Results 121 to 130 of about 333,056 (304)
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay +13 more
wiley +1 more source
A hybrid, iterative approach, to support the development of fit-for-purpose sensor-derived measures
Frontiers in Medical TechnologyDigital Health Technologies (DHTs) hold immense potential for transforming drug development. Although innovation in the DHT space has been rapid, the approval process for these technologies remains slow due to fragmented efforts from industry and ...
Belen R. Ballester +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma +16 more
wiley +1 more source
Reforming Medical Device Regulation
, 2016 Imagine a device that could help identify skin cancer by examining moles underneath a patient’s skin using light rather than incisions. The makers of just such a device, called MelaFind, found that it took more than two years for their product to gain ...
Melanson, Sarah
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RECENT ADVANCEMENT IN PEDIATRIC MEDICAL DEVICE DEVELOPMENT AND APPROVAL OF USFDA
The challenge in pediatric medical device development known as FDA barriers can be elaborated by the impacts of the characteristics and regulatory, ethical, and financial barriers in view that physiological and developmental aspects of children and ...
R KAMARAJ, V GURU PRASAD
core +1 more source
Key Information Influencing Patient Decision-Making About AI in Health Care: Survey Experiment Study
Journal of Medical Internet ResearchBackgroundArtificial intelligence (AI)–enabled devices are increasingly used in health care. However, there has been limited research on patients’ informational preferences, including which elements of AI device labeling enhance patient understanding ...
Xuan Zhu +7 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
, 2012 PhDVenous thromboembolism (VTE) is a significant preventable complication that causes morbidity and mortality not only in hospitalised patients, but also in healthy individuals.
Jawad, Huda
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground The Breakthrough Devices Program of the US Food and Drug Administration has accelerated the development and evaluation of medical devices for patients with heart failure.
Benjamin R. Saville +2 more
doaj +1 more source