essential for Normal Development in Caenorhabditis elegans [PDF]

, 2003
Sphingolipids are ubiquitous membrane constituents whose metabolites function as signaling molecules in eukaryotic cells. Sphingosine 1-phosphate, a key sphingolipid second messenger, regulates proliferation, motility, invasiveness, and programmed cell ...
Fyrst, Henrik, Heinecke, Karie, Mendel, Jane, Saba, Julie D.   +3 more
core   +1 more source

Regulation of globin gene expression: boxes and borders [PDF]

, 2001
The experimental work presented in this thesis pertains to the regulation of gene expression and focuses on the regulation of the B globin genes. The expression of the globin genes is restricted to the erythropoietic tissue and is regulated during ...
Zafarana, G. (Gaetano)
core   +6 more sources

Optogenetic Control of Gene Expression in Drosophila. [PDF]

PLoS ONE, 2015
To study the molecular mechanism of complex biological systems, it is important to be able to artificially manipulate gene expression in desired target sites with high precision.
Yick-Bun Chan, Olga V Alekseyenko, Edward A Kravitz   +2 more
doaj   +1 more source

Spatiotemporal dynamics of the postnatal developing primate brain transcriptome. [PDF]

, 2015
Developmental changes in the temporal and spatial regulation of gene expression drive the emergence of normal mature brain function, while disruptions in these processes underlie many neurodevelopmental abnormalities.
Amaral, David G, Bakken, Trygve E, Bennett, Jeffrey L, Bernard, Amy, Bertagnolli, Darren, Geschwind, Daniel H, Lee, Chang-Kyu, Lein, Ed S, Luo, Rui, Miller, Jeremy A, Parikshak, Neelroop N, Smith, Kimberly A, Sunkin, Susan M   +12 more
core   +1 more source

Developmental regulation of trypanosome mitochondrial gene expression.

Journal of Biological Chemistry, 1987
Mitochondrial respiratory activities in the protozoan parasite Trypanosoma brucei are developmentally regulated. The trypanosomes in the mammalian bloodstream derive ATP entirely from glycolysis. The trypanosomes found in the midgut of the insect vector or in culture at 26 degrees C have fully functional mitochondria with cytochrome-mediated ...
E F, Michelotti, S L, Hajduk
openaire   +2 more sources