Results 181 to 190 of about 28,483 (230)
Sedative Effects of Dexmedetomidine and Ketamine or Dexmedetomidine and Midazolam on Tear Production, Ocular Perfusion Pressure and Pupil Diameter in Rabbits. [PDF]
Mohammadzadeh M +2 more
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Dexmedetomidine for the prevention of postoperative atrial fibrillation: A systematic review and meta-analysis. [PDF]
Chen YJ, Xu SS, Shen QH, Yu DH.
europepmc +1 more source
Hemodynamic Effects of Anesthetics, Sedatives, and Analgesics in the CICU: Clinical Decision Guidance. [PDF]
Safiullah ZN +8 more
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On the Robustness of Preoperative Intranasal Dexmedetomidine for Postoperative Delirium Prevention: Methodological Considerations [Letter]. [PDF]
Gai H, Bao M, Chen B.
europepmc +1 more source
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BMJ Supportive & Palliative Care, 2020
Dexmedetomidine is a selective α2-adrenoreceptor agonist with a broad range of effects, including easily controllable sedation, analgesia and anxiolysis. Because of these favorable features, it has replaced traditional sedatives, such as benzodiazepines, and is becoming the first-line sedative for the patients in intensive care units.
Akiko Mano +8 more
openaire +2 more sources
Dexmedetomidine is a selective α2-adrenoreceptor agonist with a broad range of effects, including easily controllable sedation, analgesia and anxiolysis. Because of these favorable features, it has replaced traditional sedatives, such as benzodiazepines, and is becoming the first-line sedative for the patients in intensive care units.
Akiko Mano +8 more
openaire +2 more sources
Der Anaesthesist, 2013
Dexmedetomidine is a highly selective α2-receptor agonist with sedative, analgetic and anxiolytic effects. It is chemically related to clonidine and has been an authorized drug in Europe since September 2011. Dexmedetomidine enables a level of sedation in which mechanically ventilated patients may be woken by verbal stimulation (Richmond agitation ...
G, Gerresheim, U, Schwemmer
openaire +2 more sources
Dexmedetomidine is a highly selective α2-receptor agonist with sedative, analgetic and anxiolytic effects. It is chemically related to clonidine and has been an authorized drug in Europe since September 2011. Dexmedetomidine enables a level of sedation in which mechanically ventilated patients may be woken by verbal stimulation (Richmond agitation ...
G, Gerresheim, U, Schwemmer
openaire +2 more sources
Drugs, 2000
Dexmedetomidine is a potent alpha2-adrenoceptor agonist with 8 times higher affinity for the alpha2-adrenoceptor than clonidine. Dexmedetomidine has shown sedative, analgesic and anxiolytic effects after intravenous administration to healthy volunteers or postsurgical patients in the intensive care unit.
N, Bhana, K L, Goa, K J, McClellan
openaire +2 more sources
Dexmedetomidine is a potent alpha2-adrenoceptor agonist with 8 times higher affinity for the alpha2-adrenoceptor than clonidine. Dexmedetomidine has shown sedative, analgesic and anxiolytic effects after intravenous administration to healthy volunteers or postsurgical patients in the intensive care unit.
N, Bhana, K L, Goa, K J, McClellan
openaire +2 more sources
Current Opinion in Critical Care, 2001
Effective use of sedative-hypnotic and analgesic agents is an integral part of providing patient comfort and safety. Of the numerous drugs administered, benzodiazepines, propofol, and narcotics are the most popular. Even these proven, time-tested sedative-hypnotics and analgesics are not perfect, however, and modern intensive care demands a more ideal ...
D B, Coursin +2 more
openaire +2 more sources
Effective use of sedative-hypnotic and analgesic agents is an integral part of providing patient comfort and safety. Of the numerous drugs administered, benzodiazepines, propofol, and narcotics are the most popular. Even these proven, time-tested sedative-hypnotics and analgesics are not perfect, however, and modern intensive care demands a more ideal ...
D B, Coursin +2 more
openaire +2 more sources
Journal of Veterinary Pharmacology and Therapeutics, 2012
The purpose of this study was to assess the clinical effects of dexmedetomidine, both alone and combined with pethidine or butorphanol, in cats. A prospective randomized blind study was performed. Thirty cats were randomly assigned to three groups of 10 animals: D: dexmedetomidine (20 μg/kg IM); DP: dexmedetomidine (10 μg/kg IM) and pethidine (2.5 mg ...
L, Nagore +5 more
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The purpose of this study was to assess the clinical effects of dexmedetomidine, both alone and combined with pethidine or butorphanol, in cats. A prospective randomized blind study was performed. Thirty cats were randomly assigned to three groups of 10 animals: D: dexmedetomidine (20 μg/kg IM); DP: dexmedetomidine (10 μg/kg IM) and pethidine (2.5 mg ...
L, Nagore +5 more
openaire +2 more sources
Dexmedetomidine in anaesthesia
Current Opinion in Anaesthesiology, 2005The development of dexmedetomidine, a potent and highly selective alpha2-adrenoceptor agonist, has created new interest in the use of alpha2-adrenoceptor agonists, and has led to its evaluation in various yet non-approved perioperative settings. The current review focuses on the usefulness of dexmedetomidine in anaesthesia practice.Recently acquired ...
Andrea, Paris, Peter H, Tonner
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