Results 21 to 30 of about 30,299 (192)
BMC Pharmacology and Toxicology, 2021 Background Bupivacaine blocks many ion channels in the heart muscle, causing severe cardiotoxicity. Small-conductance calcium-activated potassium type 2 channels (SK2 channels) are widely distributed in the heart cells and are involved in relevant ...
Hongfei Chen +3 more
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The effect of adjuvant midazolam compared with fentanyl on the duration of spinal anesthesia with 0.5% bupivacaine in opium abusers [PDF]
Korean Journal of Anesthesiology, 2012 BackgroundThere are a number of adjuvants to be used for local anesthetics in spinal block. The aim of this study was to demonstrate the possible effect of intrathecal midazolam compared with bupivacaine as adjuvants in spinal anesthesia with bupivacaine
Farhad Safari +2 more
doaj +1 more source
Advances in Pharmacological and Pharmaceutical Sciences, 2020 Objective. The purpose of this study is to determine whether (1) liposomal bupivacaine is chondrotoxic; (2) the chondrotoxicity of liposomal bupivacaine differs from standard bupivacaine; and (3) chondrotoxic effects are time dependent.
Travis Farmer +5 more
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Gynecologic Oncology Reports, 2023 Background: To evaluate whether incisional infiltration of liposomal bupivacaine would decrease opioid requirement and pain scores after midline vertical laparotomy for suspected or known gynecologic malignancy compared with transversus abdominis plane ...
Ashley S. Moon +7 more
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Liposomal bupivacaine reduces opioid requirements following Ravitch repair for pectus excavatum
Journal of Anaesthesiology Clinical Pharmacology, 2023 Background and Aims: The management of post-operative pain after surgical repair of pectus excavatum with the Ravitch procedure is challenging. Although previous studies have compared various methods of pain control in these patients, few have compared ...
Rania K Abbasi +6 more
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Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication. [PDF]
PLoS ONE, 2018 In order to determine the role of the adrenergic system in bupivacaine-induced cardiotoxicity, a series of experiments were performed. In an animal experiment, male Sprague-Dawley (SD) rats under chloral hydrate anesthesia received intravenous ...
Jun Li +11 more
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Direct Vasocontractile Activities of Bupivacaine Enantiomers on the Isolated Rat Thoracic Aorta
Anesthesiology Research and Practice, 2010 Background. In vitro studies with isolated arteries have shown direct vasoactivity of racemic bupivacaine. However, there is little information on the direct vasoactivities of bupivacaine enantiomers, S(−)- and R(+)-bupivacaine. Methods.
Mai Mukozawa, Ko Takakura, Maki Mizogami
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Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Objective During the surgical procedure of deep brain stimulation (DBS), insertion of an electrode in the subthalamic nucleus (STN) frequently causes a temporary improvement of motor symptoms, known as the microlesion effect (MLE). The objective of this study was to determine the correlation between the intraoperative MLE and the clinical ...
Stèfan F. Lange +8 more
wiley +1 more source
Comparison of Equivalent Doses of Intrathecal Hyperbaric Levo-bupivacaine and Hyperbaric Bupivacaine for Caesarean Section: A Prospective Randomised Double-Blind Study [PDF]
Journal of Clinical and Diagnostic ResearchIntroduction: Subarachnoid Block (SAB) with Hyperbaric Bupivacaine (HB) is the most common anaesthetic technique for Lower Segment Caesarean Section (LSCS). Levo-bupivacaine, an enantiomer of racemic bupivacaine, has been developed to provide anaesthesia
Noyomi Saring +3 more
doaj +1 more source