Results 271 to 280 of about 63,586 (320)

Dexmedetomidine and Propofol Sedation in Critically Ill Patients and Dose Associated 90-day Mortality: A Secondary Cohort Analysis of a Randomized Controlled Trial (SPICE-III).

American Journal of Respiratory and Critical Care Medicine, 2022
RATIONALE Sedation Practice in Intensive Care Evaluation (SPICE-III) trial reported significant heterogeneity in mortality with dexmedetomidine treatment. Supplemental propofol was commonly used to achieve desirable sedation. OBJECTIVES to quantify the
Y. Shehabi   +13 more
semanticscholar   +1 more source

Dexmedetomidine for dyspnoea

BMJ Supportive & Palliative Care, 2020
Dexmedetomidine is a selective α2-adrenoreceptor agonist with a broad range of effects, including easily controllable sedation, analgesia and anxiolysis. Because of these favorable features, it has replaced traditional sedatives, such as benzodiazepines, and is becoming the first-line sedative for the patients in intensive care units.
Akiko Mano   +8 more
openaire   +3 more sources

The potential role of dexmedetomidine on neuroprotection and its possible mechanisms: Evidence from in vitro and in vivo studies

European Journal of Neuroscience, 2021
Neurological disorders following brain injuries and neurodegeneration are on the rise worldwide and cause disability and suffering in patients. It is crucial to explore novel neuroprotectants.
K. Unchiti   +5 more
semanticscholar   +1 more source

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