Results 41 to 50 of about 315,340 (245)

Outcomes of Device Closure of Atrial Septal Defects

Children, 2020
Several devices have been designed and tried over the years to percutaneously close atrial septal defects (ASDs). Most of the devices were first experimented in animal models with subsequent clinical testing in human subjects.
P. Syamasundar Rao
doaj   +1 more source

Regulatory Device Approval for Stroke [PDF]

Stroke, 2007
Dr Pena et al provide a regulatory perspective on the Food and Drug Administration’s (FDA) device approval process.1 Reflecting the growing importance of the topic, this is the second such review and accompanying editorial comment to appear in Stroke ,2,3 the first being prompted by the FDA’s clearance of the MERCI retriever device.4 For those more ...
openaire   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Bridging the Gap in FDA Approval for Pediatric Neuromodulation Devices

Children
While neuromodulation devices for managing neurological conditions have significantly advanced, there remains a substantial gap in FDA-approved devices specifically designed for pediatric patients.
Ammar Shaikhouni, Cameron Brandon, Cory Criss   +2 more
doaj   +1 more source

Malfunctions of robotic system in surgery: role and responsibility of surgeon in legal point of view

Open Medicine, 2016
Robotic surgery (RS) technology has undergone rapid growth in the surgical field since its approval. In clinical practice, failure of robotic procedures mainly results from a surgeon’s inability or to a device malfunction.
Ferrarese Alessia, Pozzi Giada, Borghi Felice, Marano Alessandra, Delbon Paola, Amato Bruno, Santangelo Michele, Buccelli Claudio, Niola Massimo, Martino Valter, Capasso Emanuele   +10 more
doaj   +1 more source

Data on plug-based large-bore arteriotomy vascular closure device related access complications

Data in Brief, 2021
This article provides supplementary tables and figures to the research article: Frequency, Impact and Predictors of Access Complications with Plug-Based Large-Bore Arteriotomy Closure - A patient level meta-analysis [1].
Rutger-Jan Nuis, David Wood, Herbert Kroon, Maarten van Wiechen, Darra Bigelow, Chris Buller, Joost Daemen, Peter de Jaegere, Zvonimir Krajcer, John Webb, Nicolas Van Mieghem   +10 more
doaj   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Who Still Gets Ligated? Reasons for Persistence of Surgical Ligation of the Patent Ductus Arteriosus Following Availability of Transcatheter Device Occlusion for Premature Neonates

Journal of Cardiovascular Development and Disease
(1) Background: To identify reasons for the persistence of surgical ligation of the patent ductus arteriosus (PDA) in premature infants after the 2019 Food and Drug Administration (FDA) approval of transcatheter device closure; (2) Methods: We performed ...
Julia K. Hoffmann, Zahra Khazal, Wievineke Apers, Puneet Sharma, Constance G. Weismann, Kira Kaganov, Craig R. Wheeler, Michael Farias, Diego Porras, Philip Levy, Sarah U. Morton   +10 more
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source