Results 161 to 170 of about 201,008 (300)

Inorganic Nanomaterials can Promote or Inhibit Tumor Metastasis Depending on Tumor Microenvironment Composition

Advanced Science, EarlyView.
As engineered nanomaterials gain prominence in cancer imaging and therapy, understanding their impact on tumor progression becomes increasingly critical. We demonstrate that gold and silica‐coated gold nanomaterials can either suppress or enhance breast cancer metastasis through distinct tumor microenvironment interactions, while identifying ...
Kiana Buttiens, Xiaoqi Zheng, Xueqi Fan, Mukaddes Izci, Christy Maksoudian, Irati Perez Gilabert, Tianjiao Chu, Filipa Goncalves, Jonas Dehairs, Johan Swinnen, Bella B. Manshian, Stefaan J. Soenen   +11 more
wiley   +1 more source

Systemic Evaluation of Administered FITC-Dextran or Evans Blue Dye to Determine Intestinal Barrier Permeability in Nonhuman Primates. [PDF]

Pathog Immun
Bodykevich EG, Vinton CL, Ortiz AM, Brenchley JM.   +3 more
europepmc   +1 more source

Nano Proton Scavengers Modulate Endosomal pH to Inhibit Microglial Activation and Enhance Stroke Recovery

Advanced Science, EarlyView.
Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang, Yujing Shi, Zehua Gao, Jing Wang, Changsheng Liu   +4 more
wiley   +1 more source

One-pot synthesis of dextran-coated iron oxide nanoclusters for real-time regional lymph node mapping

, 2017
Chaoping Fu,1,* Haipeng Zhou,2,* Yanan Wang,2,* Dong Liu,2 Junmeng Li,2 Haijun Deng,2 Xiaolong Qi,2 Tao Chen,2 Li-Ming Zhang,1 Guoxin Li2 1PCFM Lab and GDHPPC Lab, School of Materials Science and Engineering, Sun Yat-sen University, 2Department of ...
Zhang LM, Li G, Fu C, Li J, Qi X, Wang Y, Liu D, Zhou H, Deng H, Chen T   +9 more
core  

Structural and functional characterisation of the dextran utilisome from <i>Bacteroides thetaiotaomicron</i>. [PDF]

J Struct Biol X
Feasey M, Silale A, Baslé A, van den Berg B.   +3 more
europepmc   +1 more source

Defect‐Engineered BiO2‐X Nanosheets Mediate Sono‐Thermomechanical ECM Remodeling for Hepatocellular Carcinoma Immunotherapy

Advanced Science, EarlyView.
Herein, an ultrasound‐responsive BiO2‐X/siFn1 nanoplatform is developed to overcome anti‐PD‐1 resistance in hepatocellular carcinoma. Upon ultrasound irradiation, the platform downregulates fibronectin expression, while its sonothermal effect softens the dense extracellular matrix and activates antitumor immunity in the tumor microenvironment, thereby ...
Huimin Tian, Shen Zhang, Bolin Wu, Yichi Chen, Haitao Shang, Haoyan Tan, Chunyue Wang, Weichen Xu, Huixiong Xu, Haohao Yin, Wen Cheng   +10 more
wiley   +1 more source

Chronic Smoking Impairs Glymphatic Transport and Cognitive Function in Adolescent Mice Through Cardiac, Vascular, and Perivascular Aquaporin-4 Mechanisms. [PDF]

CNS Neurosci Ther
Lv C, Xia C, Li Z, Liu T, Sha Z, Dong S, Qian Y, Liu M, Zhang K, Zhang X, Jiang R, Bie L.   +11 more
europepmc   +1 more source

Atmospheric Water Harvesting Through Polymer Hydrogel Sorbents: Materials Chemistry, Design Strategies, and Applications

Advanced Science, EarlyView.
Polymer‐based hydrogels have emerged as promising materials for atmospheric water harvesting (AWH) due to their high water affinity, tunable network structure, and excellent moisture adsorption‐desorption performance. Functional hydrogel systems enable efficient water capture and controlled release under low‐energy conditions, offering a sustainable ...
Swagata Datta, Sushmit Sen, Nilanjan Dey, Amrita Chatterjee, Ananya Sadhu, Sudipta Sarkar, Pradip K. Maji   +6 more
wiley   +1 more source

Engineering dextranase for the directed preparation of low-molecular-weight dextran. [PDF]

Food Chem (Oxf)
Qin Y, Ren Y, Tong L, Liang G, Yuan Y, Meng L, Zhang H, Wang Q.   +7 more
europepmc   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source