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Safety and Efficacy of Dexmedetomidine as an Adjuvant in Epidural Anesthesia for Labor Analgesia: A Narrative Review. [PDF]
Med Sci (Basel)Feeney JM +7 more
europepmc +1 more source
Dexmedetomidine vs. midazolam-fentanyl for intraoperative analgesia and sedation: a systematic review and meta analysis. [PDF]
Front Pain Res (Lausanne)Hashim HT +14 more
europepmc +1 more source
A randomized prospective study comparing intracuff dexmedetomidine and alkalinized lidocaine for the prevention of postoperative sore throat, hoarseness, and cough in prolonged prone-position spine surgery. [PDF]
Saudi J AnaesthDaabiss M +4 more
europepmc +1 more source
Reactions WeeklyRecent research highlights the potential of dexmedetomidine, an α2-adrenoreceptor agonist, as a preventive treatment for postpartum depression (PPD). Originally studied in anesthetic settings, dexmedetomidine has shown antidepressant effects, reducing ...
Peitl, Vjekoslav, Vlahović, Darko
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BMJ Supportive & Palliative Care, 2020
Dexmedetomidine is a selective α2-adrenoreceptor agonist with a broad range of effects, including easily controllable sedation, analgesia and anxiolysis. Because of these favorable features, it has replaced traditional sedatives, such as benzodiazepines, and is becoming the first-line sedative for the patients in intensive care units.
Akiko Mano +8 more
openaire +2 more sources
Dexmedetomidine is a selective α2-adrenoreceptor agonist with a broad range of effects, including easily controllable sedation, analgesia and anxiolysis. Because of these favorable features, it has replaced traditional sedatives, such as benzodiazepines, and is becoming the first-line sedative for the patients in intensive care units.
Akiko Mano +8 more
openaire +2 more sources
Current Opinion in Critical Care, 2001
Effective use of sedative-hypnotic and analgesic agents is an integral part of providing patient comfort and safety. Of the numerous drugs administered, benzodiazepines, propofol, and narcotics are the most popular. Even these proven, time-tested sedative-hypnotics and analgesics are not perfect, however, and modern intensive care demands a more ideal ...
D B, Coursin +2 more
openaire +2 more sources
Effective use of sedative-hypnotic and analgesic agents is an integral part of providing patient comfort and safety. Of the numerous drugs administered, benzodiazepines, propofol, and narcotics are the most popular. Even these proven, time-tested sedative-hypnotics and analgesics are not perfect, however, and modern intensive care demands a more ideal ...
D B, Coursin +2 more
openaire +2 more sources
Drugs, 2000
Dexmedetomidine is a potent alpha2-adrenoceptor agonist with 8 times higher affinity for the alpha2-adrenoceptor than clonidine. Dexmedetomidine has shown sedative, analgesic and anxiolytic effects after intravenous administration to healthy volunteers or postsurgical patients in the intensive care unit.
N, Bhana, K L, Goa, K J, McClellan
openaire +2 more sources
Dexmedetomidine is a potent alpha2-adrenoceptor agonist with 8 times higher affinity for the alpha2-adrenoceptor than clonidine. Dexmedetomidine has shown sedative, analgesic and anxiolytic effects after intravenous administration to healthy volunteers or postsurgical patients in the intensive care unit.
N, Bhana, K L, Goa, K J, McClellan
openaire +2 more sources
Der Anaesthesist, 2013
Dexmedetomidine is a highly selective α2-receptor agonist with sedative, analgetic and anxiolytic effects. It is chemically related to clonidine and has been an authorized drug in Europe since September 2011. Dexmedetomidine enables a level of sedation in which mechanically ventilated patients may be woken by verbal stimulation (Richmond agitation ...
G, Gerresheim, U, Schwemmer
openaire +2 more sources
Dexmedetomidine is a highly selective α2-receptor agonist with sedative, analgetic and anxiolytic effects. It is chemically related to clonidine and has been an authorized drug in Europe since September 2011. Dexmedetomidine enables a level of sedation in which mechanically ventilated patients may be woken by verbal stimulation (Richmond agitation ...
G, Gerresheim, U, Schwemmer
openaire +2 more sources
Journal of Veterinary Pharmacology and Therapeutics, 2012
The purpose of this study was to assess the clinical effects of dexmedetomidine, both alone and combined with pethidine or butorphanol, in cats. A prospective randomized blind study was performed. Thirty cats were randomly assigned to three groups of 10 animals: D: dexmedetomidine (20 μg/kg IM); DP: dexmedetomidine (10 μg/kg IM) and pethidine (2.5 mg ...
L, Nagore +5 more
openaire +2 more sources
The purpose of this study was to assess the clinical effects of dexmedetomidine, both alone and combined with pethidine or butorphanol, in cats. A prospective randomized blind study was performed. Thirty cats were randomly assigned to three groups of 10 animals: D: dexmedetomidine (20 μg/kg IM); DP: dexmedetomidine (10 μg/kg IM) and pethidine (2.5 mg ...
L, Nagore +5 more
openaire +2 more sources