A system to enrich for primitive streak-derivatives, definitive endoderm and mesoderm, from pluripotent cells in culture. [PDF]
PLoS ONE, 2012 Two lineages of endoderm develop during mammalian embryogenesis, the primitive endoderm in the pre-implantation blastocyst and the definitive endoderm at gastrulation.
Svetlana Vassilieva +6 more
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StemBook, 2008 In this chapter I focus on the emergence of endoderm, the origin of these cells and their organization in space. I also discuss the molecular events that lead to endoderm formation and how endoderm can be molecularly defined.
Grapin-Botton, Anne
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Induced Pluripotent Stem Cells as a Tool to Decipher the Normal and Abnormal Development of the Esophagus and Trachea from Normal Morphogenesis to Esophageal Atresia, Tracheomalacia, and Laryngo–Tracheal Clefts [PDF]
CellsThe development of the esophagus and trachea following the septation of the anterior foregut is a highly regulated process involving bidirectional communication between the endoderm and mesoderm.
Yuxuan Zhang +3 more
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Aptly Named Visceral Endoderm [PDF]
Developmental Cell, 2008 The very early mouse embryo is initially covered by a layer of cells called visceral endoderm that despite its name (visceral means associated with internal organs) was only thought to give rise to extraembryonic structures. Now, in this issue of Developmental Cell, Kwon et al. (2008) show unexpectedly that a significant population of visceral endoderm
Stern, Claudio D.
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Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids [PDF]
Advanced ScienceThe human heart, originating from the splanchnic mesoderm, is the first functional organ to develop, co‐evolving with the foregut endoderm through reciprocal signaling.
Plansky Hoang +12 more
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Differentiation of extraembryonic endoderm stem cell lines and parietal endoderm into visceral endoderm: the art of XEN cells [PDF]
, 2012 The extraembryonic endoderm of mammals is essential for nutritive support of the foetus and patterning of the early embryo. Visceral and parietal endoderm are major subtypes of this lineage with the former exhibiting most, if not all, of the embryonic patterning properties. Extraembryonic endoderm (XEN) cell lines derived from the primitive endoderm of
Paca, Agnieszka Maria
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A role for planar cell polarity during early endoderm morphogenesis [PDF]
Biology Open, 2017 The zebrafish endoderm begins to develop at gastrulation stages as a monolayer of cells. The behaviour of the endoderm during gastrulation stages is well understood.
Lee B. Miles +3 more
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Retinoic Acid and the Development of the Endoderm [PDF]
Journal of Developmental Biology, 2015 Retinoic acid (RA) is an important signaling molecule in the development of the endoderm and an important molecule in protocols used to generate endodermal cell types from stem cells.
Gregory M. Kelly, Thomas A. Drysdale
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A novel method for generating induced pluripotent stem cell (iPSC)-derived alveolar organoids: a comparison of their ability depending on iPSC origin [PDF]
Organoid, 2023 Background Alveolar organoids may be useful tools in drug discovery for lung diseases, such as chronic obstructive pulmonary disease, and for studying the effects of respiratory viruses, such as severe acute respiratory syndrome coronavirus 2.
Min Jae Lim, Ayoung Jo, Sung-Won Kim
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Cells, 2021 The endoderm, differentiated from human induced pluripotent stem cells (iPSCs), can differentiate into the small intestine and liver, which are vital for drug absorption and metabolism.
Shimeng Qiu +6 more
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