Results 81 to 90 of about 2,228,667 (319)
Nanomaterials, 2020 Negatively charged microspheres (NCMs) represent a new therapeutic approach for wound healing since recent clinical trials have shown NCM efficacy in the recovery of hard-to-heal wounds that tend to stay in the inflammatory phase, unlocking the healing ...
Edorta Santos-Vizcaino +7 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
MicromachinesThis work presents a novel and fully virtual flow for extracting the SPICE model of a power MOSFET, starting exclusively from TCAD simulations. Unlike traditional approaches that rely on experimental silicon data, our methodology enables designers to ...
Ammar Tariq +7 more
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
HYBRID REED - SOLID-STATE DEVICES ARE A NEW GENERATION OF PROTECTIVE RELAYS
Elektrotehnìka ta Elektroenergetika, 2007 Author’s approach allows viewing the problem of re-equipment of relay protection in a new way. In the author’s opinion combination of reed switches with magnetic circuits and semiconductor elements opens new avenues in development of the promising ...
V. Gurevich
doaj
STUDENTS’ COORDINATION SKILLS TESTING IN PHYSICAL EDUCATION: ICT APPLICATION
Інформаційні технології і засоби навчання, 2019 The informatisation of modern education necessitates the development of a new model of physical education, based on interdisciplinary integrative processes using ICT. This paper considers using ICT for testing coordination skills in physical education of
Victor M. Koryahin +3 more
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Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Éducation et SocialisationOutsourced teaching units (UEE) are “hybrids” schooling devices offering an adapted education to children with disabilities. These devices are part of the French government’s willingness to promote more inclusive education.
Clara Salesses
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