Results 101 to 110 of about 4,394 (170)

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2723-2740, August 2026.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga, Stefano Agliardi, Riccardo Giossi, Alice Schianchi, Alessandra Romandini, Thomas Virdis, Silvia Nerini Molteni, Maria Luisa De Angelis, Stefania Paccagnini, Cecilia Gechtman, Alice Proto, Marco Fossati, Silvia Oliveri, Giulia Angela Pattarino, Elena Altieri, Agnese Graziosi, Arianna Pani, Romano Danesi, Stefano Martinelli, Costantino De Giacomo, Francesco Scaglione   +20 more
wiley   +1 more source

Unveiling the Microvasculature: The Index of Microcirculatory Resistance and Its Expanding Role in Cardiovascular Care

Catheterization and Cardiovascular Interventions, Volume 108, Issue 2, Page 287-300, August 1, 2026.
ABSTRACT Index of microcirculatory resistance (IMR) is a cutting‐edge, wire‐based tool that advances the capability assessment of coronary microvascular function. By utilizing distal coronary pressure and mean transit time under maximal hyperemia, IMR delivers consistent, reproducible insights into the microvasculature's dynamic health.
Joanna Sohn, Matthew A. Soderstrom, Ariana Ramirez, John‐Henry Dean, Raj Shah, Debanshu Roy, Kenneth Stone, Ariel Vinas, Bryan Ramsey, Charles Lin, Robert Chilton   +10 more
wiley   +1 more source

Sarcopenia Predicts Postoperative Cognitive Impairment and Poor Surgical Outcomes in Older Adults: A Prospective Cohort Study

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Sarcopenia is a progressive skeletal muscle disorder prevalent in older adults, yet its role as a risk factor for acute postoperative cognitive decline—an early manifestation within the spectrum of perioperative neurocognitive disorders (PND)—remains underexplored.
Xingming Tang, Yuncai Gu, Li Wang, Xiaochu Wu, Yipu Ren, Shudie Zhou, Yulong Cai, Xian Du, Xun Xia, Tianyao Zhang   +9 more
wiley   +1 more source

A Case of Rotator Cuff Tear Owing to External Electrical Cardioversion

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
External defibrillation during ablation complicated a massive rotator cuff tear.
Masahiro Watanabe, Shinichi Higuchi, Ayano Yuasa, Syun Hasegawa, Kinichi Kameyama   +4 more
wiley   +1 more source

Postoperative Nausea and Vomiting After Deep Sedation for Radiofrequency Catheter Ablation in Pediatric Patients

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
This retrospective study investigated the incidence of postoperative nausea and vomiting (PONV) in 70 pediatric radiofrequency catheter ablation procedures under deep sedation. PONV occurred in 17% of procedures, with a significantly higher incidence following left‐sided ablation. Importantly, the majority of PONV symptoms resolved spontaneously within
Yoshikatsu Takeda, Shuhei Fujita, Naoto Sakumura, Kazuyuki Ueno, Kengo Miyashita, Takeshi Futatani, Akio Chikata, Kazuo Usuda, Hidenori Iwasaki, Taichi Nakamura, Kunio Ohta, Taizo Wada   +11 more
wiley   +1 more source

Comparative Effectiveness of Antiarrhythmic Drugs on Early Atrial Tachyarrhythmias in the Blanking Period After Atrial Fibrillation Catheter Ablation

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
Bepridil, particularly in combination with aprindine, was highly effective for suppressing early recurrence of atrial tachyarrhythmia after AF ablation. Poor response to bepridil‐based therapy during the blanking period may identify patients at increased risk of late AF recurrence.
Asami Kashiwa, Yukio Hosaka, Yuka Hayashi, Komei Tanaka, Kazuyuki Ozaki, Masaomi Chinushi, Yoshifusa Aizawa, Kazuyoshi Takahashi   +7 more
wiley   +1 more source

Propofol‐induced hypertriglyceridemia in critically ill trauma patients requiring nutrition therapy: A descriptive cohort study

Journal of Parenteral and Enteral Nutrition, Volume 50, Issue 6, Page 794-804, August 2026.
Abstract Background This study aimed to assess the incidence and identify risk factors associated with the development of propofol‐induced hypertriglyceridemia in critically ill trauma patients who required nutrition therapy. Methods Adult patients (aged >17 years) admitted to the trauma intensive care unit who received propofol for >24 h and had a ...
Emma S. Lemke, Jonathon K. Walker, Julie E. Farrar, Saskya Byerly, Dina M. Filiberto, Roland N. Dickerson   +5 more
wiley   +1 more source

Utilizing Dynamic Liquid Crystal Elastomer Dressings to Enhance Early Dermal Wound Closure

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 4, August 2026.
This work introduces a new paradigm in skin wound closure by integrating smart materials with mechanomodulation, offering a non‐invasive and reusable alternative to traditional tension‐based closure methods. ABSTRACT Objective To evaluate whether a novel body temperature‐activated liquid crystal elastomer (LCE) bandage with contraction properties can ...
Clifford Jiajun He, Jeffrey D. Bernstein, Benjamin Bernard, Devyansh Agrawal, Gaoweiang Dong, Jennifer Lee, Shengqian Cai, David B. Hom   +7 more
wiley   +1 more source

Obstructive Sleep Apnea: Epidemiology, Pathophysiology, Complications, Diagnosis, Management, and Emerging Fibrosis‐Linked Remodeling

MedComm, Volume 7, Issue 8, August 2026.
Obstructive sleep apnea (OSA) is characterized by recurrent upper‐airway collapse, which generates key nocturnal stressors including intermittent hypoxia, sleep fragmentation, intrathoracic pressure stress, and sympathetic activation. These physiological disturbances converge on shared biological mechanisms, including oxidative stress, inflammation ...
Nhi Ho Thi Thuy, Thị Hằng Giang Phan, Ali Hussein Eid, Paola Maccioccu, Stefania Camboni, Gavino Casu, Anna Maria Posadino, Roberta Giordo, Gianfranco Pintus   +8 more
wiley   +1 more source

Selective Motor Stimulation of the Pudendal Nerve Using Multi‐Contact Cuff Electrodes: A Pre‐Clinical Study in Feline and Ovine Models

Neurourology and Urodynamics, Volume 45, Issue 6, Page 1210-1219, August 2026.
ABSTRACT Introduction Pudendal nerve stimulation is a promising therapy for urinary incontinence, however stimulation can evoke off‐target activity. We aimed to determine whether multi‐contact cuff electrodes can selectively recruit motor fibers of the pudendal nerve trunk in preclinical feline and ovine models.
Miguel Ortiz‐Lopez, Amador C. Lagunas, Hera Akmal, Tim M. Bruns   +3 more
wiley   +1 more source