Results 81 to 90 of about 515,791 (281)

Obesity programmed by prenatal dexamethasone and postnatal high-fat diet leads to distinct alterations in nutrition sensory signals and circadian-clock genes in visceral adipose tissue

Lipids in Health and Disease, 2019
Background Prenatal dexamethasone treatment has been shown to enhance the susceptibility of offspring to postnatal high-fat (HF) diet-induced programmed obesity.
Ching-Chou Tsai, Mao-Meng Tiao, Jiunn-Ming Sheen, Li-Tung Huang, You-Lin Tain, I-Chun Lin, Yu-Ju Lin, Yun-Ju Lai, Chih-Cheng Chen, Kow-Aung Chang, Hong-Ren Yu   +10 more
doaj   +1 more source

Dexamethasone and RU24858 induce survival and growth factor receptor bound protein 2, leukotriene B4 receptor 1 and annexin-1 expression in primary human neutrophils [PDF]

, 2012
Glucocorticoids are widely used anti-inflammatory medication in diseases like asthma and chronic obstructive pulmonary disease. Glucocorticoids can either activate (transactivation) or inhibit (transrepression) transcription. RU24858 was introduced as a
Adcock, I, Hasala, H, Janka-Junttila, M, Kankaanranta, H, Moilanen, E   +4 more
core   +3 more sources

Daratumumab plus bortezomib and dexamethasone versus bortezomib and dexamethasone in relapsed or refractory multiple myeloma: updated analysis of CASTOR

Haematologica, 2018
Daratumumab, a CD38 human monoclonal antibody, demonstrated significant clinical activity in combination with bortezomib and dexamethasone versus bortezomib and dexamethasone alone in the primary analysis of CASTOR, a phase 3 study in relapsed and/or ...
A. Spencer, S. Lentzsch, K. Weisel, H. Avet-Loiseau, T. Mark, I. Špička, T. Masszi, B. Lauri, M. Levin, A. Bosi, V. Hungria, M. Cavo, Je-Jung Lee, A. Nooka, H. Quach, Cindy H. Lee, W. Barreto, P. Corradini, C. Min, Emma C. Scott, A. Chanan-Khan, N. Horvath, M. Capra, M. Beksaç, R. Ovilla, J. Jo, H. Shin, P. Sonneveld, D. Soong, T. Casneuf, Christopher Chiu, H. Amin, M. Qi, P. Thiyagarajah, A. Sasser, J. Schecter, M. Mateos   +36 more
semanticscholar   +1 more source

Dexamethasone Treatment of Newborn Rats Decreases Cardiomyocyte Endowment in the Developing Heart through Epigenetic Modifications. [PDF]

PLoS ONE, 2015
The potential adverse effect of synthetic glucocorticoid, dexamethasone therapy on the developing heart remains unknown. The present study investigated the effects of dexamethasone on cardiomyocyte proliferation and binucleation in the developing heart ...
Maresha S Gay, Yong Li, Fuxia Xiong, Thant Lin, Lubo Zhang   +4 more
doaj   +1 more source

Dexamethasone Increases Cisplatin-Loaded Nanocarrier Delivery and Efficacy in Metastatic Breast Cancer by Normalizing the Tumor Microenvironment.

ACS Nano, 2019
Dexamethasone is a glucocorticoid steroid with anti-inflammatory properties used to treat many diseases, including cancer, in which it helps manage various side effects of chemo-, radio-, and immunotherapies.
John D. Martin, Myrofora Panagi, Chenyu Wang, Thahomina T Khan, Margaret R. Martin, C. Voutouri, K. Toh, P. Papageorgis, Fotios Mpekris, Christiana Polydorou, G. Ishii, Shinichirou Takahashi, N. Gotohda, Toshiyuki Suzuki, Matthew E Wilhelm, V. Melo, S. Quader, Jumpei Norimatsu, Ryan M Lanning, M. Kojima, M. D. Stuber, T. Stylianopoulos, K. Kataoka, H. Cabral   +23 more
semanticscholar   +1 more source

Glucocorticoid Receptor and Adipocyte Biology. [PDF]

, 2018
Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A, Lee, Rebecca A, Wang, Jen-Chywan   +2 more
core   +2 more sources

Daratumumab plus lenalidomide and dexamethasone versus lenalidomide and dexamethasone in relapsed or refractory multiple myeloma: updated analysis of POLLUX

Haematologica, 2018
In the POLLUX study, daratumumab plus lenalidomide/dexamethasone significantly reduced risk of progression/death versus lenalidomide/dexamethasone alone in relapsed/refractory multiple myeloma.
M. Dimopoulos, J. San-Miguel, A. Belch, D. White, L. Benboubker, G. Cook, M. Leiba, J. Morton, P. Ho, Kihyun Kim, N. Takezako, P. Moreau, J. Kaufman, H. Sutherland, M. Lalancette, H. Magen, S. Iida, Jin Seok Kim, H. Prince, T. Cochrane, A. Oriol, N. Bahlis, A. Chari, L. O’Rourke, K. Wu, J. Schecter, T. Casneuf, Christopher Chiu, D. Soong, A. Sasser, N. Khokhar, Hervé Avet-Loiseau, Z. Saad, Usmani   +33 more
semanticscholar   +1 more source

The Effects of Dexamethasone on Postoperative Complications After Surgical Removal of Impacted Lower Third Molar Teeth

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2014
The purpose of this study was to evaluate the effects of dexamethasone on postoperative complications after surgical removal of impacted lower third molar.
Haider Ali Rassul, Ahmad Fliah Hassan, Athil Adnan Raheem, Hajer Ibrahem   +3 more
doaj   +1 more source

Use and Outcomes of Dexamethasone in the Management of Malignant Small Bowel Obstruction

Annals of Surgery Open
Objective:. To describe rates of dexamethasone use in the nonoperative management of malignant small bowel obstruction (mSBO) and their outcomes. Background:. mSBO is common in patients with advanced abdominal-pelvic cancers.
Frank F. Yang, MD, Elina Serrano, MD, Kyle S. Bilodeau, MD, Michael Weykamp, MD, Caitlin J. Silvestri, MD, Ashleigh C. M. Bull, MD, Brenda Lin, MD, Sara L. Schaefer, MD, Colette Galet, PhD, Luis J. Garcia, MD, FACS, Baraka Gitonga, BS, David T. Kolodziej, BS, Samantha Esposito, BS, Molly Parker-Brigham, BS, Rohan Luhar, BS, Avinash Mamgain, MS, Kendrick C. Brown, BS, Summer Dewdney, MD, Thea P. Price, MD, FACS, Nicole Siparsky, MD, FACS, Sarah Knerr, PhD, Pauline K. Park, MD, FACS, Sabrina Sanchez, MD, FACS, Dionne A. Skeete, MD, FACS, Katherine N. Fischkoff, MD, FACS, David R. Flum, MD, FACS   +25 more
doaj   +1 more source

Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro [PDF]

, 2001
Angiogenesis, the formation of a new blood supply, is an essential step in tumorigenesis. Although vascular endothelial growth factor (VEGF) is known to be a very potent angiogenic factor in most solid tumors, little is known about its production and ...
Gloddek, Jutta, Hopfner, Ursula, Lohrer, Penny, Losa, Marco, Pagotto, Uberto, Renner, Ulrich, Stalla, Günter K., Uhl, Eberhard   +7 more
core   +1 more source