Results 261 to 270 of about 100,399 (378)

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source

Laboratory Application of the Dextran-Coated-Charcoal Radioimmunoassay of Insulin [PDF]

, 1969
Nadine Poznanski, W.J. Poznanski
openalex   +1 more source

3D bioprinting of a perfusable skin-on-chip model suitable for drug testing and wound healing studies. [PDF]

Mater Today Bio
Maggiotto F, Dalla Valle E, Fietta A, Visentin LM, Giomo M, Cimetta E.   +5 more
europepmc   +1 more source

Harnessing the Immunomodulation of UV‐Exposed Keratinocyte Extracellular Vesicles for Inflammatory Disorder Treatment

Advanced Science, EarlyView.
Adopting a paradigm shift that transforms a known health hazard as a potential therapeutic asset, a novel therapeutic strategy is set out to investigate for inflammatory conditions by leveraging immunosuppressive properties of UV‐irradiated keratinocytes.
Lu Liu, Ding Yang, Jingsen Ji, Gengyou Li, Haoting Chen, Yuying Yao, Chenxing Fu, Fangling Liao, Jinzhao Liu, Yaming Zhang, Zechuan Li, Jing Zhang, Huike Ma, Jingxia Zhao, Ying‐Shi Sun, Weisheng Guo, Weiping Wang   +16 more
wiley   +1 more source

Ubiquitination‐Dependent LLGL2 Degradation Drives Colorectal Cancer Progression via THBS3 mRNA Stabilization

Advanced Science, EarlyView.
During the progression of CRC, MDM2, as an E3 ubiquitin ligase, promotes the degradation of the LLGL2 protein. Reduced expression of the LLGL2 protein leads to the loss of support for the CNOT1 protein, decreasing the degradation of THBS3 mRNA. The increased THBS3 further activates the PI3K‐Akt pathway, promoting the proliferation and metastasis of CRC.
Jiayan Huang, Tiantian Zhang, Huimin Li, Zidan Li, Shuangshuang Yin, Yiman Liu, Chunze Zhang, Yuling Qiu, Haiyang Yu   +8 more
wiley   +1 more source

Dextran sulfate precipitation and ultracentrifugation of lipoproteins from hypercholesterolemic dog serum

, 1962
T Sakagami, D.B. Zilversmit
openalex   +1 more source

Polyethersulfone mixed matrix membranes modified with pore formers and Ag-titanate nanotubes: physicochemical characteristics and (bio)fouling study. [PDF]

Environ Sci Pollut Res Int
Sałacińska A, Sienkiewicz P, Szymański K, Mozia S.   +3 more
europepmc   +1 more source

ε‐Poly‐L‐lysine‐graft‐oligo(3‐hexylthiophene) Copolymers as Antibacterial and Biodegradable Polymer Electronics

Advanced Science, EarlyView.
ε‐Poly‐L‐lysine‐graft‐oligo(3‐hexylthiophene) (EPL‐g‐O3HT) copolymers are engineered as biodegradable and antibacterial materials for transient electronics. EPL‐g‐O3HT exhibits tunable conductivity, controlled enzymatic degradability, good biocompatibility, and potent antibacterial activity. They are demonstrated in electromyography sensors and organic
Xin Sun, Eddie Wai Chi Chan, Fathumma Rizana Shiraz, Bicheng Zhu, Jingwen Yang, Katharina Matura, Viji Sarojini, Serpil Tekoglu, David Barker, Jadranka Travas‐Sejdic   +9 more
wiley   +1 more source

Targeting Tumor-Associated Macrophages with the Immune-Activating Nanomedicine for Achieving Strong Antitumor Activity with Rapid Clearance from the Body. [PDF]

ACS Nano
Ota Y, Inagaki R, Takanashi Y, Uemachi H, Matsuda K, Matsuoka M, Taoda R, Ohe S, Ishitsubo Y, Nakamura M, Goto M, Ban H, Nagai Y.   +12 more
europepmc   +1 more source

Anti‐Inflammatory Mechanisms of Selenium Nanosheets in Ulcerative Colitis: Protein Corona, GP130 Interaction, and Transcriptomic Profile

Advanced Science, EarlyView.
SeNSs provide a biocompatible, anti‐inflammatory UC therapy. SeNSs form protein coronas enriched with AKT/PI3K/NF‐κB pathway proteins, suppress GP130 via hydrophobic interactions, and inhibit pro‐inflammatory cytokines. In DSS‐induced UC mice, SeNSs reduce inflammation, tissue damage, and disease activity by modulating cytokine, chemokine, and ...
Dingyi Shen, Li Gong, Wei Yang, Jiaqi Luo, Zhen Jin, Youzhi Tang   +5 more
wiley   +1 more source