Results 261 to 270 of about 38,524 (332)

Intestinal Neutral Ceramidase Deficiency Triggers Regulatory T Cell Response via Gd3 to Protect the Host from Intestinal Inflammation

open access: yesAdvanced Science, EarlyView.
Deletion of ASAH2 in intestinal epithelial cells induces the accumulation of ganglioside GD3 via regulating ST8SIA1. GD3 is identified as the glycolipid ligand for the inhibitory receptor Siglec‐E on macrophages. GD3/Siglec‐E ligation polarizes macrophages and promotes the proliferation of colonic ST2+ T regulatory cells via the induction of IL‐33. The
Zhishan Xu   +11 more
wiley   +1 more source

Defining the Spatial Resolution of Analyte Recovery during Microperfusion-Based Sampling of Brain Parenchyma. [PDF]

open access: yesACS Chem Neurosci
Stangler LA   +9 more
europepmc   +1 more source

Hundred‐Nanometer‐Thick Stretchable Liquid Metal Films for Ultra‐Conformal Bioelectrodes

open access: yesAdvanced Science, EarlyView.
A low‐temperature deposition strategy is proposed to fabricate 19 nm‐thick liquid metal nanofilms (conductivity: 3 × 10⁶ S m−1) for developing ultra‐thin, high‐conductivity epidermal electrodes. The 1 µm‐thick composite achieves 8.5 kΩ skin contact impedance and 26 dB EMG SNR, enabling robust dynamic electromyography during movement.
Shiying Li   +10 more
wiley   +1 more source

Activation of USP30 Disrupts Endothelial Cell Function and Aggravates Acute Lung Injury Through Regulating the S‐Adenosylmethionine Cycle

open access: yesAdvanced Science, EarlyView.
USP30 deubiquitinates and stabilizes MAT2A, thereby regulating DNA methylation and miRNA expression, which ultimately leads to disruption of lung endothelial barrier and inflammation. Abstract Microvascular dysfunction is a key contributor to the development of acute inflammatory diseases, characterized by heightened vascular hyperpermeability and ...
Baoyinna Baoyinna   +11 more
wiley   +1 more source

Controlled and orthogonal partitioning of large particles into biomolecular condensates. [PDF]

open access: yesNat Commun
Kelley FM   +10 more
europepmc   +1 more source

Dynamic Regulation of Granular Hydrogels Through Guest‐Host Interactions to Spatiotemporally Guide Cellular Migration

open access: yesAdvanced Science, EarlyView.
A dynamic granular system composed of microgels crosslinked through guest‐host interactions is developed to reversibly alter its stiffness and microporosity in response to chemical stimuli, enabling temporal regulation of cell migration. Suspension bioprinting using this dynamic hydrogel allows for 4D spatiotemporal control over tissue formation ...
Keisuke Nakamura   +4 more
wiley   +1 more source

BRIGHT Enables High‐SNR Live‐Cell Imaging of Non‐Repetitive Sequences via Bivalent Fluorescent Nanobody‐Mediated Cascade‐Dependent Illumination

open access: yesAdvanced Science, EarlyView.
BRIGHT is a newly developed live‐cell imaging system that integrates cascade amplification with background denoising through the bivalent binding capability and antigen‐dependent stability of a bivalent fluorescent nanobody targeting ALFA peptides.
Lei Feng   +9 more
wiley   +1 more source

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