Results 141 to 150 of about 1,157,389 (344)

Conceptual Breakthroughs In Developmental Biology [PDF]

, 1998
Gilbert, Scott F.
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Induction of host genes by nested genes during C. elegans development

iScience
Summary: Embryonic development relies on tightly controlled gene expression. In this study, we analyzed the transcriptional effect during C. elegans development of a striking genomic topology, the opposite nested configuration, where a gene is located in
Fabien Soulavie, Carole Couillault, Matéo Melki, Khulganaa Buyannemekh, Antoine Barrière, Paul Villoutreix, Vincent Bertrand   +6 more
doaj   +1 more source

An interview with Margaret Buckingham: President of the French Society of Developmental Biology [PDF]

, 2011
Eva Amsen
openalex   +1 more source

USSR Space Life Sciences Digest, issue 29 [PDF]

This is the twenty-ninth issue of NASA's Space Life Sciences Digest. It is a double issue covering two issues of the Soviet Space Biology and Aerospace Medicine Journal.
Rowe, Joseph, Stone, Lydia Razran, Teeter, Ronald   +2 more
core   +1 more source

From Development To Evolution: The Re-Establishment Of The Alexander Kowalevsky Medal [PDF]

, 2002
The Saint Petersburg Society of Naturalists has reinstated the Alexander O. Kowalevsky Medal. This article announces the winners of the first medals and briefly reviews the achievements of A.O.
Gilbert, Scott F., Mikhailov, A. T.
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Developmental Biology [PDF]

Archives of Pediatrics & Adolescent Medicine, 1969
openaire   +3 more sources

Protocol for identifying protein synthesis activity in specific cell types of the testicular lumen

STAR Protocols
Summary: Protein synthesis could control spermatogenic cell fate transitions. Here, we present a protocol for visualization and quantification of newly synthesized proteins by click-chemistry-based immunofluorescence within specific spermatogenic cell ...
Dingfeng Zou, Kai Li, Yan Lu, Wei Yan, Wei Song   +4 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source