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Astrocyte heterogeneity in brain metastases
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
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From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Pluripotency of a founding field: rebranding developmental biology.
Rogers CD +49 more
europepmc +1 more source
Neurotoxin-Derived Optical Probes for Elucidating Molecular and Developmental Biology of Neurons and Synaptic Connections : Toxin-Derived Optical Probes for Neuroimaging. [PDF]
Bijjam R +5 more
europepmc +1 more source
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The diversification of developmental biology
Studies in History and Philosophy of Science Part C:Studies in History and Philosophy of Biological and Biomedical Sciences, 2015In the 1960s, "developmental biology" became the dominant term to describe some of the research that had previously been included under the rubrics of embryology, growth, morphology, and physiology. As scientific societies formed under this new label, a new discipline took shape.
Michael Dietrich, Nathan Crowe
exaly +3 more sources
Disability and developmental biology
Development, 2023ABSTRACT Disabled scientists face tremendous barriers to entry into, and progression within, a scientific career, remaining immensely under-represented at every career stage. Disability inclusivity drives in science are increasingly prevalent, but few data are available from the developmental biology community specifically.
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From Developmental Biology to Developmental Toxicology
Annals of the New York Academy of Sciences, 2000Abstract: Progress derived from the human genome project will have tremendous impact on toxicology. Questions concerning genetic susceptibility or resistance to toxic compound exposure and the dissection of the molecular mechanisms involved will be at the forefront of future toxicological research.
BALLING, Rudi, Hrabe de Angelis, M.
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Developmental Biology of Zebrafish
Annals of the New York Academy of Sciences, 2004Abstract: The biology and genetics of zebrafish has become a very popular system in developmental biology especially because of their suitability for genetics and the transparent embryo of this small tropical fish. Studies reported briefly here demonstrate that one can use gene expression in the zebrafish embryo to find new components of important and
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DEVELOPMENTAL BIOLOGY OF HEMATOPOIESIS
Hematology/Oncology Clinics of North America, 1997Hematopoietic stem cells are at the top of a hierarchy that regulates the generation of a vast repertoire of blood cells during the lifetime of a vertebrate. Recent experiments, using a vast variety of embryonic systems, shed new light on the origin of stem cells and the genes that function to regulate and maintain hematopoietic differentiation ...
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