Results 171 to 180 of about 280,561 (284)

Redox‐Associated Renal and Male Reproductive Alterations Following Dexamethasone Exposure in Male Rats: Histopathological and Spermatological Evaluations

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Dexamethasone (DEX) is widely used in clinical practice, although it may also cause oxidative stress–related damage in different tissues, including the kidney and male reproductive system. This study investigated DEX‐induced renal and reproductive injury in rats and evaluated the modulatory effect of reduced glutathione on DEX‐associated redox
Caner Öztürk   +4 more
wiley   +1 more source

Delayed diagnosis of aluminum soda‐can cover impact in the upper esophagus of a toddler: A rare cause of chronic feeding difficulty and recurrent aspiration

open access: yesJPGN Reports, EarlyView.
Abstract Foreign body ingestion is a common occurrence in young children and may present with a wide range of nonspecific symptoms. Diagnosis can be challenging, particularly when the ingestion is unwitnessed and imaging studies are inconclusive. We present a case of a child with recurrent hospital admissions for respiratory symptoms that did not ...
Saleh Ibrahim Alsuqayh   +3 more
wiley   +1 more source

Intervention Outcomes for Meniere's Disease: An Umbrella Review

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objective To assess and summarize the outcomes of major pharmacologic, device‐based, and surgical interventions reported in systematic reviews and meta‐analyses for the treatment of Meniere's disease. Data Sources CINAHL, Cochrane, PubMed, Scopus.
Warren B. Chun   +7 more
wiley   +1 more source

Long-Term Intravitreal Dexamethasone Implant Monotherapy in Naïve Patients with Diabetic Macular Edema. [PDF]

open access: yesTurk J Ophthalmol
Karataş G   +7 more
europepmc   +1 more source

Evaluating the Local Response of a Novel Injectable Capsule for Drug Delivery in the Trachea

open access: yesThe Laryngoscope, EarlyView.
A novel PLGA polymer capsule was developed for localized pretracheal drug delivery and evaluated for short‐term local tissue safety in a rabbit model. Implant placement was confirmed by ultrasound and was well tolerated over 14 days, with preservation of airway patency, native tracheal architecture, and biomechanical properties.
Denzel Ryan D. Cruz   +7 more
wiley   +1 more source

Organoid Coculture Models for Cancer Research and Immunotherapy

open access: yesMed Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang   +9 more
wiley   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell   +6 more
wiley   +1 more source

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