Dynamic expression of chromatin modifiers during developmental transitions in mouse preimplantation embryos [PDF]
, 2015 During mouse preimplantation development, major changes in cell fate are accompanied by extensive alterations of gene expression programs. Embryos first transition from a maternal to zygotic program and subsequently specify the pluripotent and the ...
Peters, Antoine H. F. M. +3 more
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Poly(ADP-ribosyl)ating enzymes cooperate to coordinate development
Scientific Reports, 2022 The transcriptome is subject to rapid and massive changes during the transition between developmental stages. These changes require tight control to avoid the undesired reactivation of gene expression that is only important for previous developmental ...
Guillaume Bordet +2 more
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Nature Communications, 2022 Our understanding of the extent of involvement of DNA methylation in genome-wide gene regulation and plant developmental control is incomplete. Here, the authors knock out all five known DNA methyltransferases and show the developmental and gene ...
Li He +8 more
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mRNA Cap Methylation in Pluripotency and Differentiation
Cell Reports, 2016 The mRNA cap recruits factors essential for transcript processing and translation initiation. We report that regulated mRNA cap methylation is a feature of embryonic stem cell (ESC) differentiation. Expression of the mRNA cap methyltransferase activating
Laura Grasso +9 more
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Transcriptome sequencing and developmental regulation of gene expression in Anopheles aquasalis. [PDF]
PLoS Neglected Tropical Diseases, 2014 BACKGROUND:Anopheles aquasalis is a major malaria vector in coastal areas of South and Central America where it breeds preferentially in brackish water.
André L Costa-da-Silva +12 more
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Functional genomic analysis of developmental control gene action in the embryonic nervous system of "Drosophila" [PDF]
, 2003 In the past two decades, developmental genetic analysis of the molecular control elements involved in early embryonic brain patterning has uncovered the existence of structurally and functionally homologous genes that have comparable, and indeed ...
Montalta-He, Haiqiong
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Optogenetic Control of Gene Expression in Drosophila. [PDF]
PLoS ONE, 2015 To study the molecular mechanism of complex biological systems, it is important to be able to artificially manipulate gene expression in desired target sites with high precision.
Yick-Bun Chan +2 more
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, 2013 Uncoupling protein-3 (UCP3) is a member of the mitochondrial carrier family expressed preferentially in skeletal muscle and heart. It appears to be involved in metabolic handling of fatty acids in a way that minimizes excessive production of reactive ...
Villarroya i Gombau, Francesc +6 more
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Role of cyclic AMP in the control of cell-specific gene expression [PDF]
, 1993 Genes have to be expressed in specific cell types at appropriate times of development dependent on external signals. cAMP signaling occurs in all cells, thus raising the question of how this signal transduction pattern is integrated into mechanisms ...
Boshart, Michael +3 more
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Genome-wide expression profiling of in vivo-derived bloodstream parasite stages and dynamic analysis of mRNA alterations during synchronous differentiation in Trypanosoma brucei [PDF]
, 2009 Background: Trypanosomes undergo extensive developmental changes during their complex life cycle. Crucial among these is the transition between slender and stumpy bloodstream forms and, thereafter, the differentiation from stumpy to tsetse-midgut ...
Ross Alan +22 more
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