A system to enrich for primitive streak-derivatives, definitive endoderm and mesoderm, from pluripotent cells in culture. [PDF]
PLoS ONE, 2012 Two lineages of endoderm develop during mammalian embryogenesis, the primitive endoderm in the pre-implantation blastocyst and the definitive endoderm at gastrulation.
Svetlana Vassilieva +6 more
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Stem Cell Research, 2018 Liver organogenesis requires complex cell-cell interactions between hepatic endoderm cells and adjacent cell niches. Endothelial cells are key players for endoderm hepatic fate decision. We previously demonstrated that the endothelial cell niche promotes
Songyan Han +5 more
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GATA6 is essential for endoderm formation from human pluripotent stem cells
Biology Open, 2017 Protocols have been established that direct differentiation of human pluripotent stem cells into a variety of cell types, including the endoderm and its derivatives. This model of differentiation has been useful for investigating the molecular mechanisms
J. B. Fisher +3 more
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The Ecto-Endodermal Boundary in the Oral and Pharyngeal Mucosa: A Narrative Review [PDF]
LifeIntroduction: The ecto-endodermal boundary in the human oral cavity remains debated. Rather than a distinct line, this transition forms a complex interface, especially in the developing mouth and pharynx.
Rogier Schipperheijn +2 more
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Endoderm and heart development [PDF]
Developmental Dynamics, 2000 Since the first half of the 20th century, experimental embryologists have noted a relationship between endoderm cells and the development of cardiac tissue from mesoderm. During the past decade, the accumulation of evidence for an obligatory interaction between endoderm and mesoderm during the specification and terminal differentiation of myocardial ...
John Lough, Y Sugi
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The lncRNA DEANR1 Facilitates Human Endoderm Differentiation by Activating FOXA2 Expression
Cell Reports, 2015 Long non-coding RNAs (lncRNAs) regulate diverse biological processes, including cell lineage specification. Here, we report transcriptome profiling of human endoderm and pancreatic cell lineages using purified cell populations.
Wei Jiang +4 more
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Cell Reports, 2016 Long noncoding RNAs (lncRNAs) exhibit diverse functions, including regulation of development. Here, we combine genome-wide mapping of SMAD3 occupancy with expression analysis to identify lncRNAs induced by activin signaling during endoderm ...
Kaveh Daneshvar +13 more
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Induced Pluripotent Stem Cells as a Tool to Decipher the Normal and Abnormal Development of the Esophagus and Trachea from Normal Morphogenesis to Esophageal Atresia, Tracheomalacia, and Laryngo–Tracheal Clefts [PDF]
CellsThe development of the esophagus and trachea following the septation of the anterior foregut is a highly regulated process involving bidirectional communication between the endoderm and mesoderm.
Yuxuan Zhang +3 more
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Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids [PDF]
Advanced ScienceThe human heart, originating from the splanchnic mesoderm, is the first functional organ to develop, co‐evolving with the foregut endoderm through reciprocal signaling.
Plansky Hoang +12 more
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Aptly Named Visceral Endoderm [PDF]
Developmental Cell, 2008 The very early mouse embryo is initially covered by a layer of cells called visceral endoderm that despite its name (visceral means associated with internal organs) was only thought to give rise to extraembryonic structures. Now, in this issue of Developmental Cell, Kwon et al. (2008) show unexpectedly that a significant population of visceral endoderm
Stern, Claudio D.
openaire +4 more sources