Results 1 to 10 of about 30,299 (192)

Effect of Bupivacaine Liposome Injectable Suspension on Sensory Blockade and Analgesia for Dupuytren Contracture Release

Journal of Hand Surgery Global Online, 2019
Purpose: To study the efficacy of bupivacaine liposome injectable suspension in prolonging sensory blocks of the median and ulnar nerves for subjects with Dupuytren contracture release by collagenase injection.
Catherine F. Vandepitte, MD, PhD, Sam Van Boxstael, MD, Joris F. Duerinckx, MD, Ine Leunen, MD, Maxine M. Kuroda, PhD, MPH, Dieter Mesotten, MD, PhD, Marc Van De Velde, MD, PhD, Admir Hadzic, MD, PhD   +7 more
doaj   +1 more source

Assessment of the Safety and Efficiency of a Preperitoneal Continuous Infusion Using Bupivacaine after Abdominal Laparotomy in Digestive Carcinology

Anesthesiology Research and Practice, 2023
The purpose of this paper is to evaluate the safety and efficacy of continuous preperitoneal wound infiltration using bupivacaine after abdominal laparotomy in relation to plasma bupivacaine concentration and visual analog scale.
Hayat Ben-Saghroune, Mohammed Abdessadek, Sanae Achour, Youssef Kfal, Abderrahim El Bouazzaoui, Nabil Kanjaa, Hicham Sbai   +6 more
doaj   +1 more source

The quaternary lidocaine derivative QX-314 in combination with bupivacaine for long-lasting nerve block: Efficacy, toxicity, and the optimal formulation in rats. [PDF]

PLoS ONE, 2017
OBJECTIVE:The quaternary lidocaine derivative (QX-314) in combination with bupivacaine can produce long-lasting nerve blocks in vivo, indicating potential clinical application. The aim of the study was to investigate the efficacy, safety, and the optimal
Qinqin Yin, Jun Li, Qingshan Zheng, Xiaolin Yang, Rong Lv, Longxiang Ma, Jin Liu, Tao Zhu, Wensheng Zhang   +8 more
doaj   +1 more source

Post-operative pain and analgesic requirements after paravertebral block for mastectomy: A randomized controlled trial of different concentrations of bupivacaine and fentanyl

Indian Journal of Anaesthesia, 2012
Background: Paravertebral block (PVB) is useful for post-operative analgesia after breast surgery. Bupivacaine is used for PVB at higher concentrations (0.5%), which may lead to systemic toxicity after absorption.
V Bhuvaneswari, Jyotsna Wig, Preethy J Mathew, Gurpreet Singh   +3 more
doaj   +1 more source

Neurotoxicity of bupivacaine and liposome bupivacaine after sciatic nerve block in healthy and streptozotocin-induced diabetic mice

BMC Veterinary Research, 2020
Background Long-acting local anaesthetics (e.g. bupivacaine hydrochloride) or sustained-release formulations of bupivacaine (e.g. liposomal bupivacaine) may be neurotoxic when applied in the setting of diabetic neuropathy.
Liljana Markova, Nejc Umek, Simon Horvat, Admir Hadžić, Max Kuroda, Tatjana Stopar Pintarič, Vesna Mrak, Erika Cvetko   +7 more
doaj   +1 more source

Analgesia Quality and Duration of Fentanyl and Sufentanil Added to Bupivacaine in Spinal Anesthesia in Inguinal Hernia Surgery: A Double‐Blind Parallel Randomized Controlled Trial

Health Science Reports
Background and Aims To compare the quality and duration of analgesia provided by Fentanyl and Sufentanil when added to 12–15 mg Bupivacaine 0.5% in spinal anesthesia for inguinal hernia surgery.
Haniyeh Soleimany, Hamed Tavan, Ebrahim Khalighi, Reza Pakzad   +3 more
doaj   +1 more source

Are reinfusion drains safe to use with periarticular liposomal bupivacaine? An analysis of systemic bupivacaine toxicity

Arthroplasty Today, 2018
Background: Intraoperative periarticular injection (PAI) with local anesthetic is an important component of multimodal pain control in total joint arthroplasty (TJA).
Marc R. Angerame, MD, Gavin P. Hart, MD, Susan M. Odum, PhD, Bryan D. Springer, MD   +3 more
doaj   +1 more source

Bupivacaine-induced apoptosis independently of WDR35 expression in mouse neuroblastoma Neuro2a cells

BMC Neuroscience, 2012
Background Bupivacaine-induced neurotoxicity has been shown to occur through apoptosis. Recently, bupivacaine was shown to elicit reactive oxygen species (ROS) production and induce apoptosis accompanied by activation of p38 mitogen-activated protein ...
Harato Misako, Huang Lei, Kondo Fumio, Tsunekawa Koji, Feng Guo-Gang, Fan Jun-Hua, Ishikawa Naohisa, Fujiwara Yoshihiro, Okada Shoshiro   +8 more
doaj   +1 more source

The safety of liposome bupivacaine following various routes of administration in animals

Journal of Pain Research, 2015
Girish P Joshi,1 Gary Patou,2 Vladimir Kharitonov21Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical School, Dallas, TX, 2Pacira Pharmaceuticals, Inc., Parsippany, NJ, USABackground: This report presents results ...
Joshi GP, Patou G, Kharitonov V
doaj  

Buprenorphine with Bupivacaine 0.5% Heavy Versus Clonidine with Bupivacaine 0.5% Heavy Versus Bupivacaine 0.5% Heavy Alone in Patients Undergoing Total Abdominal Hysterectomy: A Comparative Study

Apollo Medicine
Background and Aims: This research aimed to determine which of three spinal anaesthetic medication combinations—clonidine–bupivacaine, buprenorphine–bupivacaine and bupivacaine alone—is the most effective for total abdominal hysterectomy.
Pradeesh Johny Thankaraj, Gauthamabuddha Pranavadhyani, Rajesh Prabhu Chandrasekaran   +2 more
doaj   +1 more source