Results 121 to 130 of about 496,062 (355)
Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases
Advanced Healthcare Materials, EarlyView.This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.Min Ji Byun, Elizabeth S. Nakasone, Ha Eun Shin, Hyojin Lee, Jong‐Chan Park, Wonhwa Lee, Wooram Park, Chun Gwon Park, Juwon Park, Se‐Na Kim +9 morewiley +1 more sourceHigh-Dose Dexamethasone and Oxygen Support Strategies in Intensive Care Unit Patients With Severe COVID-19 Acute Hypoxemic Respiratory Failure: The COVIDICUS Randomized Clinical Trial.
JAMA Internal Medicine, 2022 L. Bouadma, A. Mekontso-Dessap, C. Burdet, H. Merdji, J. Poissy, C. Dupuis, C. Guitton, C. Schwebel, Y. Cohen, C. Bruel, Mehdi Marzouk, G. Geri, C. Cerf, B. Mégarbane, P. Garçon, Eric Kipnis, B. Visseaux, Naima Beldjoudi, S. Chevret, J. Timsit +19 moresemanticscholar +1 more sourceSelf‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma
Advanced Healthcare Materials, EarlyView.A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...Shannuo Li, Jiahui Li, Hasan Al Faruque, Paul Shami, Birgit Knoechel, Jens Lohr, Douglas Sborov, Jiyuan Yang, Jindřich Kopeček +8 morewiley +1 more sourceMesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery
Advanced Healthcare Materials, EarlyView.This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...Natividad Gómez‐Cerezo, Daniel Lozano, Antonio J. Salinas, María Vallet‐Regí +3 morewiley +1 more sourceEffects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans : a systematic review [PDF]
, 2009 BACKGROUND: Synthetic glucocorticoids are commonly used in reproductive medicine. Fetal organ systems are highly sensitive to changes in the intrauterine environment, including overexposure to glucocorticoids.1994 Effect of corticosteroids for fetal maturation on perinatal outcomes, Alkalay, Anderson, Andrews, Arlt, Arnold, Asa, Ashwood, Audus, Baker, Ballabh, Ballard, Ballard, Bamberger, Banks, Banks, Barbazanges, Battin, Baulieu, Benassayag, Benediktsson, Bertram, Bettendorf, Blanford, Blettner, Blumenfeld, Bolt, Bolt, Bradley, Bresson, Brosnan, Brown, Burlet, Buske-Kirschbaum, Buske-Kirschbaum, Buske-Kirschbaum, Buske-Kirschbaum, Buttgereit, Carroll, Cattarelli, Charmandari, Christopher Pryce, Chrousos, Cintra, Clifton, Cole, Condon, Crowley, Crowley, Cummings, Czock, Dalziel, Davis, Davis, Dawes, De Kloet, De Kloet, de Kloet, De Kloet, de Kloet, de Weerth, Dean, Dean, Diederich, Diego, Dobbing, Doyle, Dörr, Dörr, Dwan, Easterbrook, Ebrecht, Felszeghy, Fiad, Ford, French, French, Fries, Gatelais, Gayrard, Gennser, Giannakoulopoulos, Giannakoulopoulos, Gibbs, Gitau, Gitau, Glover, Goland, Grier, Grossmann, Gunther Meinlschmidt, Gutteling, Haley, Hanna, Hauser, Haussmann, Heckmann, Heim, Herman, Hingre, Holsboer, Högger, Ioannidis, Jahnukainen, Jaquier, Jeffray, Jobe, Jüni, Kairalla, Kajantie, Kajantie, Kalabis, Kalabis, Kamphuis, Kanitz, Kapoor, Kapoor, Karemaker, Kari, Karlsson, Karssen, Kauppila, Kavelaars, Keene, Kirschbaum, Klemcke, Kononen, Korte, Krauer, Lee, Lee, Lee, Levine, Levitt, Liggins, Liggins, Lindh, Lindsay, Little, Loebstein, MacArthur, Macnaughton, Manabe, Marinoni, Marion Tegethoff, Mark, Mark, Matthews, McAlister, Meadow, Mears, Meijer, Melby, Mesiano, Miller, Modi, Moss, Muneoka, Murphy, Murphy, Murphy, Murphy, National Institutes of Health Consensus Development Panel, Nelson, Nelson, Ng, Ng, Ng, Ng, Ng, Ng, Ng, Noguchi, Nomura, Noorlander, Nordenström, Nykänen, O'Regan, O'Shea, Oelkers, Ohrlander, Ohrlander, Oken, Olufemi, Osathanondh, Owen, Ozawa, Pacheco, Paddock, Parker Jr, Parker Jr, Patel, Peets, Pepe, Pepe, Petersen, Petersen, Petraglia, Petropoulos, Phillips, Pryce, Pryce, Reichardt, Reis, Rizvi, Roberts, Rocci Jr, Rosati, Samtani, Sandesh Kiran, Sapolsky, Sánchez, Schatz, Schwab, Schwab, Seckl, Seckl, Seckl, Serón-Ferré, Shulman, Sippell, Sloboda, Speirs, Speiser, Stein, Streeten, Stroup, Sucheston, Sun, Sybulski, Szabó, Taylor, Tenhola, Teramo, Terrone, Terrone, Thliveris, Trestman, Tsigos, Uhr, Uno, van der Heide-Jalving, Van Hoof, van Runnard Heimel, van Runnard Heimel, Veldhuis, Veldhuis, Vogl, Walters, Watterberg, Welberg, White, Whittaker, Wilson, Wittekind, Yates, Yeh, Yeh +257 morecore +2 more sourcesDexamethasone versus standard treatment for postoperative nausea and vomiting in gastrointestinal surgery: randomised controlled trial (DREAMS Trial)
British medical journal, 2017 Objectives To determine whether preoperative dexamethasone reduces postoperative vomiting in patients undergoing elective bowel surgery and whether it is associated with other measurable benefits during recovery from surgery, including quicker return to ...R. Ravikumar, D. Bartlett, D. Morton, L. Berkman, H. Bodenham-Chilton, J. Deeks, K. Handley, L. Magill, E. Hamilton, E. Hepburn, M. Hwang, Nazzia Mirza, A. Wilkey, M. Magill, A. Wilcockson, S. Mehta, A. Burtenshaw, W. Hawkins, M. Voysey, J. Blazeby, I. Smith, D. Stocken, S. Abbott, M. Hwang, A. Karim, D. P. Luke, D. Mcarthur, P. Mistry, J. Richardson, H. Youssef, K. Ravi, P. Goodfellow, R. Gupta, H. Joy, N. Eardley, C. Mcfaul, D. Vimalachandran, C. Harmston, P. Froggatt, P. Krishnan, S. Pathare, V. Shanmugam, Y. Yiannakou, A. Fawole, C. Macklin, J. McEnhill, H. Narula, T. Riad, A. Rose, J. Chambers, C. Ekere, M. Hough, J. Hull, H. Knight, M. Lamparelli, M. Lewis, M. Pulletz, N. Siddiqi, B. Stubbs, K. Subramanian, R. Swanton, S. Costigan, G. O'Connell, P. Patel, A. Ali, C. Ang, M. Chapman, U. Shariff, C. Thompson, A. Yates, D. Leinhardt, M. Simenacz, S. Harris, P. Loveless, Y. Mohsen, A. Myers, A. Prabhudesai, S. Vanagov, K. Aryal, R. Lal, D. Millican, I. Panagiotopopoulou, K. Shankar, M. Dube, J. Tansley, James O. Hill, S. Addison, R. Church, J. Nath, S. Valap, A. Dhrampal, J. Nortje, J. Payne, K. Sargen, C. Speakman, J. Deloughry, T. Elkington, R. Dennis, S. Ghosh, Janet E. Martin, M. Stoker, N. Åkerman, M. Basheer, N. Drury, C. Parchment-Smith, R. Sandhu, R. Srinivasa, S. Varma, S. Walwyn, N. Syed, J. Bromilow, P. Colling, H. Reschreiter, A. Senapati, F. Howse, L. Tzouliadis, S. Bach, A. Brookes, C. Cagigas, N. Dimitriou, S. Fallis, K. Futaba, A. Hill, A. Izbal, K. Leong, M. Manji, P. Milns, A. Murray, D. Nicol, T. Pinkney, S. Ramcharam, T. Royle, R. Scarpinata, C. Smart, S. Smart, N. Suggett, S. Sutherland, Y. Tam, A. Torrance, M. Wall, S. Vakis, M. Bassuini, J. Garner, S. Maz, M. Mottahedeh, M. Smith, M. Withers, R. Krishnamourthy, M. Paraoan, P. Thomas, N. Chesshire, S. Davies, S. Gold, I. Hamzah, N. Hurst, C. K. Khoo, S. Kiani, S. Liptrot, J. Lund, C. Millard, C. Morris, J. Reynolds, I. Selvaraj, A. Simpson, W. Speake, S. Tou, W. Chambers, A. Gee, A. Grice, D. Johnston, Q. Miller, J. Pittman, D. Price, R. Telford, E. Barrow, C. Coldwell, I. Crighton, T. Raymond, S. Richmond, M. Cheetham, G. Kulemeka, M. Carraretto, S. Huddart, J. Kirk-Bayley, D. Moor, M. Scott, M. Asif, R. Awan, R. Bethune, M. Chadwick, T. J. Cook, E. Courtney, S. Dalton, A. Lim, M. Williamson, J. Wood, R. Scott, G. Branagan, J. Bellin, D. Browning, V. Bulso, N. Carter, N. Cruikshank, K. Gill, N. Hulme, E. Leno, D. Newbould, V. Thumbe, K. Sankar, S. Sivasubramaniam, R. Wakhle, R. Walton, L. Zulueta, S. Ahmad, G. Kaur, D. Longbottom, M. Nnaji, A. Ramamoorthy, J. Thomas, I. Botteril, D. Miskovic, P. Sagar, S. Bhuptani, R. Kennedy, I. Jenkins, S. Littler, G. Arnold, G. Buchanan, A. Con, P. Dawson, S. Lawrie, J. Lowe, S. Malhotra, P. Paraskeva, S. Richards, V. Sidhu, P. Ziprin, D. Kruchek, A. Kuttler, K. Mohammad, T. Nasser, H. Rehman, K. Siddiqui, A. Siddiqui, Q. Sindhu, M. Soliman, M. Solkar, S. Thota, A. Renehan, C. Selvasekar, H. Melsom, A. Agarwal, D. Borowski, F. Brohi, D. Garg, T. Gill, V. Mahadevan, A. Sharma, M. Tabaqchali, T. Alce, A. Navapurkar, V. Page, T. Stambach, P. Capozzi, P. Coe, P. Conroy, S. Duff, T. Grey, O. Hill, J. Nicholson, D. Nolan, J. Pollard, A. Ramesh, M. Sabar, K. Telford, D. Davies, J. Wilson, D. Yates +277 moresemanticscholar +1 more source
