Results 81 to 90 of about 51,358 (247)

Chinese Society of Pediatric Anesthesiology Guideline for Pediatric Sedation (2025)

Pediatric Anesthesia, EarlyView.
ABSTRACT Background With the increasing variety of pediatric diagnostic procedures, a growing number of children require sedation for diagnostic examinations. Appropriate sedation protocols guarantee the safety of children during sedation and improve its efficiency.
Xingrong Song, Dongxu Lei, Yu Cui, Zhen Du, Yingping Jia, Yue Jin, Hang Tian, Ying Xu, Lifang Yang, Jianmin Zhang, Jijian Zheng, Yunxia Zuo, Liang Zhong, John Zhong, Maryrose Osazuwa, Elizabeth Drum, Charles Dean Kurth, Yue Huang, Qinghua Huang, Heqi Liu, Wei Liu, Rui Ma, Dongpi Wang, Tingting Wang, Zixin Wang, Siwei Wei, Lei Yang, Rui Zhou, Liumei Chen, Weifeng Yu, Jun Li, Mazhong Zhang, Li Zhang, Shuangquan Qu, Shoudong Pan, Rong Wei, Liming Cheng, Yaolong Chen, Xueping Li, Zhenyu Tang   +39 more
wiley   +1 more source

Prophylactic Dexmedetomidine Reduces Junctional Ectopic Tachycardia and Facilitates Postoperative Recovery in Pediatric Cardiac Surgery: A Systematic Review and Meta‐Analysis of Prospective Trials

Pediatric Anesthesia, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of prophylactic dexmedetomidine in preventing Junctional Ectopic Tachycardia (JET) and its impact on postoperative recovery in pediatric congenital heart surgery, restricting analysis to prospective trials. Methods We systematically searched PubMed, Scopus, and CENTRAL through October 16, 2025, for
Michelle Singh, Arjun Anilkumar, Rohit Vondivillu Srinivasan, Jasim Abdul Jabbar, Naghul Malaichamy, Rethin Jayaraman   +5 more
wiley   +1 more source

Midazolam Efficacy Against Acute Hydrogen Sulfide-Induced Mortality and Neurotoxicity. [PDF]

, 2018
Hydrogen sulfide (H2S) is a colorless, highly neurotoxic gas. It is not only an occupational and environmental hazard but also of concern to the Department of Homeland Security for potential nefarious use. Acute high-dose H2S exposure causes death, while
Anantharam, Poojya, Imerman, Paula, Kim, Dong-Suk, Mahama, Belinda, Padhi, Piyush, Rumbeiha, Wilson K, Whitley, Elizabeth M   +6 more
core   +1 more source

Clinical effectiveness of a sedation protocol minimizing benzodiazepine infusions and favoring early dexmedetomidine: A before-after study [PDF]

, 2015
INTRODUCTION: Randomized controlled trials suggest clinical outcomes may be improved with dexmedetomidine as compared to benzodiazepines, however further study and validation is needed.
Boyle, Walter A, Drewry, Anne M, Fagley, Richard E, Field, R. Ryan, Kollef, Marin H, Lieu, Angela, Micek, Scott T, Olatunde, Joshua, Skrupky, Lee P, Varghese, Linda, Wessman, Brian   +10 more
core   +2 more sources

Analysis of serum biomarkers associated with pain in Spanish greyhounds undergoing ovariohysterectomy

Veterinary Record, EarlyView.
Background This study measured serum biomarkers at baseline and during an ovariohysterectomy in healthy female Spanish greyhounds, aiming to enhance the objectivity of current methods for assessing acute postoperative pain in dogs. Methods Blood samples from 20 Spanish greyhounds were collected before drug administration (T0‐baseline).
Rocio Navarrete‐Calvo, Jose Andrés Fernández‐Sarmiento, Juan Morgaz, Alba Galán‐Rodríguez, Rafael J. Gómez‐Villamandos, Pablo Parra, María del Mar Granados, Setefilla Quirós‐Carmona, Irene M. Rodríguez‐Gómez   +8 more
wiley   +1 more source

Highly variable pharmacokinetics of dexmedetomidine during intensive care: a case report

Journal of Medical Case Reports, 2010
Introduction Dexmedetomidine is a selective and potent alpha2-adrenoceptor agonist licensed for use in the sedation of patients initially ventilated in intensive care units at a maximum dose rate of 0.7 μg/kg/h administered for up to 24 hours.
Scheinin Mika, Kurvinen Juha-Pekka, Aantaa Riku, Kentala Erkki, Laitio Ruut, Iirola Timo, Olkkola Klaus T   +6 more
doaj   +1 more source

Intravenous paracetamol does not have significant opioid‐sparing effects when used as part of a multimodal analgesic protocol in dogs undergoing elective orthopaedic surgery

Veterinary Record, EarlyView.
Abstract Background Data evaluating paracetamol combined with NSAIDs in dogs are scarce. Results of clinical studies in dogs investigating intravenous paracetamol vary. Methods Dogs were randomised to either receive 10 mg/kg paracetamol intravenously after induction of anaesthesia and every 8 hours during hospitalisation (test) or not (control).
Robin Stallard, Julia Deutsch, Joanna Murrell   +2 more
wiley   +1 more source

41. The myocardial protective effect of dexmedetomidine in high risk patients undergoing aortic vascular surgery

Journal of the Saudi Heart Association, 2016
Dexmedetomidine provides perioperative cardiac protection in high risk patients assessment the effect of dexmedetomidine in high risk patients undergoing aortic vascular surgery. Arandomized study included 150 patients classified into two groups(n = 75).
R. Soliman
doaj   +1 more source

Designing the ideal perioperative pain management plan starts with multimodal analgesia. [PDF]

, 2018
Multimodal analgesia is defined as the use of more than one pharmacological class of analgesic medication targeting different receptors along the pain pathway with the goal of improving analgesia while reducing individual class-related side effects ...
Mariano, Edward R., Schwenk, Eric S.
core   +1 more source

Thalamocortical Oscillations in Sleep and Anaesthesia

, 2011
The last 20 years have seen a substantial advancement in the understanding of the molecular targets of general anaesthetics however the neural mechanisms involved in causing loss of consciousness remain poorly understood. Thalamocortical oscillations are
Gent, Thomas Clifford, Gent, Thomas Clifford   +1 more
core   +1 more source