Results 31 to 40 of about 7,339,069 (294)

Conservation of peripheral nervous system formation mechanisms in divergent ascidian embryos

eLife, 2020
Ascidians with very similar embryos but highly divergent genomes are thought to have undergone extensive developmental system drift. We compared, in four species (Ciona and Phallusia for Phlebobranchia, Molgula and Halocynthia for Stolidobranchia), gene ...
Joshua F Coulcher, Agnès Roure, Rafath Chowdhury, Méryl Robert, Laury Lescat, Aurélie Bouin, Juliana Carvajal Cadavid, Hiroki Nishida, Sébastien Darras   +8 more
doaj   +1 more source

Developmental regulation of proenkephalin gene expression in osteoblasts. [PDF]

Molecular Endocrinology, 1995
Proenkephalin (PENK), a classically defined opioid gene, was originally thought to be expressed almost exclusively in the mature nervous and neuroendocrine systems. In the last few years, it was demonstrated, however, that high levels of PENK messenger RNA and PENK-derived peptides are expressed in embryonic mesenchymal tissues during differentiation ...
H, Rosen, A, Krichevsky, R D, Polakiewicz, S, Benzakine, Z, Bar-Shavit   +4 more
openaire   +3 more sources

Poly(ADP-ribosyl)ating enzymes cooperate to coordinate development

Scientific Reports, 2022
The transcriptome is subject to rapid and massive changes during the transition between developmental stages. These changes require tight control to avoid the undesired reactivation of gene expression that is only important for previous developmental ...
Guillaume Bordet, Iaroslava Karpova, Alexei V. Tulin   +2 more
doaj   +1 more source

DNA methylation-free Arabidopsis reveals crucial roles of DNA methylation in regulating gene expression and development

Nature Communications, 2022
Our understanding of the extent of involvement of DNA methylation in genome-wide gene regulation and plant developmental control is incomplete. Here, the authors knock out all five known DNA methyltransferases and show the developmental and gene ...
Li He, Huan Huang, Mariem Bradai, Cheng Zhao, Yin You, Jun Ma, Lun Zhao, Rosa Lozano-Durán, Jian-Kang Zhu   +8 more
doaj   +1 more source

mRNA Cap Methylation in Pluripotency and Differentiation

Cell Reports, 2016
The mRNA cap recruits factors essential for transcript processing and translation initiation. We report that regulated mRNA cap methylation is a feature of embryonic stem cell (ESC) differentiation. Expression of the mRNA cap methyltransferase activating
Laura Grasso, Olga Suska, Lindsay Davidson, Thomas Gonatopoulos-Pournatzis, Ritchie Williamson, Lize Wasmus, Simone Wiedlich, Mark Peggie, Marios P. Stavridis, Victoria H. Cowling   +9 more
doaj   +1 more source

Regulation of Trypanosoma brucei Total and Polysomal mRNA during Development within Its Mammalian Host [PDF]

, 2013
The gene expression of Trypanosoma brucei has been examined extensively in the blood of mammalian hosts and in forms found in the midgut of its arthropod vector, the tsetse fly.
Ivens, A, Pegine Walrad (267013), Capewell, P, Ivens, Alasdair, Terry K Smith, Keith R Matthews, Macgregor, Paula, Matthews, Keith R; id_orcid, Bringaud, F, Bringaud, Frederic, Smith, Terry K., Paul Capewell (137761), Katelyn Fenn (22199), Paula Macgregor, Smith, T, Fenn, K, Paul Capewell, Stephanie Monk, MacGregor, P, Alasdair Ivens (33327), Katelyn Fenn, Keith R. Matthews (199001), Matthews, K, Matthews, Keith R., Frederic Bringaud, Walrad, Pegine, Monk, S, Terry K. Smith (112550), Walrad, P, Stephanie Monk (427018), Matthews, Keith R, Keith R. Matthews, Frederic Bringaud (5655364), Smith, Terry K, Monk, Stephanie, Pegine Walrad, Fenn, Katelyn, Capewell, Paul, Alasdair Ivens, Terry K. Smith, Paula MacGregor (198985)   +40 more
core   +1 more source

Optogenetic Control of Gene Expression in Drosophila. [PDF]

PLoS ONE, 2015
To study the molecular mechanism of complex biological systems, it is important to be able to artificially manipulate gene expression in desired target sites with high precision.
Yick-Bun Chan, Olga V Alekseyenko, Edward A Kravitz   +2 more
doaj   +1 more source

Post-transcriptional gene expression regulation in developmental disorders

, 2021
Gene expression regulation is a set of critical biological processes that give rise to the diversity of cell types across tissues and development stages. Noncoding regions of the genome (intergenic + intronic, >98% of genome) play an important role in these processes, with noncoding genetic variation quantitatively affecting transcriptional activity,
openaire   +2 more sources

Human aldolase C: gene transcriptional regulation and protein functional role [PDF]

, 2011
Aldolase C is the brain-specific aldolase isoenzyme. In the human brain, aldolase C messenger and protein are expressed in a stripe-like pattern in the Purkinje cells of the cerebellum, in the inferior olives and in the Goll and Burdach nuclei of the ...
Serio, Laura
core   +1 more source

Differential timing of gene expression regulation between leptocephali of the two Anguilla eel species in the Sargasso Sea [PDF]

, 2011
The unique life-history characteristics of North Atlantic catadromous eels have long intrigued evolutionary biologists, especially with respect to mechanisms that could explain their persistence as two ecologically very similar but reproductively and ...
Maes, Gregory E., Als, Thomas Damm, Als, Thomas D., Martin Castonguay, Michael M. Hansen, Jérôme St-Cyr, Bernatchez, Louis, Louis Bernatchez, Thomas D. Als, Eric Normandeau, St-Cyr, Jerome, Als, Thomas, Cramb, Gordon, Saint-Cyr, Jérôme, Gordon Cramb, Maes, Gregory, Kalujnaia, S., Hansen, Michael M., Normandeau, Eric, Svetlana Kalujnaia, Hansen, Michael Møller, Kalujnaia, Svetlana, Hansen, Michael, Gregory E. Maes, Castonguay, Martin   +24 more
core   +1 more source