Results 51 to 60 of about 57,563 (245)

Targeted senotherapy improves electrographic and behavioral outcomes in a mouse model of temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Current pharmacotherapy for temporal lobe epilepsy (TLE) is limited to symptomatic treatment and leaves approximately one third of patients with inadequate seizure control. Discovering disease‐modifying targets is an unmet clinical need. We have previously identified senescent cells (SCs) as one such target. Many drugs that eliminate
David J. McFall, Abbas I. Hussain, Michelle Cho, Patrick A. Forcelli   +3 more
wiley   +1 more source

The safety of liposome bupivacaine following various routes of administration in animals

Journal of Pain Research, 2015
Girish P Joshi,1 Gary Patou,2 Vladimir Kharitonov21Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical School, Dallas, TX, 2Pacira Pharmaceuticals, Inc., Parsippany, NJ, USABackground: This report presents results ...
Joshi GP, Patou G, Kharitonov V
doaj  

Combination of magnesium sulphate and ropivacaine epidural analgesia for hip arthroplasty in dogs [PDF]

, 2017
The aim of this study was to determine whether lumbosacral epidural administration of magnesium sulphate added to ropivacaine prolongs and improves perioperative analgesia, without adverse effects on motor block duration or hind limb neurological ...
Adami, C, Lardonea, E, Peironea, B
core   +2 more sources

External cephalic version outcomes with tocolysis and sedation: A 10‐year retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate the effectiveness and safety of external cephalic version (ECV) performed with tocolysis and sedation or spinal anesthesia, and to identify predictors of ECV success, complications, and delivery outcomes after successful ECV. Methods This 10‐year cohort study included 990 pregnant women with term non‐cephalic presentation
Javier Sánchez‐Romero, Rosa María Gallego‐Pozuelo, José Eliseo Blanco‐Carnero, Javier Herrera‐Giménez, Fernando Araico‐Rodríguez, Alberto Rafael Guijarro‐Campillo, Aníbal Nieto‐Díaz, Catalina de Paco‐Matallana   +7 more
wiley   +1 more source

Case Report and Literature Review: Interventional Management of Erythromelalgia. [PDF]

, 2019
Erythromelalgia is a rare and very difficult to treat pain syndrome that usually presents as severe bilateral burning pain in the extremities. Here we present a case of a 34-year-old female with erythromelalgia who we treated successfully with a lumbar ...
Chinn, Gregory, Guan, Zhonghui
core  

Ultrasound‐Guided Liposomal vs. Conventional Bupivacaine Erector Spinae Plane Block Plus Gabapentin for Postherpetic Neuralgia

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to compare efficacy and safety of ultrasound‐guided erector spinae plane block (ESPB) using liposomal (LB) versus conventional bupivacaine (CB), each plus standardized gabapentin, in patients with postherpetic neuralgia (PHN). A total of 116 PHN patients were randomized to ESPB‐LB or ESPB‐CB; both groups received standardized ...
Xia‐Jing Xu, Li‐Juan Liu, Fa‐Ming Xu, Xiang‐Yu Fang   +3 more
wiley   +1 more source

Interscalene nerve block with plain bupivacaine versus liposomal bupivacaine for arthroscopic rotator cuff repair: A randomized controlled trial

Saudi Journal of Anaesthesia
Background: Although single injections with anesthetics are commonly administered given their safety, their short-acting nature limits pain control.
Paul Sang Lee, Yasuko M. Mano, Brian M. Hom, Ioanna K. Bolia, Roy P. Yu, Alexander Weber, Seth Gamradt, Beamy Sharma, Gligor Gucev   +8 more
doaj   +1 more source

Bupivacaine (0.5%) Versus (0.5%) Bupivacaine with Ketamine (50 mg) for Subarachnoid Block in Lower Abdominal Surgeries: A Randomised Comparative Study [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Spinal anaesthesia is the preferred technique for most of the lower abdominal surgeries nowadays. Currently, Bupivacaine is the most commonly used drug in spinal anaesthesia.
Bhargav Vishnu Gantasala, Amol Singam, Karuna Talsande   +2 more
doaj   +1 more source

Ultrasound-Guided Lateral Femoral Cutaneous Nerve Cryoneurolysis for Analgesia in Patients With Burns. [PDF]

, 2020
Autologous skin grafting from the thigh is frequently required for treatment of burns and is associated with intense pain at the donor site. Local anesthetic-based (LA) nerve blocks of the lateral femoral cutaneous nerve (LFCN) have been demonstrated to ...
Fiallo, Alfredo, Finneran, John J, Gabriel, Rodney A, Hamilton, Jeffrey R, Ilfeld, Brian M, Lee, Jeanne G, Swisher, Matthew W   +6 more
core  

ALT Rescue Flap With Iliac Crest Bone Graft and Spanning Plate for Mandibular ORN

The Laryngoscope, EarlyView.
In select patients with focal full‐thickness mandibular ORN defects, the use of ALTFL in conjunction with ICBG and a spanning reconstructive plate appears to offer clinical and radiographic arrest of ORN. This technique has considerably lower morbidity than osteocutaneous reconstruction, with abbreviated hospital stays, a low complication rate, and no ...
Derek J. Vos, Sara W. Liu, Peter J. Ciolek, Brandon L. Prendes, Michael A. Fritz   +4 more
wiley   +1 more source