Results 221 to 230 of about 16,668,975 (285)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Progenitor Timing Shapes NG2-Glia Fate and Oligodendrocyte Differentiation. [PDF]

Glia
Ojalvo-Sanz AC, Pernia-Solanilla C, López-Mascaraque L.   +2 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

When Development Falls out of Sync: A Developmental Timing Framework for Learning Disabilities. [PDF]

Brain Sci
Leisman G.
europepmc   +1 more source

Associations Between Early Screen Exposure and Neurocognitive Outcomes in Children Aged 2-5 Years: A Systematic Review. [PDF]

Healthcare (Basel)
Panayotova GG, Yakabova DN.
europepmc   +1 more source

Artificial intelligence interaction is not equivalent to social interaction: Rethinking artificial intelligence-mediated digital exposure in early childhood. [PDF]

Pediatr Investig
Çeri A, Yılmaz H.
europepmc   +1 more source