Results 141 to 150 of about 51,358 (247)

Pharmacological treatment strategies to manage precipitated withdrawal following the administration of buprenorphine in opioid use disorder: A systematic review

Addiction, Volume 121, Issue 5, Page 1083-1099, May 2026.
Abstract Background and aims There has been limited evidence synthesis examining the treatment of buprenorphine precipitated opioid withdrawal (BPOW). We aimed to conduct the first systematic review to assess the clinical utility of any pharmacological intervention in the management of BPOW.
Emmert Roberts, Nicola Kalk, John Strang
wiley   +1 more source

Opioid‐free vs. opioid‐inclusive anaesthesia with or without regional anaesthesia for postoperative pain: a systematic review with network meta‐analysis of randomised controlled trials

Anaesthesia, Volume 81, Issue 5, Page 702-712, May 2026.
Summary Introduction Concerns about opioid‐related adverse effects have increased interest in opioid‐free anaesthesia, but the benefits compared with opioid‐inclusive techniques, especially in the presence of regional anaesthesia, remain uncertain. Methods We undertook a systematic review with a network meta‐analysis of randomised controlled trials ...
Clístenes C. de Carvalho, Kariem El‐Boghdadly, Idrys H. L. Guedes, Maria Vitória M. Dantas, Danusa P. B. Tomé, Isabella B. Ramos, Clarissa S. H. Gomes, Guilherme K. P. A. Alves, Arthur P. Bezerra, Jayme M. Santos Neto, Jaideep J. Pandit, Leandro G. Braz   +11 more
wiley   +1 more source

Pharmacological inhibition of hydroxysteroid 11‐beta dehydrogenase type 1 (11‐βHSD1) after myocardial infarction preserves cardiac function in a translational mini‐pig model

British Journal of Pharmacology, Volume 183, Issue 10, Page 2236-2255, May 2026.
Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi, Raimondo Ascione, Shazia Khan, Thomas Johnson, Eva Sammut, Vito Domenico Bruno, Daniel Baz Lopez, Carol‐Anne James, Joanna Simpson, Natalie Z. Homer, Michael Millar, Trisha Singh, Alex von Kreigsheim, Nick L. Mills, Brian R. Walker, Ruth Andrew, Scott P. Webster, Andrew Whittaker, Adrian Freeman, Gillian A. Gray   +19 more
wiley   +1 more source

Pregabalin contributes to increased recovery time from isoflurane anaesthesia for magnetic resonance imaging in horses

Equine Veterinary Journal, Volume 58, Issue 3, Page 736-746, May 2026.
Abstract Background Pregabalin reduces excitatory neurotransmitter release and is used for anxiolysis in humans, cats, and horses. The effects of pregabalin on equine recovery following isoflurane anaesthesia are unknown. Objectives To determine if pre‐anaesthetic oral pregabalin influences recovery time and/or quality from isoflurane anaesthesia in ...
Abigail Blanton, Kati G. Glass, Jeanette Bayer, Courtney Baetge, Ryota Watanabe, Sarah N. Sampson, Mauricio Lépiz, Kara Moreno, Keila K. Ida   +8 more
wiley   +1 more source

Effectiveness of dexmedetomidine versus fentanyl on postoperative pain and recovery after pediatric tonsillectomy: A retrospective cohort study. [PDF]

Saudi J Anaesth
Jallad M, AlAnazi B, Aloqbawi A, Albuthi M, Mahmoud AHM, Khan MI, AlDhuwaihy A, Alzuhayri F, Nagy M.   +8 more
europepmc   +1 more source

High‐Tech Augmentative and Alternative Communication in a Burn Patient With Voicelessness: A Case Study

Nursing in Critical Care, Volume 31, Issue 3, May 2026.
ABSTRACT Loss of speech due to mechanical ventilation is common among patients admitted to intensive care. This condition, often referred to as voicelessness, can generate negative emotions such as frustration and anger. Augmentative and Alternative Communication (AAC) techniques are useful for facilitating communication, but their use can be complex ...
Silvia Porcarelli, Monica Codara, Diletta Fabrizi, Michela Luciani, Davide Ausili   +4 more
wiley   +1 more source

Comparison of Three Different Doses of Dexmedetomidine for Attenuation of the Pressor Response to Laryngoscopy and Intubation by Assessment of Haemodynamic Parameters and Plasma Catecholamine Levels Under Bi-spectral Index Guided Anaesthesia - A Randomised Double Blind Controlled Study. [PDF]

Turk J Anaesthesiol Reanim
Gulabani M, Mohta M, Kumar N, Chawla D, Garg S, Tripathi S, Chauhan AS.   +6 more
europepmc   +1 more source

Early Sedation Intensity and Psychological Outcomes in Critically Ill Adults

Nursing in Critical Care, Volume 31, Issue 3, May 2026.
ABSTRACT Background Long‐term psychological impairment is a major concern for intensive care unit (ICU) survivors. Early deep sedation during mechanical ventilation has been associated with poor short‐term outcomes and mortality after ICU discharge; however, its relationship with psychological outcomes remains unclear.
Mikiko Iwatani, Michiko Morimoto
wiley   +1 more source

A Novel Standardized Dexmedetomidine Nasal Spray Formulation for Procedural Sedation During Venous Port Implantation: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. [PDF]

Drug Des Devel Ther
Tong J, Wei M, Ye Z, Gao H, Hong W, Cai P, Li W, Wang J, Zhou X, Liang C, Wang Z.   +10 more
europepmc   +1 more source

Technical Feasibility of the RHYTHMIA Mapping System in Pediatric Patients Weighing Less Than 20Kg

Pacing and Clinical Electrophysiology, Volume 49, Issue 5, Page 523-530, May 2026.
ABSTRACT Background Catheter ablation in pediatric patients remains technically challenging. The RHYTHMIA high‐density mapping system is increasingly used in pediatric electrophysiology; however, procedural experience in patients weighing less than 20 kg is limited.
Wataru Sasaki, Taisuke Nabeshima, Kouta Nagaoka, Hitoshi Mori, Daisuke Kudo, Naomichi Tanaka, Tsukasa Naganuma, Masataka Narita, Kazuhisa Matsumoto, Yoshifumi Ikeda, Naokata Sumitomo, Kazuo Matsumoto, Ritsushi Kato   +12 more
wiley   +1 more source