Results 51 to 60 of about 4,724,483 (271)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Orthopaedic SurgeryObjective Orthopedic implants may need to be removed for various reasons. There is little data on the appropriate handling of implants after their removal from patients.
Ali Engin Daştan +3 more
doaj +1 more source
SmartFSCV: An Artificial Intelligence Enabled Miniaturised FSCV Device Targeting Serotonin
IEEE Open Journal of Engineering in Medicine and BiologyGoal: Dynamically monitoring serotonin in real-time within target brain regions would significantly improve the diagnostic and therapeutic approaches to a variety of neurological and psychiatric disorders.
Dean M. Corva +7 more
doaj +1 more source
Preloaded latching device [PDF]
, 1992 A latching device is disclosed which is lever operated sequentially to actuate a set of collet fingers to provide a radial expansion and to actuate a force mechanism to provide a compressive gripping force for attaching first and second devices to one ...
Nagy, Kornel, Wesselski, Clarence J.
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Frontiers in Cardiovascular MedicineThis study aimed to investigate the long-term effects of different ASD closure methods on cardiovascular events in adults. A retrospective analysis was conducted using data obtained from the Korean National Health Insurance Service, focusing on patients ...
Jue Seong Lee +4 more
doaj +1 more source
Development of the device design and techique of color fastness testing of leather and finished goods to friction [PDF]
Vestnik of Vitebsk State Technological University, 2016 This article describes the design of the device for controlling the color fastness of leather to friction. The device is designed for inspection of color fastness on the finished shoes and leather products.
Anton Matveev +2 more
doaj
Contrasting Experimentally Device-Manipulated and Device-Free Smiles. [PDF]
, 2019 Researchers in psychology have long been interested in not only studying smiles, but in examining the downstream effects of experimentally manipulated smiles.
Cross, Marie P +2 more
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Fully integrated electrically driven optical frequency comb at communication wavelength
Nanophotonics, 2022 To meet the high demand of data transmission capacity, optical communications systems have been developed. In order to increase the channel numbers for larger communication bandwidth, multi-mode lasers and laser arrays can be used.
Li Nanxi +6 more
doaj +1 more source