Results 61 to 70 of about 25,823 (154)

Thrombocytopenia in Pregnancy: A 5‐Year Analysis of Characteristics and Practices From a Tertiary Academic Center

open access: yesInternational Journal of Laboratory Hematology, Volume 48, Issue 6, Page 1320-1329, December 2026.
ABSTRACT Background Moderate‐to‐severe thrombocytopenia (platelet count < 100 × 109/L) occurs in fewer than 1% of pregnancies, posing management challenges, particularly surrounding eligibility for neuraxial anesthesia. Although recent anesthesia guidelines recommend a platelet threshold ≥ 70 × 109/L, outcomes data applying these recommendations in ...
Mackenzie E. Lemieux, Ming Y. Lim
wiley   +1 more source

Inhibition of Mahkota Dewa (Phaleria macrocarpa) bioactive fraction on proliferation of human retinoblastoma tumor cells Y-79 through suppression of mRNA level of cyclin E

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2017
Objective: To prove the molecular mechanisms of Mahkota Dewa (Phaleria macrocarpa) in suppressing proliferation of human retinoblastoma cells through suppression of cell cycle's gene-regulators expression.
Nugroho Trilaksana   +3 more
doaj   +1 more source

The Association of Sarcopenic Obesity With Respiratory Function Outcomes in Adults: A Systematic Review and Meta‐Analysis

open access: yesObesity Reviews, Volume 27, Issue 12, December 2026.
ABSTRACT Sarcopenic obesity has been associated with various health conditions and mortality. Our objective was to systematically review and estimate the association between sarcopenic obesity and respiratory function outcomes. We searched EMBASE, MEDLINE, and Google Scholar for observational studies involving adults (≥ 18 years), defined sarcopenic ...
Tasneem Baabbad   +4 more
wiley   +1 more source

Associations Between Weight Status and Mental Well‐Being in Childhood and Adolescence: A Systematic Review of Longitudinal Studies

open access: yesObesity Reviews, Volume 27, Issue 12, December 2026.
ABSTRACT Introduction Obesity and poor mental well‐being in childhood and adolescence are growing public health concerns with potential implications for a broad range of life outcomes. Understanding the longitudinal and potentially bidirectional relationship between weight status and mental well‐being is crucial for developing effective interventions ...
Stine Schramm   +3 more
wiley   +1 more source

Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

open access: yesArthritis Care &Research, Volume 78, Issue 11, Page 1732-1740, November 2026.
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan   +10 more
wiley   +1 more source

Fecal Microbiota Transplantation: A Promising Therapeutic Strategy Targeting the Microbiota–Gut–Brain Axis in Anorexia Nervosa

open access: yesBrain and Behavior, Volume 16, Issue 11, November 2026.
Gut dysbiosis in anorexia nervosa may impair microbiota–gut–brain signaling through metabolic, immune, and vagal pathways. Fecal microbiota transplantation is being investigated as a potential strategy to restore host–microbiome balance, support a healthier microbial composition, and improve gastrointestinal function, appetite, and mood.
Shawn L. Kwok   +2 more
wiley   +1 more source

Pomegranate‐Derived Nanovesicles Exert Therapeutic Effects by Modulating Inflammatory Responses in a Murine Model of Chronic Dermatitis

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 11, November 2026.
ABSTRACT Extracellular vesicles are gaining attention in the pharmaceutical field due to their potential as therapeutic and delivery platforms. Among these, plant nanovesicles (PNVs) are particularly promising due to their reported biological activity.
Miquel Martínez‐Navarrete   +6 more
wiley   +1 more source

Evaluation of recombinant human erythropoietin as promoter of bone healing in cats with femoral fractures

open access: yesOpen Veterinary Journal
Background: The bone regeneration potential of erythropoietin (EPO) is not yet fully investigated, but some previous experimental studies demonstrated that its application activated the differentiation of osteoblasts and promoted bone formation.
Radina Vasileva, Tsvetan Chaprazov
doaj   +1 more source

Thrombus Degradation by Fibrinolytic Enzyme of Stenotrophomonas sp. Originated from Indonesian Soybean-Based Fermented Food on Wistar Rats

open access: yesAdvances in Pharmacological Sciences, 2016
Objective. To evaluate thrombus degrading effect of a fibrinolytic enzyme from food origin Stenotrophomonas sp. of Indonesia. Methods. Prior to animal study, the enzyme safety was tested using cell culture.
Florensia Nailufar   +2 more
doaj   +1 more source

Consensus Guidelines for Diagnosis and Management of Pyruvate Dehydrogenase Complex Deficiency

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Primary pyruvate dehydrogenase complex deficiency (PDCD) comprises a group of monogenic disorders caused by pathogenic variants in genes encoding subunits of, or regulatory components affecting, the pyruvate dehydrogenase complex. The clinical phenotype spans a broad continuum, ranging from early onset congenital lactic acidosis to infantile ...
Nandaki Keshavan   +23 more
wiley   +1 more source

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