Results 51 to 60 of about 30,299 (192)

Efficacy and safety of different bupivacaine concentrations in periarticular infiltration combined with adductor canal block for bilateral total knee arthroplasty: a randomized controlled trial

Knee Surgery & Related Research
Background Pain management for bilateral total knee arthroplasty (BTKA) often combines adductor canal block (ACB) with periarticular infiltration (PAI). However, concerns arise regarding local anesthetic toxicity.
Sukanya Dej-arkom, Pawinee Pangthipampai, Weerawadee Chandranipapongse, Somruedee Chatsirichareonkul, Rapeepat Narkbunnam, Keerati Charoencholvanich, Suwida Tangchittam, Arissara Iamaroon   +7 more
doaj   +1 more source

Interscalene nerve block with plain bupivacaine versus liposomal bupivacaine for arthroscopic rotator cuff repair: A randomized controlled trial

Saudi Journal of Anaesthesia
Background: Although single injections with anesthetics are commonly administered given their safety, their short-acting nature limits pain control.
Paul Sang Lee, Yasuko M. Mano, Brian M. Hom, Ioanna K. Bolia, Roy P. Yu, Alexander Weber, Seth Gamradt, Beamy Sharma, Gligor Gucev   +8 more
doaj   +1 more source

Preoperative caudal blocks associated with decreased cumulative opioid requirements compared to postoperative caudal blocks in pediatric urologic surgery

UroPrecision, EarlyView.
Abstract Background Caudal blocks (CB) are a cornerstone of pediatric urologic surgery, providing effective analgesia while mitigating potential neurotoxicity associated with general anesthesia and opioids. However, the optimal timing of CB—preoperative versus postoperative—remains controversial.
Jordan L. Mendelson, William Brenseke, Diego Alvarez Vega, William Nguyen, Mohammed Shium, Saige Gitlin, Ronnie G. Fine, Steven C. Friedman, Mark Horowitz, Walter I. Weiss, Raghu Idupuganti, Jordan S. Gitlin   +11 more
wiley   +1 more source

Limited Clinical Impact of Androgen Receptor Repeat Length (CAG and GGC) in Klinefelter Syndrome: A Multivariable Analysis

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS) is characterized by marked phenotypic heterogeneity that might be influenced by genetic modifiers, including androgen receptor (AR) repeat length (CAGn and GGCn). The clinical relevance of these repeat lengths in patients with KS before testosterone replacement therapy (TRT) remains unclear.
Andrea Graziani, Alberto Scala, Maria Santa Rocca, Cinzia Vinanzi, Giuseppe Grande, Andrea Di Nisio, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +8 more
wiley   +1 more source

An evaluation of the analgesic effect of AnestaGel™ on mechanical allodynia in a rat model of postoperative incisional pain

Journal of Pain Research, 2017
Jacob Hutchins,1 William Taylor2 1Department of Anesthesiology, University of Minnesota, Minneapolis, MN, USA; 2InSitu Biologics, LLC, St Paul, MN, USA Purpose: Sustained release hydrogel with bupivacaine (AnestaGel™) is a novel formulation of ...
Hutchins J, Taylor W
doaj  

Impact of FSHB and FSHR Genes Polymorphisms on Hormonal Profile and Sperm Retrieval Outcome in Men With Klinefelter Syndrome: A Clinical–Genetic Predictive Study

Andrology, EarlyView.
ABSTRACT Background Genetic variability within the follicle‐stimulating hormone (FSH)‐related genes might contribute to phenotypic heterogeneity in patients with Klinefelter syndrome (KS), yet its clinical impact on sperm retrieval remains unclear. Objectives To investigate the association between FSHB c.211 G > T and FSHR polymorphisms (c.2039 A > G ...
Andrea Graziani, Giuseppe Grande, Maria Santa Rocca, Massimo Iafrate, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +6 more
wiley   +1 more source

Efficacy of low dose bupivacaine with intrathecal fentanyl for cesarean section on maternal hemodynamic: Systemic review and meta-analysis

Saudi Journal of Anaesthesia, 2019
Hypotension during spinal Anesthesia is the most common complication with maternal and neonatal morbidity and mortality. Low dose bupivacaine with intrathecal fentanyl is recommended as strategy to prevent spinal Anesthesia induced hypotension and ...
Semagn Mekonnen Abate, Akine Eshete Belihu   +1 more
doaj   +1 more source

Shoulder‐Tip Pain After Laparoscopic Surgery: A Narrative Review of Intraperitoneal Anaesthesia

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background and Aims Shoulder‐tip pain is a common and distressing side effect following laparoscopic surgery. Standard systemic analgesic regimens are used to manage postoperative pain but are often associated with side effects such as nausea and vomiting.
Jason Arsanious, Alice Osterwalder, Sarah K. Thompson   +2 more
wiley   +1 more source

Alkalinised lidocaine as an anaesthetic before onabotulinumtoxinA injections. a randomised trial

BJU International, Volume 135, Issue 4, Page 638-647, April 2025.
Objectives To evaluate the effect of intravesical alkalinised lidocaine as an anaesthetic treatment on procedural pain during intradetrusor onabotulinumtoxinA (BTX‐A) injections for overactive bladder. Patients and Methods This single‐centre, randomised, double‐blind, placebo‐controlled two period crossover trial was conducted on women scheduled for ...
Meryam El Issaoui, Marlene Elmelund, Niels Klarskov   +2 more
wiley   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source