Results 21 to 30 of about 52,080 (250)

Inhibition of IKK/NF-κB Signaling Enhances Differentiation of Mesenchymal Stromal Cells from Human Embryonic Stem Cells

open access: yesStem Cell Reports, 2016
Embryonic stem cell-derived mesenchymal stromal cells (MSCs; also known as mesenchymal stem cells) represent a promising source for bone regenerative medicine.
Peng Deng   +4 more
doaj   +1 more source

LGR4, Not LGR5, Enhances hPSC Hematopoiesis by Facilitating Mesoderm Induction via TGF-Beta Signaling Activation

open access: yesCell Reports, 2020
Summary: Attempts to generate functional blood cells from human pluripotent stem cells (hPSCs) remain largely unsuccessful, mainly due to the lack of understanding of the regulatory network of human hematopoiesis.
Yu Wang   +13 more
doaj   +1 more source

The lateral plate mesoderm

open access: yesDevelopment, 2020
ABSTRACTThe lateral plate mesoderm (LPM) forms the progenitor cells that constitute the heart and cardiovascular system, blood, kidneys, smooth muscle lineage and limb skeleton in the developing vertebrate embryo. Despite this central role in development and evolution, the LPM remains challenging to study and to delineate, owing to its lineage ...
Karin D. Prummel   +2 more
openaire   +3 more sources

Functionally distinct roles for T and Tbx6 during mouse development

open access: yesBiology Open, 2020
The mouse T-box transcription factors T and Tbx6 are co-expressed in the primitive streak and have unique domains of expression; T is expressed in the notochord, while Tbx6 is expressed in the presomitic mesoderm.
Amy K. Wehn   +4 more
doaj   +1 more source

Fibroepithelial Polyp Originating from the Nasal Septum

open access: yesTurkish Archives of Otorhinolaryngology, 2019
Fibroepithelial polyp (FEP) is a rare clinical condition of mesodermal origin, covered usually by squamous epithelium, originating most frequently from the skin, genitourinary and lower respiratory tract.
Marko Stoiljkov, Aleksandar Perić
doaj   +1 more source

Early patterning and specification of cardiac progenitors in gastrulating mesoderm

open access: yeseLife, 2014
Mammalian heart development requires precise allocation of cardiac progenitors. The existence of a multipotent progenitor for all anatomic and cellular components of the heart has been predicted but its identity and contribution to the two cardiac ...
W Patrick Devine   +4 more
doaj   +1 more source

Cohesin Components Stag1 and Stag2 Differentially Influence Haematopoietic Mesoderm Development in Zebrafish Embryos

open access: yesFrontiers in Cell and Developmental Biology, 2020
Cohesin is a multiprotein complex made up of core subunits Smc1, Smc3, and Rad21, and either Stag1 or Stag2. Normal haematopoietic development relies on crucial functions of cohesin in cell division and regulation of gene expression via three-dimensional
Sarada Ketharnathan   +3 more
doaj   +1 more source

Gene profiling of head mesoderm in early zebrafish development: insights into the evolution of cranial mesoderm

open access: yesEvoDevo, 2019
Background The evolution of the head was one of the key events that marked the transition from invertebrates to vertebrates. With the emergence of structures such as eyes and jaws, vertebrates evolved an active and predatory life style and radiated into ...
Huijia Wang   +2 more
doaj   +1 more source

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