ABSTRACT Background This study aimed to evaluate the predictive value of C1q (complement activation regulatory factor) for the occurrence of postoperative delirium (POD) following surgery for acute aortic dissection. Methods We prospectively included patients undergoing surgery for aortic dissection. Serum levels of C1q were measured preoperatively and
Jianing Wang +10 more
wiley +1 more source
The impact of using dexmedetomidine during surgery on the postoperative survival of cancer patients: a meta-analysis and systematic review of real-world studies. [PDF]
Zhu L, Liu Y, Mou W, Luo Z.
europepmc +1 more source
This work synthesizes recent insights into the pathological roles of cyclins and cyclin‐dependent kinases (CDKs) across human cancers, highlights state‐of‐the‐art innovative approaches (especially targeted degradation and redistribution of CDK/cyclin proteins) for cancer therapy, and outlines future directions for CDK/cyclin‐related biomedical research.
Suya Zheng +9 more
wiley +1 more source
Boosting Bupivacaine: The Role of Adjuvant Perineural Dexmedetomidine in Femoral Nerve Blocks. [PDF]
S A +5 more
europepmc +1 more source
Ferroptosis: Newly Emerged Regulator for Human Disease
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao +4 more
wiley +1 more source
Dexmedetomidine-Based Versus Opioid-Containing Periarticular Infiltration in High Tibial Osteotomy: A Retrospective Comparative Cohort Study. [PDF]
Usta HE, Ünlü R, Tekçe Y, Tekçe G.
europepmc +1 more source
ABSTRACT Background Children with congenital heart disease (CHD) frequently undergo cardiac magnetic resonance imaging (MRI) under anesthesia. Although these procedures lack surgical stimulus, patients remain physiologically vulnerable, and the incidence of perioperative cardiovascular instability in this setting is poorly defined.
Theodora Wingert +8 more
wiley +1 more source
Concomitant beta blocker therapy, intra-operative dexmedetomidine and postoperative cardiac events in older patients: a secondary analysis. [PDF]
Xue MX, Ma JH, Li CJ, Mu DL, Wang DX.
europepmc +1 more source
Effect of Intranasal Dexmedetomidine on the Night Before Surgery for Postoperative Delirium in Older Patients Undergoing Total Hip or Knee Arthroplasty: A Randomized Clinical Trial. [PDF]
Liu Y +12 more
europepmc +1 more source
Methods of Assessing Postoperative Pain in Infants (0–12 Months): A Scoping Review
ABSTRACT Infants undergoing surgery experience postoperative pain beyond acute short‐lasting procedural pain and have variable analgesic needs. Assessing pain in this nonverbal population presents challenges for clinicians and parents. Given the short‐ and long‐term effects of pain and its treatment, timely and accurate assessment of pain is vital. The
Jeewan Jyoti +5 more
wiley +1 more source

