Results 111 to 120 of about 12,421 (291)

ENZYMATIC DEGRADATION OF POLY(ETHYLENE GLYCOL) MODIFIED DEXTRANS

open access: yes, 2009
[[abstract]]©1994 Sagepub - Poly(ethylene glycol) (PEG), with molecular weight 2,000 and 5,100, were conjugated to dextran (T-40) with three different degrees of substitution.
CHIU HC;KONAK C;KOPECKOVA P;KOPECEK J
core  

The use of dextrans as particulate tracers in respiratory epithelial permeability studies

open access: yes, 1981
These experiments were designed to test the suitability of dextrans as alternate light and electron microscopic tracers to horseradish peroxidase (HRP) in studies of respiratory epithelial permeability in control and cigarette smoke-exposed guinea pigs ...
Forster, Allan Bruce Burton
core   +1 more source

Covalently Linked Peptides and Membrane Potential Enable CyaA Segment Translocation

open access: yesAdvanced Science, EarlyView.
Using a newly developed Droplet Interface Bilayer‐Pipette assay, the authors show that two segments of the CyaA toxin cross membranes by distinct mechanisms. One segment translocates spontaneously, whereas the translocation of the other depends on membrane potential.
Gaia Scilironi   +9 more
wiley   +1 more source

Effect of Catechol Content in Catechol-Conjugated Dextrans on Antiplatelet Performance

open access: yes, 2017
The surface coating of solid substrates using dextrans has gained a great deal of attention, because dextran-coated surfaces show excellent anti-fouling property as well as biocompatibility behavior. Much effort has been made to develop efficient methods
Kwang-A Kim, Sung Kang, Yeonwoo Jeong
core   +1 more source

Programmed Interfacial Phase Separation for Spatiotemporal Fungicide Delivery via Tunable Micro/Nano Architectures

open access: yesAdvanced Science, EarlyView.
ABSTRACT Translating dynamic liquid‐liquid phase separation into robust solid‐state architectures remains a challenge in materials engineering. Here, we report a composition‐driven interfacial assembly strategy that couples supramolecular coacervation with metal‐phenolic coordination to engineer tunable fungicide carriers.
Rui Zhang   +7 more
wiley   +1 more source

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

open access: yesAdvanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang   +6 more
wiley   +1 more source

Characterization of dextrans produced by Lactobacillus mali CUPV271 and Leuconostoc carnosum CUPV411

open access: yes, 2019
35 p.-14 fig.-4 tab.The exopolysaccharide (EPS)-producing Lactobacillus mali CUPV271 and Leuconostoc carnosum CUPV411 were isolated from Spanish ropy apple must and slimy ham, respectively. The polymers were purified from bacterial cultures’ supernatants
Marieta, Cristina   +8 more
core   +1 more source

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

open access: yesAdvanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu   +10 more
wiley   +1 more source

Inhibition by heparin and derivatized dextrans of Staphylococcus aureus adhesion to fibronectin-coated biomaterials

open access: yes, 1992
Recent data on cardiovascular device-centered infections suggest that some plasma and extracellular matrix proteins contribute to bacterial adhesion and colonization on biomaterials.
Lew, Daniel Pablo   +4 more
core   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang   +8 more
wiley   +1 more source

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