Results 1 to 10 of about 1,775,879 (211)

<i>Pseudomonas simiae</i>-induced resistance in barley is subject to pathogen-dependent gene expression regulation and not associated with major changes in the phyllosphere microbiome. [PDF]

Front Microbiol
Sommer A, Bagheri S, Dey S, Knappe C, Wenig M, Heuschmann C, Kublik S, Stempfl T, Schloter M, Vlot AC.   +9 more
europepmc   +3 more sources

Factors and Methods for the Detection of Gene Expression Regulation [PDF]

Biomolecules, 2023
Lingbo Liu, Mengyuan Wang, Qian Li
exaly   +2 more sources

Chronic IL-1 Exposure Attenuates IL-1 Response and Alters Gene Expression Regulation While Maintaining Therapeutic Sensitivity in BCa Cell Lines. [PDF]

Int J Mol Sci
Falah R, Dhar R, Yamauchi S, Bautista M, Kanchwala M, Yan L, Raju D, Xu L, Reliford K, Nawas A, Ali S, Fang J, Olaleye O, Tera J, Abdelaziz R, Kanakala R, Sudunagunta A, Eedarapali S, Burr E, Mansoor BS, Roos N, Diep S, Afaq H, Rajesh NP, Manohar S, Odikpo J, Jain AK, Xuan Z, Xing C, Delk NA.   +29 more
europepmc   +2 more sources

A minimal bile salt excretory pump promoter allows bile acid-driven physiological regulation of transgene expression from a gene therapy vector

Cell & Bioscience, 2022
Background Bile acid (BA) homeostasis is mainly regulated by bile salt excretory pump (BSEP), a hepatocyte transporter that transfers BAs to the bile.
Javier Martínez-García, Manuela Molina, Leticia Odriozola, Angie Molina, Gloria González-Aseguinolaza, Nicholas D. Weber, Cristian Smerdou   +6 more
doaj   +1 more source

The role of CPEB family proteins in the nervous system function in the norm and pathology

Cell & Bioscience, 2021
Posttranscriptional gene regulation includes mRNA transport, localization, translation, and regulation of mRNA stability. CPEB (cytoplasmic polyadenylation element binding) family proteins bind to specific sites within the 3′-untranslated region and ...
Eugene Kozlov, Yulii V. Shidlovskii, Rudolf Gilmutdinov, Paul Schedl, Mariya Zhukova   +4 more
doaj   +1 more source

Idiotype vaccines produced with a non-cytopathic alphavirus self-amplifying RNA vector induce antitumor responses in a murine model of B-cell lymphoma

Scientific Reports, 2021
A promising therapy for patients with B-cell lymphoma is based on vaccination with idiotype monoclonal antibodies (mAbs). Since idiotypes are different in each tumor, a personalized vaccine has to be produced for each patient.
Erkuden Casales, Eva Martisova, Helena Villanueva, Ascensión López Díaz de Cerio, Susana Inoges, Noelia Silva-Pilipich, María Cristina Ballesteros-Briones, Alejandro Aranda, Jaione Bezunartea, Maurizio Bendandi, Fernando Pastor, Cristian Smerdou   +11 more
doaj   +1 more source

Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence

Nature Communications, 2020
Here, the authors show that the topoisomerase 1-DNA covalent cleavage complex plays a critical role in mediating cytoplasmic chromatin fragments recognition by cyclic GMP-AMP synthase during senescence.
Bo Zhao, Pingyu Liu, Takeshi Fukumoto, Timothy Nacarelli, Nail Fatkhutdinov, Shuai Wu, Jianhuang Lin, Katherine M. Aird, Hsin-Yao Tang, Qin Liu, David W. Speicher, Rugang Zhang   +11 more
doaj   +1 more source

Localization and Functional Roles of Components of the Translation Apparatus in the Eukaryotic Cell Nucleus

Cells, 2021
Components of the translation apparatus, including ribosomal proteins, have been found in cell nuclei in various organisms. Components of the translation apparatus are involved in various nuclear processes, particularly those associated with genome ...
Zaur M. Kachaev, Sergey D. Ivashchenko, Eugene N. Kozlov, Lyubov A. Lebedeva, Yulii V. Shidlovskii   +4 more
doaj   +1 more source

Brassinosteroid-Regulated Gene Expression [PDF]

Plant Physiology, 2002
Abstract Major brassinosteroid (BR) effects such as BR-induced growth are mediated through genomic pathways because RNA synthesis inhibitors and protein synthesis inhibitors interfere with these processes. A limited number of BR-regulated genes have been identified hitherto. The majority of genes (such as BRU1, CycD3,Lin6, OPR3, and TRIP-
Altmann, Thomas, Müssig, Carsten, Fischer, Sabine   +2 more
openaire   +4 more sources

Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function

Nature Communications, 2020
ATRX is an RNA binding protein that mediates targeting of polycomb repressive complex 2 (PRC2) to genomic sites. Here the authors identify the RNA binding region and show that the RNA binding is required for ATRX localization and for its recruitment of ...
Wenqing Ren, Nicole Medeiros, Robert Warneford-Thomson, Phillip Wulfridge, Qingqing Yan, Joyce Bian, Simone Sidoli, Benjamin A. Garcia, Emmanuel Skordalakes, Eric Joyce, Roberto Bonasio, Kavitha Sarma   +11 more
doaj   +1 more source