Results 51 to 60 of about 1,289,043 (269)
MicromachinesThis work presents a novel and fully virtual flow for extracting the SPICE model of a power MOSFET, starting exclusively from TCAD simulations. Unlike traditional approaches that rely on experimental silicon data, our methodology enables designers to ...
Ammar Tariq +7 more
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STUDENTS’ COORDINATION SKILLS TESTING IN PHYSICAL EDUCATION: ICT APPLICATION
Інформаційні технології і засоби навчання, 2019 The informatisation of modern education necessitates the development of a new model of physical education, based on interdisciplinary integrative processes using ICT. This paper considers using ICT for testing coordination skills in physical education of
Victor M. Koryahin +3 more
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
HYBRID REED - SOLID-STATE DEVICES ARE A NEW GENERATION OF PROTECTIVE RELAYS
Elektrotehnìka ta Elektroenergetika, 2007 Author’s approach allows viewing the problem of re-equipment of relay protection in a new way. In the author’s opinion combination of reed switches with magnetic circuits and semiconductor elements opens new avenues in development of the promising ...
V. Gurevich
doaj
Éducation et SocialisationOutsourced teaching units (UEE) are “hybrids” schooling devices offering an adapted education to children with disabilities. These devices are part of the French government’s willingness to promote more inclusive education.
Clara Salesses
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Method of specific energy for determination mechanical characteristics of structural steel (rus) [PDF]
Инженерно-строительный журнал, 2011 The studies performed in present article are directed on improvement the practical methods of the existing steel structures examination. In particular, the new method for the determination of the mechanical properties of steel structure elements of the ...
Levanov A.V. +2 more
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source