Results 101 to 110 of about 280,561 (284)

Effect of intravitreal dexamethasone implant on the contralateral eye in recalcitrant radiation maculopathy

Oman Journal of Ophthalmology, 2019
Radiation maculopathy, a subset of significant radiation retinopathy, is one of the most common causes of visual loss following localized, regional, or whole-brain radiotherapy.
Srishti Kamalmani Gulati, Gopal S Pillai, Natasha Radhakrishnan   +2 more
doaj   +1 more source

Comparative Analysis of Intravitreal Dexamethasone Implant (Ozurdex) and Brolucizumab Injection in the Treatment of Diabetic Macular Edema with Hyperreflective Intraretinal Dots: A Retrospective Study [PDF]

Somnath Chakraborty,1 Jay Umed Sheth2 1Department of Vitreoretinal Services, Retina Institute of Bengal, Siliguri, West Bengal, India; 2Department of Vitreoretinal Services, Shantilal Shanghvi Eye Institute, Mumbai, Maharashtra, IndiaCorrespondence ...
Sheth JU, Chakraborty S
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Puerarin‑Loaded pH‑Responsive ZIF‑90 Nanoparticles Ameliorate Osteoporosis via Enhancing H3K18 Lactylation and Suppressing Aberrant Osteoclast Activation

Advanced Science, EarlyView.
Schematic illustration of the mechanism by which ZIF‐90@PU alleviates osteoporosis via H3K18la‐mediated NFATc1 pathway suppression. ABSTRACT Osteoporosis is characterized by dysregulated osteoclast activity, leading to excessive bone resorption and structural damage.
Jiajia Lu, Yue Xi, Sheng Wang, Ye Chen, Jiajie Yang, Xiaojian Shi   +5 more
wiley   +1 more source

Switching to Aflibercept in Diabetic Macular Edema Not Responding to Ranibizumab and/or Intravitreal Dexamethasone Implant

Journal of Ophthalmology, 2017
Purpose. To assess short-term functional and anatomical outcomes of refractory diabetic macular edema (DME) following a switch from ranibizumab or dexamethasone to aflibercept. Methods.
Antoine Herbaut, Franck Fajnkuchen, Lise Qu-Knafo, Sylvia Nghiem-Buffet, Bahram Bodaghi, Audrey Giocanti-Auregan   +5 more
doaj   +1 more source

Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
An orally administered, drug‐free hyaluronic acid nanoassembly, uhNAs‐OA, accumulates in the inflamed colon and is preferentially internalized by M1‐like macrophages via HA‐CD44 interactions. uhNAs‐OA scavenges excess ROS, suppresses NF‐κB signaling and remodels the colonic immune landscape, resulting in robust therapeutic efficacy in acute, chronic ...
Jianqin Wan, Andi Ma, Yiqiong Zhang, Minghao Zhang, Yifeng Lin, Xiaoling Zhang, Hongjun Li, Weidong Han   +7 more
wiley   +1 more source

Rhegmatogenous Retinal Detachment with a High Risk of Proliferative Vitreoretinopathy Treated with Episcleral Surgery and an Intravitreal Dexamethasone 0.7-mg Implant

Case Reports in Ophthalmology, 2013
Purpose: To report a case of rhegmatogenous retinal detachment with a high risk of proliferative vitreoretinopathy (PVR) effectively treated with episcleral surgery and an intravitreal dexamethasone 0.7-mg implant.
Michele Reibaldi, Andrea Russo, Antonio Longo, Vincenza Bonfiglio, Maurizio G. Uva, Caterina Gagliano, Mario D. Toro, Teresio Avitabile   +7 more
doaj   +1 more source

Dexamethasone intravitreal implant (Ozurdex(A (R))) for pediatric uveitis

, 2015
The purpose of this study was to investigate the safety and effectiveness of an intravitreally injected dexamethasone-containing implant (Ozurdex(A (R))) in the treatment of uveitis in ...
Sella, Ruti, UMAR, Lewaa, Oray, Merih, Kramer, Michal, Friling, Ronit, Tugal-Tutkun, Ilknur   +5 more
core   +1 more source

Nascent Extracellular Matrix Converts Biomaterial Cues into Cell Fate Decisions

Advanced Science, EarlyView.
This study uncovers a tri‐directional interplay among cells, hydrogels, and their nascent extracellular matrix. Hydrogel norbornene modification alters CD44‐mediated cell–hydrogel interactions, which shape nascent matrix deposition, composition, and spatial organization.
Joshua Y. Liu, Ziqian Yang, Arina E. Velieva, Eleanor M. Plaster, Mingyue Fan, Donia W. Ahmed, Avinava Roy, Pamela Duran, Pamela Panovich, Alexandra S. Piotrowski‐Daspit, Carlos A. Aguilar, Megan L. Killian, Claudia Loebel   +12 more
wiley   +1 more source

An Injectable and Self‐Reinforced Piezoelectric Hydrogel for Irregular Bone Defects Regeneration: Dynamic Epigenetic Regulation Approach

Advanced Science, EarlyView.
An injectable and self‐reinforcing RSF‐based piezoelectric hydrogel conforms to irregular bone defects and progressively strengthens in situ, overcoming the trade‐off between injectability and mechanical stability. Mechanical loading generates bioelectrical cues that promote P300‐mediated H3K9 acetylation and upregulate PTH1R expression, thereby ...
Yu‐Kai Huang, Juan Li, Miao‐Miao Yang, Chao Jia, Quan‐Xin Gong, Guang‐Cheng Yuan, Dong Zhou, Wen‐Hui Shen, Zeng‐Gan Chen, Zhi‐Rui Dong, Jin‐Wang Huang, Jie Peng, Di‐Han Su, Ming‐Dong Zhao, Jian Dong, Li‐Bo Jiang   +15 more
wiley   +1 more source

Real-world assessment of intravitreal dexamethasone implant (0.7 mg) in patients with macular edema: the CHROME study

, 2015
Wai-Ching Lam,1 David A Albiani,2 Pradeepa Yoganathan,3 John Chanchiang Chen,4 Amin Kherani,5 David AL Maberley,6 Alejandro Oliver,7 Theodore Rabinovitch,3 Thomas G Sheidow,8 Eric Tourville,9 Leah A Wittenberg,10 Chris Sigouin,11 Darryl C Baptiste12 ...
Oliver A, Sigouin C, Yoganathan P, Lam WC, Chen JC, Maberley DAL, Rabinovitch T, Albiani DA, Sheidow TG, Kherani A, Wittenberg LA, Baptiste DC, Tourville E   +12 more
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