Results 11 to 20 of about 525,333 (255)

Non-muscle myosin II drives critical steps of nematocyst morphogenesis

iScience, 2023
Summary: Nematocysts are generated by secretion of proteins into a post-Golgi compartment. They consist of a capsule that elongates into a long tube, which is coiled inside the capsule matrix and expelled during its nano-second discharge deployed for ...
Niharika Garg, Urška Knez Štibler, Björn Eismann, Moritz Mercker, Bruno Gideon Bergheim, Anna Linn, Patrizia Tuchscherer, Ulrike Engel, Stefan Redl, Anna Marciniak-Czochra, Thomas W. Holstein, Michael W. Hess, Suat Özbek   +12 more
doaj   +1 more source

Acknowledgement to Reviewers of Journal of Developmental Biology in 2018

Journal of Developmental Biology, 2019
Rigorous peer-review is the corner-stone of high-quality academic publishing [...]
Journal of Developmental Biology Editorial Office
doaj   +1 more source

A lncRNA perspective into (re)building the heart

Frontiers in Cell and Developmental Biology, 2016
Our conception of the human genome, long focused on the 2% that codes for proteins, has profoundly changed since its first draft assembly in 2001. Since then, an unanticipatedly expansive functionality and convolution has been attributed to the majority ...
Stefan Frank, Aitor Aguirre, Laboratory for Developmental and Regenerative RNA Biology, Laboratory for Developmental and Regenerative RNA Biology, Laboratory for Developmental and Regenerative RNA Biology   +4 more
doaj   +1 more source

X-Linked Huwe1 Is Essential for Oocyte Maturation and Preimplantation Embryo Development

iScience, 2020
Summary: HUWE1 is a HECT-domain ubiquitin E3 ligase expressed in various tissues. Although HUWE1 is known to promote degradation of the tumor suppressor p53, given a growing list of its substrates, in vivo functions of HUWE1 remain elusive.
Alaa A. Eisa, Scott Bang, Katherine J. Crawford, Emily M. Murphy, William W. Feng, Souvik Dey, Wendy Wells, Ning Kon, Wei Gu, Lisa M. Mehlmann, Srinivasan Vijayaraghavan, Manabu Kurokawa   +11 more
doaj   +1 more source

Acknowledgement to Reviewers of Journal of Developmental Biology in 2015

Journal of Developmental Biology, 2016
The editors of Journal of Developmental Biology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015. [...]
Journal of Developmental Biology Editorial Office
doaj   +1 more source

Protocol for isolation and ATAC-seq library construction of zebrafish red blood cells

STAR Protocols, 2022
Summary: Understanding chromatin dynamics in red blood cells (RBCs) is critical for exploring the differentiation process and homeostasis maintenance during erythropoiesis.
Yanyan Ding, Feng Liu
doaj   +1 more source

Adamts18 modulates the development of the aortic arch and common carotid artery

iScience, 2021
Summary: Members of a disintegrin and metalloproteinases with thrombospondin motif (ADAMTS) family have been implicated in various vascular diseases. However, their functional roles in early embryonic vascular development are unknown.
Shuai Ye, Ning Yang, Tiantian Lu, Taojing Wu, Liya Wang, Yi-Hsuan Pan, Xiaohua Cao, Xiaobing Yuan, Thomas Wisniewski, Suying Dang, Wei Zhang   +10 more
doaj   +1 more source

An ATX-LPA6-Gα13-ROCK axis shapes and maintains caudal vein plexus in zebrafish

iScience, 2021
Summary: Lysophosphatidic acid (LPA) is a potential regulator of vascular formation derived from blood. In this study, we utilized zebrafish as a model organism to monitor the blood vessel formation in detail.
Ryohei Okasato, Kuniyuki Kano, Ryoji Kise, Asuka Inoue, Shigetomo Fukuhara, Junken Aoki   +5 more
doaj   +1 more source

Counteractive and cooperative actions of muscle β-catenin and CaV1.1 during early neuromuscular synapse formation

iScience, 2022
Summary: Activity-dependent calcium signals in developing muscle play a crucial role in neuromuscular junction (NMJ) formation. However, its downstream effectors and interactions with other regulators of pre- and postsynaptic differentiation are poorly ...
Mehmet Mahsum Kaplan, Bernhard E. Flucher   +1 more
doaj   +1 more source

Single cell expression analysis of primate-specific retroviruses-derived HPAT lincRNAs in viable human blastocysts identifies embryonic cells co-expressing genetic markers of multiple lineages

Heliyon, 2018
Chromosome instability and aneuploidies occur very frequently in human embryos, impairing proper embryogenesis and leading to cell cycle arrest, loss of cell viability, and developmental failures in 50–80% of cleavage-stage embryos.
Gennadi Glinsky, Jens Durruthy-Durruthy, Mark Wossidlo, Edward J. Grow, Jason L. Weirather, Kin Fai Au, Joanna Wysocka, Vittorio Sebastiano   +7 more
doaj   +1 more source