Results 11 to 20 of about 35,406 (217)

Non-muscle myosin II drives critical steps of nematocyst morphogenesis

iScience, 2023
Summary: Nematocysts are generated by secretion of proteins into a post-Golgi compartment. They consist of a capsule that elongates into a long tube, which is coiled inside the capsule matrix and expelled during its nano-second discharge deployed for ...
Niharika Garg, Urška Knez Štibler, Björn Eismann, Moritz Mercker, Bruno Gideon Bergheim, Anna Linn, Patrizia Tuchscherer, Ulrike Engel, Stefan Redl, Anna Marciniak-Czochra, Thomas W. Holstein, Michael W. Hess, Suat Özbek   +12 more
doaj   +1 more source

X-Linked Huwe1 Is Essential for Oocyte Maturation and Preimplantation Embryo Development

iScience, 2020
Summary: HUWE1 is a HECT-domain ubiquitin E3 ligase expressed in various tissues. Although HUWE1 is known to promote degradation of the tumor suppressor p53, given a growing list of its substrates, in vivo functions of HUWE1 remain elusive.
Alaa A. Eisa, Scott Bang, Katherine J. Crawford, Emily M. Murphy, William W. Feng, Souvik Dey, Wendy Wells, Ning Kon, Wei Gu, Lisa M. Mehlmann, Srinivasan Vijayaraghavan, Manabu Kurokawa   +11 more
doaj   +1 more source

Protocol for isolation and ATAC-seq library construction of zebrafish red blood cells

STAR Protocols, 2022
Summary: Understanding chromatin dynamics in red blood cells (RBCs) is critical for exploring the differentiation process and homeostasis maintenance during erythropoiesis.
Yanyan Ding, Feng Liu
doaj   +1 more source

Developmental Biology in Cyanobacteria

Life, 2019
Filamentous, heterocyst-forming cyanobacteria are phototrophic multicellular organisms in which N2-fixing heterocysts and CO2-fixing vegetative cells exchange regulators and nutrients [...]
Antonia Herrero, Enrique Flores
doaj   +1 more source

Counteractive and cooperative actions of muscle β-catenin and CaV1.1 during early neuromuscular synapse formation

iScience, 2022
Summary: Activity-dependent calcium signals in developing muscle play a crucial role in neuromuscular junction (NMJ) formation. However, its downstream effectors and interactions with other regulators of pre- and postsynaptic differentiation are poorly ...
Mehmet Mahsum Kaplan, Bernhard E. Flucher   +1 more
doaj   +1 more source

Increasing Diversity in Developmental Biology

Frontiers in Sociology, 2022
The demographic profile of the scientific and biomedical workforce in the United States does not reflect the population at large (https://ncses.nsf.gov/pubs/nsf21321/data-tables; www.census.gov), raising concerns that there will be too few trained ...
Graciela A. Unguez, Karen L. Bennett, Carmen Domingo, Ida Chow   +3 more
doaj   +1 more source

Single cell expression analysis of primate-specific retroviruses-derived HPAT lincRNAs in viable human blastocysts identifies embryonic cells co-expressing genetic markers of multiple lineages

Heliyon, 2018
Chromosome instability and aneuploidies occur very frequently in human embryos, impairing proper embryogenesis and leading to cell cycle arrest, loss of cell viability, and developmental failures in 50–80% of cleavage-stage embryos.
Gennadi Glinsky, Jens Durruthy-Durruthy, Mark Wossidlo, Edward J. Grow, Jason L. Weirather, Kin Fai Au, Joanna Wysocka, Vittorio Sebastiano   +7 more
doaj   +1 more source

Sox9 regulates melanocytic fate decision of adult hair follicle stem cells

iScience, 2023
Summary: The bulge of hair follicles harbors Nestin+ (neural crest like) stem cells, which exhibit the potential to generate various cell types including melanocytes.
Isabel Stüfchen, Felix Beyer, Sebastian Staebler, Stefan Fischer, Melanie Kappelmann, Ruth Beckervordersandforth, Anja K. Bosserhoff   +6 more
doaj   +1 more source

Apicosome: Newly identified cell-type-specific organelle in mouse cochlear and vestibular hair cells

iScience, 2023
Summary: Cochlear and vestibular hair cells are highly specialized sensory receptors for hearing and balance. Here, we report a serendipitous identification of a hair-cell-specific organelle in neonatal mouse inner ear, which we name “apicosome.” The ...
Xiaofen Li, Qirui Zhao, Xiaojie Yu, Wenhan Cao, Yingyi Zhang, Wanying Feng, Liwen Jiang, David Z. He, Robert Z. Qi, Pingbo Huang   +9 more
doaj   +1 more source

Seed mineral reserves and vigour of Bambara groundnut (Vigna subterranea L.) landraces differing in seed coat colour

Heliyon, 2019
A newly emerged seedling, given light and water, but no external source of minerals, uses its internal mineral nutrient reserves effectively for an early establishment.
T. Mandizvo, A.O. Odindo
doaj   +1 more source