Results 51 to 60 of about 1,092,027 (335)
Non-muscle myosin II drives critical steps of nematocyst morphogenesis
iScience, 2023 Summary: Nematocysts are generated by secretion of proteins into a post-Golgi compartment. They consist of a capsule that elongates into a long tube, which is coiled inside the capsule matrix and expelled during its nano-second discharge deployed for ...
Niharika Garg +12 more
doaj
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Mathematical models in Developmental Biology [PDF]
, 2016 We will introduce some of the mathematical modeling tools that have been introduced in the field of Developmental Biology, focusing in specific problems in embryogenesis.
Calvo Yagüe, Juan
core
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
X-Linked Huwe1 Is Essential for Oocyte Maturation and Preimplantation Embryo Development
iScience, 2020 Summary: HUWE1 is a HECT-domain ubiquitin E3 ligase expressed in various tissues. Although HUWE1 is known to promote degradation of the tumor suppressor p53, given a growing list of its substrates, in vivo functions of HUWE1 remain elusive.
Alaa A. Eisa +11 more
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Protocol for isolation and ATAC-seq library construction of zebrafish red blood cells
STAR Protocols, 2022 Summary: Understanding chromatin dynamics in red blood cells (RBCs) is critical for exploring the differentiation process and homeostasis maintenance during erythropoiesis.
Yanyan Ding, Feng Liu
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FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Pycnogonida developmental biology [PDF]
ArthropodsThe term anamorphic development is used to describe arthropods which add segments throughout their lives. Epimorphic development is used to describe arthropods which hatch with a set number of segments which does not increase with subsequent molts.
John A. Fornshell
doaj
Ecological Developmental Biology: Developmental Biology Meets the Real World
Developmental Biology, 2001 The production of phenotype is regulated by differential gene expression. However, the regulators of gene expression need not all reside within the embryo. Environmental factors, such as temperature, photoperiod, diet, population density, or the presence of predators, can produce specific phenotypes, presumably by altering gene-expression patterns. The
openaire +6 more sources