Results 261 to 270 of about 68,717 (285)
Some of the next articles are maybe not open access.
Current Opinion in Critical Care, 2001
Effective use of sedative-hypnotic and analgesic agents is an integral part of providing patient comfort and safety. Of the numerous drugs administered, benzodiazepines, propofol, and narcotics are the most popular. Even these proven, time-tested sedative-hypnotics and analgesics are not perfect, however, and modern intensive care demands a more ideal ...
D B, Coursin +2 more
openaire +2 more sources
Effective use of sedative-hypnotic and analgesic agents is an integral part of providing patient comfort and safety. Of the numerous drugs administered, benzodiazepines, propofol, and narcotics are the most popular. Even these proven, time-tested sedative-hypnotics and analgesics are not perfect, however, and modern intensive care demands a more ideal ...
D B, Coursin +2 more
openaire +2 more sources
Drugs, 2000
Dexmedetomidine is a potent alpha2-adrenoceptor agonist with 8 times higher affinity for the alpha2-adrenoceptor than clonidine. Dexmedetomidine has shown sedative, analgesic and anxiolytic effects after intravenous administration to healthy volunteers or postsurgical patients in the intensive care unit.
N, Bhana, K L, Goa, K J, McClellan
openaire +2 more sources
Dexmedetomidine is a potent alpha2-adrenoceptor agonist with 8 times higher affinity for the alpha2-adrenoceptor than clonidine. Dexmedetomidine has shown sedative, analgesic and anxiolytic effects after intravenous administration to healthy volunteers or postsurgical patients in the intensive care unit.
N, Bhana, K L, Goa, K J, McClellan
openaire +2 more sources
Journal of Veterinary Pharmacology and Therapeutics, 2012
The purpose of this study was to assess the clinical effects of dexmedetomidine, both alone and combined with pethidine or butorphanol, in cats. A prospective randomized blind study was performed. Thirty cats were randomly assigned to three groups of 10 animals: D: dexmedetomidine (20 μg/kg IM); DP: dexmedetomidine (10 μg/kg IM) and pethidine (2.5 mg ...
L, Nagore +5 more
openaire +2 more sources
The purpose of this study was to assess the clinical effects of dexmedetomidine, both alone and combined with pethidine or butorphanol, in cats. A prospective randomized blind study was performed. Thirty cats were randomly assigned to three groups of 10 animals: D: dexmedetomidine (20 μg/kg IM); DP: dexmedetomidine (10 μg/kg IM) and pethidine (2.5 mg ...
L, Nagore +5 more
openaire +2 more sources
Dexmedetomidine in anaesthesia
Current Opinion in Anaesthesiology, 2005The development of dexmedetomidine, a potent and highly selective alpha2-adrenoceptor agonist, has created new interest in the use of alpha2-adrenoceptor agonists, and has led to its evaluation in various yet non-approved perioperative settings. The current review focuses on the usefulness of dexmedetomidine in anaesthesia practice.Recently acquired ...
Andrea, Paris, Peter H, Tonner
openaire +2 more sources
Journal of the American Veterinary Medical Association, 2003
Abstract Objective—To determine sedative and cardiorespiratory effects of dexmedetomidine alone and in combination with butorphanol or ketamine in cats. Design—Randomized crossover study. Animals—6 healthy adult cats. Procedures—Cats were given dexmedetomidine alone (10 μg/kg [4.5 mg/lb], IM), a combination of ...
André L, Selmi +4 more
openaire +2 more sources
Abstract Objective—To determine sedative and cardiorespiratory effects of dexmedetomidine alone and in combination with butorphanol or ketamine in cats. Design—Randomized crossover study. Animals—6 healthy adult cats. Procedures—Cats were given dexmedetomidine alone (10 μg/kg [4.5 mg/lb], IM), a combination of ...
André L, Selmi +4 more
openaire +2 more sources
Drugs of Today, 1999
Pharmacological manipulation of the sympathetic tone has led to the synthesis of novel compounds to control stress-induced hemodynamic disorders. The use of alpha(2)-adrenoceptor agonists is particularly interesting in this regard, since these agents decrease sympathetic activity by reducing norepinephrine release from nerve terminals.
openaire +2 more sources
Pharmacological manipulation of the sympathetic tone has led to the synthesis of novel compounds to control stress-induced hemodynamic disorders. The use of alpha(2)-adrenoceptor agonists is particularly interesting in this regard, since these agents decrease sympathetic activity by reducing norepinephrine release from nerve terminals.
openaire +2 more sources
ICU Director, 2013
Objective. To provide a general descriptive account and review of the literature regarding the use of dexmedetomidine for sedation during fiberoptic bronchscopic (FOB) intubation. Data Source. A computerized bibliographic search of the literature regarding dexmedetomidine for FOB intubation. Main Results.
Joseph D. Tobias +2 more
openaire +2 more sources
Objective. To provide a general descriptive account and review of the literature regarding the use of dexmedetomidine for sedation during fiberoptic bronchscopic (FOB) intubation. Data Source. A computerized bibliographic search of the literature regarding dexmedetomidine for FOB intubation. Main Results.
Joseph D. Tobias +2 more
openaire +2 more sources