Results 151 to 160 of about 541,795 (259)

Pathway to Independence: the future of developmental biology.

Development, 2023
Agarwal P, Cadart C, Fort L, Gahan J, Greenspan L, Juan T, Kameneva P, Miao Y.   +7 more
europepmc   +1 more source

Marine animal evolutionary developmental biology-Advances through technology development. [PDF]

Evol Appl, 2023
Stracke K, Hejnol A.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Sex-specific functional evolution of Dmrt1 in African clawed frogs (Xenopus), and the importance of genetic tipping points in developmental biology. [PDF]

PLoS Genet
Kukoly LM, Porter SR, Jordan DC, Murphy HA, Knytl M, Shaidani N, Thomas WR, Anderson C, Dworkin I, Horb ME, Evans BJ.   +10 more
europepmc   +1 more source

Microfluidics and Organoids, the Power Couple of Developmental Biology and Oncology Studies. [PDF]

Int J Mol Sci, 2023
Hetzel LA, Ali A, Corbo V, Hankemeier T.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Embryological Divergence and Molecular Mechanisms in Thoracic and Abdominal Aortic Aneurysms: Bridging Developmental Biology and Clinical Insights. [PDF]

Biomolecules
Van Hemelrijck M, Risteski P, Rings L, Milojevic M, Rodríguez Cetina Biefer H, Dzemali O.   +5 more
europepmc   +1 more source

A new era of stem cell and developmental biology: from blastoids to synthetic embryos and beyond. [PDF]

Exp Mol Med, 2023
Kim Y, Kim I, Shin K.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

The Neural Tube CURE: Engaging undergraduate students in a relevant developmental biology research course. [PDF]

Dev Biol
Kakebeen AD, Fandel JY, Niswander LA.
europepmc   +1 more source