Results 81 to 90 of about 25,823 (154)

Synthesis, characterization and evaluation of transfection efficiency of dexamethasone conjugated poly(propyleneimine) nanocarriers for gene delivery#

Pharmaceutical Biology, 2018
Context: Polypropylenimine (PPI), a cationic dendrimer with defined structure and positive surface charge, is a potent non-viral vector. Dexamethasone (Dexa) conveys to the nucleus through interaction with its intracellular receptor.
Bizhan Malaekeh-Nikouei, Mehdi Rezaee, Leila Gholami, Naghmeh Sanjar Mousavi, Reza Kazemi Oskuee   +4 more
doaj   +1 more source

Higher Bone Mineral Density in Obesity Masks Impaired Bone Remodeling and Disproportionate Musculoskeletal Adaptation in Young Women

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Women with obesity exhibited higher total and site‐specific BMD and greater lean mass than lean controls. However, reduced BMD‐to‐fat and lean‐to‐fat mass ratios, increased CTX1 and RANK‐L/OPG, and decreased P1NP and osteocalcin indicated impaired bone remodeling, suggesting that increased BMD masks altered bone turnover and compromised skeletal health.
Yasmin Silva Forte, Caio Andrade‐Santos, Camila Pantoja‐Marinho, Luísa González‐Joaquim, Aline Penna‐De‐Carvalho, Paulo Roberto Falcão Leal, Karynne Grutter Lopes, Luiz Guilherme Kraemer‐Aguiar, Christina Barja‐Fidalgo   +8 more
wiley   +1 more source

One-year metreleptin in Colombian sisters with congenital leptin deficiency

Adipocyte
We discovered two adult sisters in Colombia, lineally consanguineous, with severe obesity and undetectable serum leptin levels despite markedly elevated body fat.
Hernan Yupanqui-Lozno, Jancy Andrea Huertas-Quintero, Maria E. Yupanqui-Velazco, Rocío A. Salinas-Osornio, Carlos M. Restrepo, Adriana Gonzalez, Edna J. Nava-Gonzalez, Luis G. Celis-Regalado, Constanza Neri Morales, Victor M. Hernandez-Escalante, Julio Licinio, Hugo A. Laviada-Molina, Ernesto Rodriguez-Ayala, Carlos Arango, Raul A. Bastarrachea   +14 more
doaj   +1 more source

Abstract Supplement HIV Glasgow 8–11 November 2026, Glasgow, UK/Virtual

Journal of the International AIDS Society, Volume 29, Issue S6, November 2026.
wiley   +1 more source

The Role of DEXA Scanning in Secondary Fragility Fracture Prevention. [PDF]

J Orthop Physician Assist
Bartolovic G, Aperfine I, Cunningham E, Davison B, Fantoni B, Melott M, Pavlic E, Reed T, Sims M, Schmitt DM.   +9 more
europepmc   +1 more source

Entresto attenuates dexamethasone-induced metabolic dysfunction-associated steatotic features in rats: role of potential SGK1/FOXO3a regulatory pathway and cardio-metabolic axis. [PDF]

Front Pharmacol
Alreshidi MK, Saad KM, Zaghloul MS, Nader MA.   +3 more
europepmc   +1 more source

Tolerogenic Programming Promotes Human Cytomegalovirus Permissiveness in Dendritic Cells. [PDF]

Eur J Immunol
Rahmel-Stein K, Becker J, Lange B, Krajewski L, Eiz-Vesper B, Kalinke U.   +5 more
europepmc   +1 more source

Glucocorticoids Do Not Enhance BK Polyomavirus Replication in Human Renal Proximal Tubular Epithelial Cells In Vitro. [PDF]

Clin Transl Sci
Moest WT, Lalai RA, Prins J, de Vries APJ, Wessels E, van Kooten C, Feltkamp MCW, Rotmans JI.   +7 more
europepmc   +1 more source

CT Radiomics and Machine Learning for Three-Class Bone Density Classification: An Exploratory Comparison Across Lumbar Vertebral Levels. [PDF]

Tomography
Sozeri A, Batur H, Cay N.
europepmc   +1 more source

Diagnostic Accuracy of Body Mass Index, Bioelectrical Impedance Analysis, and Waist-to-Hip Ratio Against DEXA for Obesity in Saudi Arabia: A Cross-Sectional Study. [PDF]

Diagnostics (Basel)
Alotaibi HF, Alqahtani SA, Alfraidi A, Selan J, Altunusi F, Albatly A, AlMuhaidib S, Taib H, Arafat A, Alhazzani W.   +9 more
europepmc   +1 more source