ABSTRACT Perioperative rhabdomyolysis can occur after prolonged laparoscopic nephrectomy, particularly in obese patients positioned in the lateral decubitus position. In high‐risk patients undergoing prolonged surgery, early postoperative creatine kinase measurement is essential for timely diagnosis.
Madeline Dow +2 more
wiley +1 more source
An Exploratory Analysis of Potential Core Targets and Signaling Pathways Linking Dexmedetomidine to Diabetes Insipidus: Integration of FAERS Pharmacovigilance Data, Network Toxicology and Clinical Transcriptomics. [PDF]
Ming S +6 more
europepmc +1 more source
ABSTRACT A 62‐year‐old man presented comatose with pH 6.88 and no ingestion history. A point‐of‐care lactate above 31 mmol/L with a laboratory lactate of 0.8 mmol/L revealed a lactate gap, diagnosing ethylene glycol poisoning despite a near‐normal osmolar gap. High‐dose continuous renal replacement therapy corrected the acidosis; he survived.
Jacob Athans, Prashant Maan
wiley +1 more source
Traumatic brain injury (TBI) induces acute, sex‐specific activation of endoplasmic reticulum (ER) stress, inflammatory signaling, and ferroptotic mechanisms within brain microvascular endothelial cells (BMECs). Administration of dexmedetomidine (DEX) produces both sex‐dependent and sex‐independent modulatory effects on BMECs, prominently suppressing ...
Yara Mashal +6 more
wiley +1 more source
Anesthesia-Informed Approaches to Insomnia: Shared Neural Circuits, Biomimetic Sleep, and Emerging Interventional Strategies. [PDF]
Wu Y, Yu X, Sun H, Huang F, Wang J.
europepmc +1 more source
Hemodynamic Effects of Interfacility Dexmedetomidine Infusions During Transport of Patients with Alpha-2-adrenergic Agonist Withdrawal. [PDF]
Goldstein S +4 more
europepmc +1 more source
Abstract Background North Lantau Hospital (NLTH) is a community hospital. The Emergency Medicine Advanced Care Unit (EMACU) was established to provide local critical care to unstable patients. Objective To evaluate the impact of EMACU on medical admissions and to compare outcomes between severe acute exacerbation of chronic obstructive pulmonary ...
Hui Pong Lai +10 more
wiley +1 more source
Effects of Dexmedetomidine or Sufentanil Plus Low-Dose Ropivacaine for Epidural Labor Analgesia on Maternal Intrapartum Temperature Changes and Delivery Outcomes. [PDF]
Deng Z, Yao R, Che Y, Wu X.
europepmc +1 more source
ABSTRACT Background and Aims In anesthesia and analgesia, opioids alone or in combination with local anesthetics (bupivacaine, lidocaine, and ropivacaine) have been investigated to prolong peripheral nerve blocks. Ultra‐low‐dose naloxone administration in local anesthetic solutions could lengthen sensory and motor blocks through enhanced opioid effects
Mohammadjavad Mehrabanian +7 more
wiley +1 more source
Dexmedetomidine and Postoperative Gastrointestinal Recovery: A Critical Narrative Review of Direct Enteric and Opioid-Sparing Pathways. [PDF]
Pan Y, Ding J, Feng J, Pan Z.
europepmc +1 more source

