The toxicokinetic profile of Dex40-GTMAC3 : a novel polysaccharide candidate for reversal of unfractionated heparin [PDF]
, 2016 Though protamine sulfate is the only approved antidote of unfractionated heparin (UFH), yet may produce life threatening side effects such as systemic hypotension, catastrophic pulmonary vasoconstriction or allergic reactions.
Błażejczyk, Agnieszka +10 more
core +2 more sources
Bioengineered 3D hPSC‐Cholangiocyte Ducts With Physiological Signals for Biliary Disease Modeling
Advanced Healthcare Materials, EarlyView.Tian and colleagues generated a bioengineered bile duct from human pluripotent stem cell (hPSC)‐derived intrahepatic cholangiocytes within a high‐throughput, 384‐well platform to systematically examine the influence of biliary physiological signals including fluid flow, stromal cells and bile acids, and models intrahepatic biliary disease progression ...
Britney Tian +10 more
wiley +1 more source
Aqueous Humor Outflow Structure and Function Imaging At the Bench and Bedside: A Review. [PDF]
, 2016 Anterior segment glaucoma clinical care and research has recently gained new focus because of novel imaging modalities and the advent of angle-based surgical treatments. Traditional investigation drawn to the trabecular meshwork now emphasizes the entire
Huang, Alex S +2 more
core +1 more source
Advanced Healthcare Materials, EarlyView.This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan +12 more
wiley +1 more source
Factors that Interfere in Dextran Production By Sugarcane Contaminating Microorganisms
Semina: Ciências Exatas e Tecnológicas, 2002 Dextrans are polysaccharides produced by microorganisms, specially bacterias from the Leuconostoc genus. Dextrans have a high molecular weigh and most of the glycosidic bonds are a(1®6).
Maria Celia Oliveira Hauly +4 more
doaj
Diffusion of alpha-Chymotrypsin in solution-crowded media. A fluorescence recovery after photobleaching study [PDF]
, 2017 Fluorescence Recovery after Photobleaching (FRAP) is one of the most powerful and used techniques to study diffusion processes of macromolecules in membranes or in bulk. Here, we study the diffusion of alpha-chymotrypsin in different crowded (Dextran) in
Cascante i Serratosa, Marta +5 more
core +1 more source
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Advanced Healthcare Materials, EarlyView.Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Dye Release Experiments with Dextran Loaded Vesicles
Bio-Protocol, 2014 Dye release experiments are a widely used method to assess the interactions between membrane-active molecules and lipid membranes. Of particular interest is the ability to assess the degree of the lipid bilayer perturbation by simultaneously ...
Marc-Antoine Sani +2 more
doaj +1 more source
Postoperative care in finger replantation. Our case-load and review of the literature [PDF]
, 2015 OBJECTIVE: Technical success of a finger replantation depends on several factors such as surgical procedure, type of injury, number of segments amputated, amputation level and individual patient factors.
Chen, Hc +6 more
core
Three-dimensional fluorescence recovery after photobleaching with the confocal scanning laser microscope [PDF]
, 2003 Confocal scanning laser microscopes (CSLMs) are equipped with the feature to photobleach user-defined regions. This makes them a handy tool to perform fluorescence recovery after photobleaching (FRAP) measurements.
Braeckmans, Kevin +4 more
core +2 more sources