Results 191 to 200 of about 80,809 (231)

Histamine release induced by dextran: The nature of the dextran receptor

European Journal of Pharmacology, 1982
Dextrans of molecular weight 10(4) to 2 x 10(6) induced histamine release from rat peritoneal mast cells in the presence of calcium (1 mM) and phosphatidyl serine (10 micrograms/ml). Glucose and low molecular weight dextrans inhibited the histamine release induced by high molecular weight dextrans but the inhibition could not be explained in terms of a
Indhrasen Moodley, John C. Foreman, Jack L. Mongar   +2 more
openaire   +2 more sources

Molecular-weight-dependent pharmacokinetics of fluorescein-labeled dextrans in rats.

Journal of Pharmacy and Science, 1992
The dependency of the pharmacokinetics of fluorescein-labeled dextrans on M(r) was studied in adult Sprague-Dawley rats. Single intravenous doses (5 mg/kg) of the dextrans with M(r) of 4000, 20,000, 40,000, 70,000, or 150,000 and single oral doses (50 mg/
R. Mehvar, T. L. Shepard
semanticscholar   +1 more source

Dextran Therapy in Thrombophlebitis

JAMA: The Journal of the American Medical Association, 1965
The value of dextran has increased far beyond that of a volume expander. Low-molecularweight fractions (average molecular weight [mol wt] 40,000) have the ability to disrupt red cell agglutination and in some states to improve blood flow 1 ; this has proved useful in ischemic and low flow situations.
Robert B. Sawyer, Peter C. Canizaro, John A. Moncrief   +2 more
openaire   +3 more sources

Synthesis of Poly(ε‐lysine)‐Grafted Dextrans and Their pH‐ and Thermosensitive Hydrogelation with Cyclodextrins

, 2005
To give pH sensitivity to a thermoreversible supramolecular-structured hydrogel system, poly(epsilon-lysine) (PL), as a cationic polymer, was grafted to dextran and used for inclusion complexation with alpha-cyclodextrins (alpha-CDs).
H. Choi, Kaori Yamamoto, T. Ooya, N. Yui
semanticscholar   +1 more source

Permeability of neutral vs. anionic dextrans in cultured brain microvascular endothelium.

American Journal of Physiology, 1990
The luminal surface of vascular endothelium contains glycocalyx residues that establish an overall negative charge. Recent evidence has suggested that local endothelial surface charge properties may account for the permeability properties of various ...
G. Sahagun, S. Moore, M. Hart
semanticscholar   +1 more source

Corneal Cryopreservation with Dextran

Cryobiology, 2001
Different methods of corneal cryopreservation have been introduced, those employing intracellular cryoprotectants such as Me2SO or glycerol being the most widely favored. We investigated the influence of several freeze-thaw trauma variables on the survival of porcine endothelial monolayers when employing the extracellular cryoprotective agent dextran ...
Michael Hagenah, M. Halberstadt, S. Athmann   +2 more
openaire   +3 more sources

Antiproliferative capacity of synthetic dextrans on smooth muscle cell growth: the model of derivatized dextrans as heparin-like polymers.

Journal of Biomaterials Science. Polymer Edition, 1993
Proliferation of vascular smooth muscle cells (SMC) is postulated to be a key step in the pathogenesis of atherosclerosis or restenosis after vascular interventions such as angioplasty. Natural glycosaminoglycans, such as heparin and heparan sulfate, are
D. Letourneur, D. Logeart, T. Avramoglou, J. Jozefonvicz   +3 more
semanticscholar   +1 more source

Toxicities of dextrans

Transfusion, 1976
Ray M. Lowenthal, John M. Goldman, D. S. Park   +2 more
openaire   +6 more sources

Anaphylactic Reaction to Dextrans

New England Journal of Medicine, 1968
DEXTRANS have been used extensively as plasma expanders1 and for the treatment of venous thrombosis and emboli,2 traumatic occlusion of vessels,3 peripheral ischemia4 and arterial emboli.5 Despite a large clinical experience with this material in Europe and America, no serious reactions have been reported.
openaire   +3 more sources

Dextran Anaphylaxis

Angiology, 1969
V I, Maddi, E M, Wyso, E N, Zinner
openaire   +2 more sources