Results 81 to 90 of about 510,342 (390)
Long-term outcomes of dexamethasone 12 mg versus 6 mg in patients with COVID-19 and severe hypoxaemia [PDF]
, 2022 Anders Granholm +48 more
openalex +1 more source
Differentiation Treatment Applied to Lung Cancer Model Reduces Pathogenic Traits in Vitro
Advanced Biology, EarlyView.Non‐small cell lung cancer cells (A549) treated with a differentiation medium showed strong reduction in proliferation, migration, clonogenicity, spheroid formation and stemness markers, with enhanced adhesion properties and alveolar features, all pointing to a notably less aggressive phenotype in support of differentiation therapy as a promising ...
Alice Grossi +10 more
wiley +1 more source
Advanced Biology, EarlyView.In this study, Seaman et al. develop a co‐culture assay to examine interactions between prostate cancer cells and mineralized osteoblasts in a microfluidic platform. The authors collect conditioned media from static or flow‐stimulated osteocytes and demonstrate that mechanical loading of osteocytes regulates the growth of prostate cancer cells and ...
Kimberly Seaman +5 more
wiley +1 more source
Steroid induced osteonecrosis: An analysis of steroid dosing risk. [PDF]
, 2010 Osteonecrosis is a serious condition involving bone destruction that frequently requires surgical treatment to rebuild the joint. While there is an abundance of literature documenting corticosteroid related osteonecrosis, there is no consensus as to the ...
Chang, Christopher +4 more
core +1 more source
Lipids in Health and Disease, 2019 Background Prenatal dexamethasone treatment has been shown to enhance the susceptibility of offspring to postnatal high-fat (HF) diet-induced programmed obesity.
Ching-Chou Tsai +10 more
doaj +1 more source
Osteogenic Effects of Ion Released from Biodegradable Metallic Magnesium and Calcium Coating
Advanced Biology, EarlyView.This study explores how magnesium–calcium coatings on titanium promote osteogenesis by releasing ions and elevating pH during degradation. Using osteoblast‐like cells, the research demonstrates that both ion release and pH changes contribute to cell proliferation, differentiation, and mineralization, offering new insights into the design of bioactive ...
Risa Miyake +4 more
wiley +1 more source
Repression of DNA-binding dependent glucocorticoid receptor-mediated gene expression [PDF]
, 2009 The glucocorticoid receptor (GR) affects the transcription of genes involved in diverse processes, including energy metabolism and the immune response, through DNA-binding dependent and independent mechanisms.
Belitsky +26 more
core +2 more sources
Dexamethasone and long-term outcome of tuberculous meningitis in Vietnamese adults and adolescents. [PDF]
PLoS ONE, 2011 Dexamethasone has been shown to reduce mortality in patients with tuberculous meningitis but the long-term outcome of the disease is unknown.Vietnamese adults and adolescents with tuberculous meningitis recruited to a randomised, double-blind, placebo ...
M Estée Török +11 more
doaj +1 more source
Haematologica, 2018 Daratumumab, a CD38 human monoclonal antibody, demonstrated significant clinical activity in combination with bortezomib and dexamethasone versus bortezomib and dexamethasone alone in the primary analysis of CASTOR, a phase 3 study in relapsed and/or ...
A. Spencer +36 more
semanticscholar +1 more source