Results 41 to 50 of about 39,408 (252)

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Comparison of the Maternal and Neonatal Effects of Intratechal Bupivacaine Plus Fentanyl or Morphine During Cesarean Delivery

, 2016
Aim: To evaluate the effects of morphine and fentanyl added to bupivacaine and intrathecal bupivacaine to combine spinal-epidural anaesthesia during caesarean. Methods: Forty subjects with American Society of Anesthesiologists I-II status who would have
Gülşen Bosna, Ferhunde Dilek Subaşı, Ahmet Yıldırım, Osman Ekinci, Güldem Turan, Yıldız Kuplay   +5 more
core   +1 more source

0.5% Bupivacaine vs 0.25% Bupivacaine vs Mepivacaine/Bupivacaine: Comparison of 3 local anesthetic regimens used in nerve blocks

, 2022
Nerve blocks are a vital component of postoperative pain management. There are many local anesthetics (LA) that are utilized in nerve blocks. This study aims to gather information regarding the efficacy of 0.5% Bupivacaine vs 0.25% Bupivacaine vs ...
Michael Lange, Kelsea Ice NP, Yar (Samantha) Yeap MD   +2 more
core   +1 more source

Efficacy of dexamethasone as an adjuvant to bupivacaine in supraclavicular brachial plexus block

Journal of Gandaki Medical College, 2022
Introduction: Supraclavicular brachial plexus block provides the optimal operating conditions for upper arm surgery. The study was conducted to assess the efficacy of dexamethasone as an adjuvant to bupivacaine in supraclavicular brachial plexus block.
Sagun Ram Vaidya, Sandeep Neupane, Kundu Shrestha, Tumaya Ghale   +3 more
doaj   +1 more source

Targeted senotherapy improves electrographic and behavioral outcomes in a mouse model of temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Current pharmacotherapy for temporal lobe epilepsy (TLE) is limited to symptomatic treatment and leaves approximately one third of patients with inadequate seizure control. Discovering disease‐modifying targets is an unmet clinical need. We have previously identified senescent cells (SCs) as one such target. Many drugs that eliminate
David J. McFall, Abbas I. Hussain, Michelle Cho, Patrick A. Forcelli   +3 more
wiley   +1 more source

Arterial Perivascular Space‐Mediated Solute Transport in the Mouse Brain

Exploration, EarlyView.
The mechanisms underlying solute clearance from the brain parenchyma remain debated, with competing hypotheses involving bulk cerebrospinal fluid flow versus perivascular transport. Using multimodal in vivo imaging and computational modeling in mice, this study demonstrates that arterial pulsation drives bidirectional solute movement within the ...
Shiyong Li, Ye Wang, Guangyu Jia, Yamei Yu, Zhe Zhang, Qi Wang, Kaelyn V. Becker, Jonathan W. Engle, Dawei Jiang, Weibo Cai   +9 more
wiley   +1 more source

Buprenorphine with Bupivacaine 0.5% Heavy Versus Clonidine with Bupivacaine 0.5% Heavy Versus Bupivacaine 0.5% Heavy Alone in Patients Undergoing Total Abdominal Hysterectomy: A Comparative Study

Apollo Medicine
Background and Aims: This research aimed to determine which of three spinal anaesthetic medication combinations—clonidine–bupivacaine, buprenorphine–bupivacaine and bupivacaine alone—is the most effective for total abdominal hysterectomy.
Pradeesh Johny Thankaraj, Gauthamabuddha Pranavadhyani, Rajesh Prabhu Chandrasekaran   +2 more
doaj   +1 more source

Comparative study of epidural administration of 10 ml of 0.1% bupivacaine with 2 mg butorphanol and 10 ml of 0.25% plain bupivacaine for analgesia during labor

Journal of Nepal Medical Association, 2007
Analgesia during labor provided by two epidural drug regimens was compared in a double blind, randomized, prospective study. Group A (n = 12) received 10 ml bolus doses of 0.1% bupivacaine with butorphanol 2 mg while Group B (n = 8) received 10 ml of 0 ...
CK Shrestha, KR Sharma, RR Shrestha
doaj   +1 more source

Lower Dosing of Bupivacaine Spinal Anesthesia Is Not Associated With Improved Perioperative Outcomes After Total Joint Arthroplasty

Arthroplasty Today, 2021
Background: The choice of anesthesia plays a significant role in the success of total joint arthroplasty (TJA). Isobaric bupivacaine spinal anesthesia is often used.
Carl L. Herndon, MD, Matthew M. Levitsky, MD, Chimere Ezuma, BS, Nana O. Sarpong, MD, MBA, Roshan P. Shah, MD, JD, H. John Cooper, MD   +5 more
doaj   +1 more source

Analgesia pós-operatória em pacientes submetidas a videolaparoscopias ginecologias com uso pré-operatório de anestésico local no sítio de inserção dos tocartes: ensaio clínico randomizado. [PDF]

, 2009
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Stefanon, Tiago
core