Results 11 to 20 of about 95,300 (301)
Inhibition of EZH2 Promotes Human Embryonic Stem Cell Differentiation into Mesoderm by Reducing H3K27me3 [PDF]
Mesoderm derived from human embryonic stem cells (hESCs) is a major source of the mesenchymal stem/stromal cells (MSCs) that can differentiate into osteoblasts and chondrocytes for tissue regeneration.
Yongxin Yu +6 more
doaj +4 more sources
Fate mapping identifies the origin of SHF/AHF progenitors in the chick primitive streak [PDF]
Heart development depends on the spatio-temporally regulated contribution of progenitor cells from the primary, secondary and anterior heart fields. Primary heart field (PHF) cells are first recruited to form a linear heart tube; later, they contribute ...
Camp, E. +2 more
core +22 more sources
Hox Genes Regulate Muscle Founder Cell Pattern Autonomously and Regulate Morphogenesis Through Motor Neurons [PDF]
The differentiation of myoblasts to form functional muscle fibers is a consequence of interactions between the mesoderm and ectoderm. The authors examine the role of segment identity in directing these interactions by studying the role of Hox genes in ...
Dutta, Devkanya +4 more
core +1 more source
Distinct modes of floor plate induction in the chick embryo [PDF]
To begin to reconcile models of floor plate formation in the vertebrate neural tube, we have performed experiments aimed at understanding the development of the early floor plate in the chick embryo. Using real-time analyses of cell behaviour, we provide
Fraser, Scott +4 more
core +1 more source
The occipital lateral plate mesoderm is a novel source for vertebrate neck musculature [PDF]
In vertebrates, body musculature originates from somites, whereas head muscles originate from the cranial mesoderm. Neck muscles are located in the transition between these regions.
Christ, B. +9 more
core +1 more source
Summary: Attempts to generate functional blood cells from human pluripotent stem cells (hPSCs) remain largely unsuccessful, mainly due to the lack of understanding of the regulatory network of human hematopoiesis.
Yu Wang +13 more
doaj +1 more source
Functionally distinct roles for T and Tbx6 during mouse development
The mouse T-box transcription factors T and Tbx6 are co-expressed in the primitive streak and have unique domains of expression; T is expressed in the notochord, while Tbx6 is expressed in the presomitic mesoderm.
Amy K. Wehn +4 more
doaj +1 more source
The emergence of Pax7-expressing muscle stem cells during vertebrate head muscle development [PDF]
Pax7 expressing muscle stem cells accompany all skeletal muscles in the body and in healthy individuals, efficiently repair muscle after injury. Currently, the in vitro manipulation and culture of these cells is still in its infancy, yet muscle stem ...
Anna eNoble +9 more
core +2 more sources
Evidence for a Role of the Lateral Ectoderm in Drosophila Mesoderm Invagination
The folding of two-dimensional epithelial sheets into specific three-dimensional structures is a fundamental tissue construction mechanism in animal development.
Hanqing Guo, Shicheng Huang, Bing He
doaj +1 more source
Cohesin is a multiprotein complex made up of core subunits Smc1, Smc3, and Rad21, and either Stag1 or Stag2. Normal haematopoietic development relies on crucial functions of cohesin in cell division and regulation of gene expression via three-dimensional
Sarada Ketharnathan +3 more
doaj +1 more source

