Results 71 to 80 of about 1,568 (202)

Targeting Glutamate Excitotoxicity With Memantine Modulates Glial Response and Protects Motoneurons After Spinal Root Lesion

open access: yesJournal of Neurochemistry, Volume 170, Issue 4, April 2026.
Motoneuron axotomy induced marked neuroinflammation, synaptic withdrawal, and structural remodeling in the ventral root crush (VRC) model, characterized by intense microglial and astroglial activation and reduced synaptic coverage. Memantine treatment produced consistent, dose‐dependent neuroprotection, with maximal effects at 45 mg/kg.
Arthur Ventura Martins Leão   +3 more
wiley   +1 more source

Is it possible to prevent contrast-induced nephropathy with dexpanthenol?

open access: yesInternational Urology and Nephrology, 2019
Contrast-induced nephropathy (CIN) is one of the side effects of diagnostic procedures. Oxidative stress plays an important role in CIN's pathophysiology. Dexpanthenol (Dexp) is a substance with antioxidant efficacy. We investigated the likely protective effects of dexpanthenol for CIN.Twenty-four Sprague-Dawley rats were divided randomly into four ...
IŞIK GÖNÜL, İPEK   +7 more
openaire   +6 more sources

Cosmetic Interventions for Skin Microbiome Modulation: Current Strategies and Future Directions

open access: yesSkin Research and Technology, Volume 32, Issue 4, April 2026.
ABSTRACT Background Human skin harbors a highly diverse and dynamic microbiome that maintains barrier function and homeostasis, while endogenous/exogenous factors and cosmetic products modulate microbial balance. Dysbiosis contributes to inflammatory diseases like atopic dermatitis and acne; however, evidence for microbiome‐targeted cosmetics remains ...
Raquel Taléns‐Visconti   +2 more
wiley   +1 more source

Dexpanthenol reduces fibrosis and aids repair following nerve laceration and neurorrhaphy

open access: yes, 2021
The aim of the present study was to investigate the effect of dexpanthenol on nerve healing following neurorrhaphy in lacerated peripheral nerves. A total of 30 mature Sprague Dawley rats were used.
Yiğittürk, Gürkan   +5 more
core   +1 more source

The Effect of Dexpanthenol in Postoperative Patients

open access: yesJournal of the Korean Society of Coloproctology, 2007
Purpose: The purpose of this study was to compare the efficacy of dexpanthenol in postoperative patients. Dexpanthenol, the alcohol derivative of pantothenic acid, is believed to be a precursor of acetylcholine through its incorporation into coenzyme-A.
Mi Ri Hwang   +3 more
openaire   +1 more source

Prevention of Atopic Dermatitis in High‐Risk Infants: A Review of the Role of Lipid‐Based Barrier Repair Therapy

open access: yesPediatric Dermatology, Volume 43, Issue 2, Page 237-250, March/April 2026.
ABSTRACT Background/Objective Growing evidence highlights the role of physiological lipids, namely ceramides, cholesterol, and free fatty acids, in maintaining skin barrier function and preventing atopic dermatitis (AD). Current evidence on the efficacy, safety, and clinical relevance of stratum corneum (SC) lipid‐based therapies to prevent AD and ...
Chon‐Wai Jeremy Chan   +1 more
wiley   +1 more source

Evaluation of beneficial effects of dexpanthenol on hypoxic-ischemic encephalopathy

open access: yes
Hypoxic-ischemic encephalopathy (HIE) is a cause of serious morbidity and mortality in newborns. Dexpanthenol, which is metabolized into D-pantothenic acid, has antioxidant and other potentially therapeutic properties.
Çağlayan, Murat   +6 more
core   +1 more source

Optoacoustic‐Guided Magnetic Microrobot Platform for Precision Drug Delivery

open access: yesAdvanced Materials, Volume 38, Issue 5, 22 January 2026.
Optoacoustically guided FePt@ZIF‐8‐based microrobots are designed with high drug loading capacity, controllable locomotion, and deep‐tissue imaging capability. By integrating navigation, drug release, and real‐time monitoring into a single platform, they provide a versatile tool for precise intervention, opening new possibilities for treating ...
Fan Wang   +12 more
wiley   +1 more source

Postoperative sore throat: a systematic review*

open access: yesAnaesthesia, Volume 81, Issue 1, Page 116-133, January 2026.
Summary Introduction Postoperative sore throat is a common complaint with an incidence of up to 62%. While anaesthetists often perceive this as a minor and self‐limiting complication, postoperative sore throat is one of the leading causes of postoperative anaesthesia‐related discomfort.
Zachary J. Moulder   +4 more
wiley   +1 more source

Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats

open access: yes, 1993
Aim Although the most common age-related neurodegenerative disease defined by memory loss is Alzheimer's disease (AD), only symptomatic therapies are present.
Erbas, Oytun   +4 more
core   +1 more source

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