Results 121 to 130 of about 373,948 (350)

The protective effect of imatinib against pancreatic β-cell apoptosis induced by dexamethasone via increased GSTP1 expression and reduced oxidative stress

open access: yesScientific Reports
Glucocorticoids (GCs) are known to stimulate pancreatic beta (β)-cell apoptosis via several mechanisms, including oxidative stress. Our previous study suggested an increase in dexamethasone-induced pancreatic β-cell apoptosis via a reduction of ...
Namoiy Semprasert   +2 more
doaj   +1 more source

Dexamethasone Promotes the Risk of Cardiovascular Disease in High Fructose-exposed Wistar Rats

open access: yesIranian Journal of Toxicology, 2022
Background: Dyslipidemia constitutes a serious public health concern globally. It has been established that excessive fructose intake results in dyslipidemia; however, whether dexamethasone aggravates or alleviates fructose-induced dyslipidemia is ...
Adam Olaitan Abdulkareem   +2 more
doaj  

Response to Dexamethasone Suppression in Central Nervous System Disease [PDF]

open access: bronze, 1966
Dorothy T. Krieger   +2 more
openalex   +1 more source

Inhibition of RACK1‐Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome

open access: yesAdvanced Science, EarlyView.
Schematic diagram showing the potential mechanism of bigelovin on the activation of NLRP3 inflammasome Bigelovin may inhibit activated protein C kinase 1 (RACK1) by directly binding with cys168 of RACK1. Bigelovin thus prevents oligomerization of NLRP3 (NLRP3 active conformation) and subsequent assembly of NLRP3 inflammasome, blocking the activation of
Jian Cui   +17 more
wiley   +1 more source

Globule leukocytes and mast cells in the rat trachea: their number, distribution, and response to compound 48/80 and dexamethasone. [PDF]

open access: yes, 1988
Globule leukocytes in the epithelium of the rat trachea may be counterparts of mucosal mast cells that are located in the gastrointestinal tract. If they are indeed similar to mucosal mast cells, globule leukocytes would be expected to decrease in number
Calonico, LD   +3 more
core  

Comparative evaluation between two hybrid local anesthetics in lower third molar extraction: A retrospective study

open access: yesSRM Journal of Research in Dental Sciences
Background: Transalveolar extraction of the teeth may cause major serious complications, such as pain, swelling, and mouth opening. This study was conducted to find the most appropriate mixture of local anesthetics and glucocorticoids.
Sourav Kumar   +5 more
doaj   +1 more source

Microneedles at the Forefront of Next Generation Theranostics

open access: yesAdvanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang   +8 more
wiley   +1 more source

Preclinical Cushing's syndrome in adrenal incidentalomas [PDF]

open access: yes, 1992
Adrenal tumors are usually diagnosed by clinical symptoms of hormone excess. The increasing use of ultrasound and computed tomography results in the detection of a substantial number of incidentally discovered adrenal tumors.
Allolio, B.   +5 more
core  

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