Results 231 to 240 of about 2,742,900 (350)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Editorial: 10 years of Frontiers in cell and developmental biology: past discoveries, current challenges and future perspectives. [PDF]

Front Cell Dev Biol
Fisher AG.
europepmc   +1 more source

The revolutionary developmental biology of Wilhelm His, Sr. [PDF]

Biol Rev Camb Philos Soc, 2022
Richardson MK, Keuck G.
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

On the evolutionary developmental biology of the cell. [PDF]

Trends Genet
Babonis LS.
europepmc   +1 more source

Reflections on the past, present and future of developmental biology. [PDF]

Dev Biol, 2022
Stern CD.
europepmc   +1 more source

Computer modeling in developmental biology: growing today, essential tomorrow

Development, 2017
J. Sharpe
semanticscholar   +1 more source

Bringing Developmental Biology to Life on the Web

, 2008
Louisa A. Stark
openalex   +1 more source

Charles Darwin and the Origins of Plant Evolutionary Developmental Biology [PDF]

, 2011
William E. Friedman, Pamela K. Diggle
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source