Results 51 to 60 of about 25,823 (154)

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

RISK FACTORS FOR IMPAIRED BONE DENSITY IN MALE PATIENTS UNDERWENT HEMODIALYSIS DUE TO CHRONIC KIDNEY DISEASE

Journal Orthopaedi and Traumatology Surabaya, 2019
Background: Chronic kidney disease (CKD) is associated with impairment of mineral metabolism that, in turn, may result in the derangement of bone density, i.e. osteopenia or osteoporosis. Purpose: The objective of this study is to assess the impairment
Patritius Kelik Dwi Santo Ismoyo, Sugeng Yuwana   +1 more
doaj   +1 more source

Exercise during 14 days of head down tilt bedrest attenuates motor unit impairments in older humans

Experimental Physiology, EarlyView.
Abstract Head‐down tilt bedrest (HDBR) models the effects of mechanical unloading on neuromuscular function. The efficacy of exercise in preserving motor unit (MU) function in older adults during HDBR remains unclear. This study investigated the effects of 14‐day HDBR on MU properties in older adults and the protective role of exercise.
Philippe St‐Martin, Jean‐Christophe Lagacé, Mathil Ruel, Ahmed Ghachem, Guillaume Léonard, Eleonor Riesco, Mathew Piasecki, Jamie S. McPhee, Isabelle J. Dionne   +8 more
wiley   +1 more source

The acute effects of exercise intensity and inorganic nitrate supplementation on the Buckberg ratio in postmenopausal females

Experimental Physiology, EarlyView.
Abstract Menopause increases coronary heart disease risk, in part through reduced oestrogen‐mediated nitric oxide (NO) bioavailability. The Buckberg ratio, an index of myocardial oxygen supply–demand balance, in which higher values reflect more favourable myocardial perfusion, is lower in postmenopausal females (PMFs) than in age‐matched males.
Cassandra C. Derella, Austin C. Hogwood, Joaquin Ortiz de Zevallos, Nathan R. Weeldreyer, Kaitlin M. Love, Arthur Weltman, Jason D. Allen   +6 more
wiley   +1 more source

Comprehensive clinical review of osteoporosis in older adults: Diagnosis, management, and a UAE primary care perspective

Journal of Family Medicine and Primary Care
Osteoporosis is a progressive skeletal disorder characterized by reduced bone strength and an increased risk of fragility fractures, particularly among older adults. With rising life expectancy, osteoporosis has become a significant public health concern.
Affra Aftan Al Sheikh
doaj   +1 more source

From Prevention to Healthy Longevity: Evaluating the Multi‐Systemic Effects of Physical Activity and Lifestyle Behaviours in Women

Reproductive, Female and Child Health, Volume 5, Issue 4, December 2026.
ABSTRACT Purpose Despite spending more on healthcare than any other high‐income nation, the United States faces comparatively poor life expectancy outcomes, primarily due to non‐compliance with preventable and modifiable lifestyle behaviours. This review evaluates the multi‐systemic benefits of physical activity, exercise, diet, weight management and ...
Darah Dilmaghani, Mary Collins, Gloria A. Bachmann   +2 more
wiley   +1 more source

Dexamethasone alleviates tumor-associated brain damage and angiogenesis.

PLoS ONE, 2014
Children and adults with the most aggressive form of brain cancer, malignant gliomas or glioblastoma, often develop cerebral edema as a life-threatening complication.
Zheng Fan, Tina Sehm, Manfred Rauh, Michael Buchfelder, Ilker Y Eyupoglu, Nicolai E Savaskan   +5 more
doaj   +1 more source

World Health Organization Healthy Ageing model applied to adults with cerebral palsy: A systematic review of reported intrinsic capacity measures

Developmental Medicine &Child Neurology, Volume 68, Issue 12, Page 1657-1670, December 2026.
This systematic review reports on quantitative measures of intrinsic capacity domains of the WHO Healthy Ageing model for adults with CP. Reports from 102 studies showed reduced locomotor, vitality andn possibly cognitive intrinsic capacity reserves for adults aged 30–45 years.
Woroud Alzaher, N. Susan Stott, Paul Hofman, Amy Hogan, Sian A Williams   +4 more
wiley   +1 more source

Automated detection of bone splinters in DEXA phantoms using deep neural networks

Current Directions in Biomedical Engineering, 2019
Dual energy radiographic imaging is a method to provide material information and can be used to differentiate between various tissue types. Dual energy X-ray absorption (DEXA) can be applied for breast density, osteoporosis or bone fracture analysis.
Rüger Steffen, Firsching Markus, Lucic Julija, Ennen Alexander, Uhlmann Norman, Wittenberg Thomas   +5 more
doaj   +1 more source

Antenatal Corticosteroids in Gestational Diabetes: A Systematic Review of Glycemic Response and Management Strategies

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11006-11031, December 2026.
ABSTRACT Background Antenatal corticosteroids (ACS) promote foetal lung maturation in pregnancies at risk of preterm birth; however, in gestational diabetes mellitus (GDM), they can exacerbate maternal glycemia and contribute to adverse neonatal outcomes. Clinical guidelines offer limited direction on optimal treatment adjustment.
Alexandra Katz, Aidan Shulkin, Samantha Jacobson, Chella Price, Michael A. Tsoukas, Isabella Albanese, Agnieszka Majdan, Jill Pancer, Ariane Godbout, Kaberi Dasgupta, Anne‐Sophie Brazeau, Tricia Peters   +11 more
wiley   +1 more source