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Incorporating Genetics into Your Studies: A Guide for Social Scientists [PDF]
Frontiers in Psychiatry, 2011 There has been a surge of interest in recent years in incorporating genetic components into on-going longitudinal, developmental studies and related psychological studies. While this represents an exciting new direction in developmental science, much of
Danielle eDick +2 more
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Cryptic Genetic Variation in Evolutionary Developmental Genetics. [PDF]
Biology (Basel), 2016 Evolutionary developmental genetics has traditionally been conducted by two groups: Molecular evolutionists who emphasize divergence between species or higher taxa, and quantitative geneticists who study variation within species. Neither approach really comes to grips with the complexities of evolutionary transitions, particularly in light of the ...
Paaby AB, Gibson G.
europepmc +5 more sources
iScience, 2022 Summary: Sox17 gene expression is essential for both endothelial and endodermal cell differentiation. To better understand the genetic basis for the expression of multiple Sox17 mRNA forms, we identified and performed CRISPR/Cas9 mutagenesis of two ...
Linh T. Trinh +5 more
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EvoDevo: Past and Future of Continuum and Process Plant Morphology
Philosophies, 2020 Plants and animals are both important for studies in evolutionary developmental biology (EvoDevo). Plant morphology as a valuable discipline of EvoDevo is set for a paradigm shift.
Rolf Rutishauser
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iScience, 2020 Summary: Studies revealing molecular mechanisms underlying neural specification have majorly focused on the role played by different transcription factors, but less on non-nuclear components. Earlier, we reported mitochondrial superoxide dismutase (SOD2)
Smitha Bhaskar +5 more
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Advanced Genetics, 2021 ERBB3 is a pseudokinase domain‐containing member of the ERBB family of receptor tyrosine kinases (RTKs). Following ligand binding, ERBB receptors homo‐ or hetero‐dimerize, leading to a head‐to‐tail arrangement of the intracellular kinase domains, where ...
Kate Senger +19 more
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ROS Regulate Caspase-Dependent Cell Delamination without Apoptosis in the Drosophila Pupal Notum
iScience, 2020 Summary: Thorax fusion occurs in the midline of the Drosophila pupal notum and involves epithelial cell delamination requiring apoptotic signaling. By genetic screening, we found that NADPH oxidases (Nox and Duox) associated with superoxide anion (O˙-2 ...
Yuya Fujisawa +3 more
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Nature Communications, 2021 The vertebrate limb bud is a paradigm to uncover the fundamental mechanisms that govern embryogenesis and evolutionary diversification. Here the authors compare mouse and chicken limb bud development to study the impact of genome evolution on conserved ...
Shalu Jhanwar +5 more
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YAP regulates alveolar epithelial cell differentiation and AGER via NFIB/KLF5/NKX2-1
iScience, 2021 Summary: Ventilation is dependent upon pulmonary alveoli lined by two major epithelial cell types, alveolar type-1 (AT1) and 2 (AT2) cells. AT1 cells mediate gas exchange while AT2 cells synthesize and secrete pulmonary surfactants and serve as ...
Jason J. Gokey +6 more
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