Results 281 to 290 of about 102,443 (368)

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Application of Gas-Phase Electrophoresis (nES GEMMA Instrumentation) in Molecular Weight Determination. [PDF]

J Mass Spectrom
Weiss VU, Szymanski WW, Marchetti-Deschmann M.   +2 more
europepmc   +1 more source

Membrane‐Penetrating Molecular Device Based on a Triplex Containing Acyclic L‐Threoninol Nucleic Acid Functionalized with Cholesterol

Angewandte Chemie, EarlyView.
A membrane‐penetrating molecular device composed of triplex containing cholesterol‐modified acyclic L‐threoninol nucleic acid (L‐aTNA) was achieved. This device is applied to a photo‐triggered signal transduction system functioning on giant unilamellar vesicles. Abstract Membrane‐penetrating molecular devices are valuable biological tools.
Kaifu Liu, Hiroyuki Asanuma, Keiji Murayama   +2 more
wiley   +1 more source

Controlled and orthogonal partitioning of large particles into biomolecular condensates. [PDF]

Nat Commun
Kelley FM, Ani A, Pinlac EG, Linders B, Favetta B, Barai M, Ma Y, Singh A, Dignon GL, Gu Y, Schuster BS.   +10 more
europepmc   +1 more source

Growth, Dissolution and Segregation of Genetically Encoded RNA Droplets by Ribozyme Catalysis

Angewandte Chemie, EarlyView.
Ribozymes enable sequence‐encoded turnover of RNA droplet material, resulting in transiently active droplets that selectively segregate based on their genotype. This establishes a direct link between genetic information and droplet behavior, marking a step toward programmable, evolvable RNA‐based compartments with life‐like properties.
Franziska Giessler, William Verstraeten, Tobias Abele, Stefan J. Maurer, Luca Monari, Kerstin Göpfrich   +5 more
wiley   +1 more source

Biotechnological potential and genomic analysis of the Leuconostoc mesenteroides F17 and F18 strains isolated from camel milk. [PDF]

BMC Microbiol
Zeid AF, Zarour K, Mohedano ML, Díez-Ozaeta I, López P.   +4 more
europepmc   +1 more source

Surface Avidity of Anionic Polypeptide Coatings on Layer‐by‐Layer Nanoparticles Target Cancer‐Associated Amino Acid Transporters

Angewandte Chemie, EarlyView.
Electrostatically layered nanoparticles (NPs) coated with anionic polypeptides selectively target cancer cells by engaging amino acid transporters. Poly(L‐glutamate) (PLE) coatings cluster the glutamine transporter SLC1A5, prolonging NP surface retention, while poly(L‐aspartate) (PLD) coatings also bind SLC1A3, potentially promoting faster ...
Ivan S. Pires, Margaret M. Billingsley, Ezra Gordon, Andrew J. Pickering, Eva Cai, Gonzalo J. Esparza, Mae L. Pryor, Alexander D. Stoneman, Aidan Kindopp, Darrell J. Irvine, Paula T. Hammond   +10 more
wiley   +1 more source

Advancing the Development of Subcutaneous Glucose Biosensors: Cargo-Carrying Adhesive Biosensor Systems (CABs). [PDF]

Macromol Biosci
Martinez CI, Ferrell TS, Krishnan VM, Grunlan MA.   +3 more
europepmc   +1 more source

Nanoparticle‐Based Tolerogenic Vaccines: Next‐Generation Strategies for Autoimmune and Allergic Disease Therapies

Angewandte Chemie, EarlyView.
Nanoparticle‐based tolerogenic vaccines harness controlled antigen delivery and immunomodulation to establish tolerance in autoimmunity and allergy. This review outlines how nanoparticle design (size, shape, composition, administration route) influences biodistribution and immune‐cell targeting.
Benjamin E. Nachod, Ajay S. Thatte, Rohan Palanki, Michael J. Mitchell   +3 more
wiley   +1 more source

Synthesis of Carboxymethyl Dextran-Coated Gold Nanoparticles as Stable and Storable Optical Labels for Ultrasensitive Plasmonic Nanoparticle-Linked Sorbent Assay. [PDF]

Sensors (Basel)
Sitinjak NA, Huang CW, Yang TY, Chau LK, Wang CH.   +4 more
europepmc   +1 more source