Results 21 to 30 of about 64,865 (357)
Summary: Attempts to generate functional blood cells from human pluripotent stem cells (hPSCs) remain largely unsuccessful, mainly due to the lack of understanding of the regulatory network of human hematopoiesis.
Yu Wang +13 more
doaj +1 more source
Normal levels of p27Xic1 are necessary for somite segmentation and determining pronephric organ size [PDF]
The Xenopus laevis cyclin dependent kinase inhibitor p27Xic1 has been shown to be involved in exit from the cell cycle and differentiation of cells into a quiescent state in the nervous system, muscle tissue, heart and retina.
Collins, R.J. +7 more
core +1 more source
Functionally distinct roles for T and Tbx6 during mouse development
The mouse T-box transcription factors T and Tbx6 are co-expressed in the primitive streak and have unique domains of expression; T is expressed in the notochord, while Tbx6 is expressed in the presomitic mesoderm.
Amy K. Wehn +4 more
doaj +1 more source
Fate mapping identifies the origin of SHF/AHF progenitors in the chick primitive streak [PDF]
Heart development depends on the spatio-temporally regulated contribution of progenitor cells from the primary, secondary and anterior heart fields. Primary heart field (PHF) cells are first recruited to form a linear heart tube; later, they contribute ...
Susanne Dietrich +6 more
core +1 more source
The emergence of Pax7-expressing muscle stem cells during vertebrate head muscle development [PDF]
Pax7 expressing muscle stem cells accompany all skeletal muscles in the body and in healthy individuals, efficiently repair muscle after injury. Currently, the in vitro manipulation and culture of these cells is still in its infancy, yet muscle stem ...
Erika C. Jorge +23 more
core +1 more source
Evidence for a Role of the Lateral Ectoderm in Drosophila Mesoderm Invagination
The folding of two-dimensional epithelial sheets into specific three-dimensional structures is a fundamental tissue construction mechanism in animal development.
Hanqing Guo, Shicheng Huang, Bing He
doaj +1 more source
A system to enrich for primitive streak-derivatives, definitive endoderm and mesoderm, from pluripotent cells in culture [PDF]
Two lineages of endoderm develop during mammalian embryogenesis, the primitive endoderm in the pre-implantation blastocyst and the definitive endoderm at gastrulation.
Lau, KX +27 more
core +2 more sources
Fibroepithelial Polyp Originating from the Nasal Septum
Fibroepithelial polyp (FEP) is a rare clinical condition of mesodermal origin, covered usually by squamous epithelium, originating most frequently from the skin, genitourinary and lower respiratory tract.
Marko Stoiljkov, Aleksandar Perić
doaj +1 more source
Early patterning and specification of cardiac progenitors in gastrulating mesoderm
Mammalian heart development requires precise allocation of cardiac progenitors. The existence of a multipotent progenitor for all anatomic and cellular components of the heart has been predicted but its identity and contribution to the two cardiac ...
W Patrick Devine +4 more
doaj +1 more source

